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TCF/LEF [nucleoplasm]
Stable Identifier
R-BTA-3299546
Type
Set [CandidateSet]
Species
Bos taurus
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Signal Transduction (Bos taurus)
Signaling by WNT (Bos taurus)
Degradation of beta-catenin by the destruction complex (Bos taurus)
Repression of WNT target genes (Bos taurus)
TLE tetramers bind TCF/LEF at WNT promoters (Bos taurus)
'canonical' WNT target gene:TCF/LEF:TLE tetramer [nucleoplasm] (Bos taurus)
'canonical' WNT target genes:TCF/LEF [nucleoplasm] (Bos taurus)
TCF/LEF [nucleoplasm] (Bos taurus)
'canonical' WNT target genes:TCF/LEF [nucleoplasm] (Bos taurus)
TCF/LEF [nucleoplasm] (Bos taurus)
TCF dependent signaling in response to WNT (Bos taurus)
Deactivation of the beta-catenin transactivating complex (Bos taurus)
TCF:Beta-catenin binds SOX proteins (Bos taurus)
TCF/LEF:CTNNB1 [nucleoplasm] (Bos taurus)
TCF/LEF [nucleoplasm] (Bos taurus)
TCF/LEF:CTNNB1:SOX4,SOX13,SOX17 [nucleoplasm] (Bos taurus)
TCF/LEF:CTNNB1 [nucleoplasm] (Bos taurus)
TCF/LEF [nucleoplasm] (Bos taurus)
beta-catenin is replaced by repression complexes at the promoter (Bos taurus)
TCF/LEF:CTNNB1:APC:CTBP:BTRC [nucleoplasm] (Bos taurus)
TCF/LEF [nucleoplasm] (Bos taurus)
TCF/LEF:TLE:HDAC1 [nucleoplasm] (Bos taurus)
TCF/LEF [nucleoplasm] (Bos taurus)
Formation of the beta-catenin:TCF transactivating complex (Bos taurus)
Beta-catenin displaces TLE:HDAC1 from TCF/LEF (Bos taurus)
TCF/LEF:CTNNB1 [nucleoplasm] (Bos taurus)
TCF/LEF [nucleoplasm] (Bos taurus)
TCF/LEF:TLE:HDAC1 [nucleoplasm] (Bos taurus)
TCF/LEF [nucleoplasm] (Bos taurus)
Beta-catenin recruits CBP/p300 (Bos taurus)
TCF/LEF:CTNNB1 [nucleoplasm] (Bos taurus)
TCF/LEF [nucleoplasm] (Bos taurus)
TCF/LEF:CTNNB1:CBP/p300 [nucleoplasm] (Bos taurus)
TCF/LEF:CTNNB1 [nucleoplasm] (Bos taurus)
TCF/LEF [nucleoplasm] (Bos taurus)
Beta-catenin recruits CDC73 and LEO1 (Bos taurus)
TCF/LEF:CTNNB1 [nucleoplasm] (Bos taurus)
TCF/LEF [nucleoplasm] (Bos taurus)
TCF/LEF:CTNNB1:PAF1-like complex [nucleoplasm] (Bos taurus)
TCF/LEF:CTNNB1 [nucleoplasm] (Bos taurus)
TCF/LEF [nucleoplasm] (Bos taurus)
Beta-catenin recruits SMARCA4 (Bos taurus)
TCF/LEF:CTNNB1 [nucleoplasm] (Bos taurus)
TCF/LEF [nucleoplasm] (Bos taurus)
TCF/LEF:CTNNB1:SMARCA4:TERT [nucleoplasm] (Bos taurus)
TCF/LEF:CTNNB1 [nucleoplasm] (Bos taurus)
TCF/LEF [nucleoplasm] (Bos taurus)
Beta-catenin recruits TRRAP/KAT5 HAT components (Bos taurus)
TCF/LEF:CTNNB1 [nucleoplasm] (Bos taurus)
TCF/LEF [nucleoplasm] (Bos taurus)
TCF/LEF:CTNNB1:RUVBL1:TRRAP:KAT5 [nucleoplasm] (Bos taurus)
TCF/LEF:CTNNB1 [nucleoplasm] (Bos taurus)
TCF/LEF [nucleoplasm] (Bos taurus)
Beta-catenin:TCF associates with BCL9 and PYGO (Bos taurus)
TCF/LEF:CTNNB1 [nucleoplasm] (Bos taurus)
TCF/LEF [nucleoplasm] (Bos taurus)
TCF/LEF:CTNNB1:BCL9:PYGO [nucleoplasm] (Bos taurus)
TCF/LEF [nucleoplasm] (Bos taurus)
Recruitment of SET1 methyltransferase complex (Bos taurus)
TCF/LEF:CTNNB1:BCL9:PYGO [nucleoplasm] (Bos taurus)
TCF/LEF [nucleoplasm] (Bos taurus)
TCF/LEF:CTNNB1:BCL9:PYGO:SET1-like complex [nucleoplasm] (Bos taurus)
TCF/LEF [nucleoplasm] (Bos taurus)
SET1 complex trimethylates H3K4 at the MYC gene (Bos taurus)
TCF/LEF:CTNNB1:BCL9:PYGO:SET1-like complex [nucleoplasm] (Bos taurus)
TCF/LEF [nucleoplasm] (Bos taurus)
Participants
members
TCF7L2 [nucleoplasm]
(Bos taurus)
LEF1 [nucleoplasm]
(Bos taurus)
candidates
TCF7 [nucleoplasm]
(Bos taurus)
TCF7L1 [nucleoplasm]
(Bos taurus)
Participates
as a component of
'canonical' WNT target genes:TCF/LEF [nucleoplasm] (Bos taurus)
TCF/LEF:CTNNB1:BCL9:PYGO [nucleoplasm] (Bos taurus)
TCF/LEF:CTNNB1:BCL9:PYGO:SET1-like complex [nucleoplasm] (Bos taurus)
TCF/LEF:CTNNB1:APC:CTBP:BTRC [nucleoplasm] (Bos taurus)
TCF/LEF:TLE:HDAC1 [nucleoplasm] (Bos taurus)
TCF/LEF:CTNNB1 [nucleoplasm] (Bos taurus)
Inferred From
TCF/LEF [nucleoplasm]
(Homo sapiens)
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