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SIN3A [nucleoplasm]
Stable Identifier
R-BTA-351657
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
nucleoplasm
Synonyms
SIN3A, F1MTR3
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Bos taurus)
Cellular responses to stress (Bos taurus)
Cellular response to chemical stress (Bos taurus)
Cytoprotection by HMOX1 (Bos taurus)
Fatty acid ligands activate PPARA (Bos taurus)
Corepressors of PPARalpha [nucleoplasm] (Bos taurus)
SIN3A [nucleoplasm] (Bos taurus)
PPARA:RXRA:Corepressors [nucleoplasm] (Bos taurus)
Corepressors of PPARalpha [nucleoplasm] (Bos taurus)
SIN3A [nucleoplasm] (Bos taurus)
Developmental Biology (Bos taurus)
MITF-M-regulated melanocyte development (Bos taurus)
MITF-M-dependent gene expression (Bos taurus)
Regulation of MITF-M-dependent genes involved in apoptosis (Bos taurus)
HINT1, SIN3A and HDAC1 bind MITF-M at the BCL2 promoter (Bos taurus)
HDAC1:SIN3A:HINT1:MITF-M:BCL2 gene [nucleoplasm] (Bos taurus)
SIN3A [nucleoplasm] (Bos taurus)
SIN3A [nucleoplasm] (Bos taurus)
Regulation of MITF-M-dependent genes involved in cell cycle and proliferation (Bos taurus)
HINT1, HDAC1, and SIN3A bind CTNNB1 at the CCND1 promoter (Bos taurus)
HINT1:HDAC1:SIN3A:TCF/LEF:CTNNB1:CCND1 gene [nucleoplasm] (Bos taurus)
SIN3A [nucleoplasm] (Bos taurus)
SIN3A [nucleoplasm] (Bos taurus)
Gene expression (Transcription) (Bos taurus)
RNA Polymerase II Transcription (Bos taurus)
Generic Transcription Pathway (Bos taurus)
Transcriptional Regulation by MECP2 (Bos taurus)
Regulation of MECP2 expression and activity (Bos taurus)
MECP2 binds the SIN3A co-repressor complex (Bos taurus)
MECP2:SIN3A:HDAC1,HDAC2 [nucleoplasm] (Bos taurus)
MECP2:SIN3A:HDAC1 [nucleoplasm] (Bos taurus)
SIN3A:HDAC1 homodimer [nucleoplasm] (Bos taurus)
SIN3A [nucleoplasm] (Bos taurus)
MECP2:SIN3A:HDAC1:HDAC2 [nucleoplasm] (Bos taurus)
SIN3A:HDAC1:HDAC2 [nucleoplasm] (Bos taurus)
SIN3A [nucleoplasm] (Bos taurus)
MECP2:SIN3A:HDAC2 [nucleoplasm] (Bos taurus)
SIN3A:HDAC2 homodimer [nucleoplasm] (Bos taurus)
SIN3A [nucleoplasm] (Bos taurus)
SIN3A:HDAC1,HDAC2 dimers [nucleoplasm] (Bos taurus)
SIN3A:HDAC1 homodimer [nucleoplasm] (Bos taurus)
SIN3A [nucleoplasm] (Bos taurus)
SIN3A:HDAC1:HDAC2 [nucleoplasm] (Bos taurus)
SIN3A [nucleoplasm] (Bos taurus)
SIN3A:HDAC2 homodimer [nucleoplasm] (Bos taurus)
SIN3A [nucleoplasm] (Bos taurus)
Transcriptional regulation by RUNX1 (Bos taurus)
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function (Bos taurus)
PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter (Bos taurus)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:GP1BA gene:H3K4me2,H3R2me2a-Nucleosome [nucleoplasm] (Bos taurus)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Bos taurus)
SIN3A,(SIN3B) [nucleoplasm] (Bos taurus)
SIN3A [nucleoplasm] (Bos taurus)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:GP1BA gene:H3K4me2-Nucleosome [nucleoplasm] (Bos taurus)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Bos taurus)
SIN3A,(SIN3B) [nucleoplasm] (Bos taurus)
SIN3A [nucleoplasm] (Bos taurus)
PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter (Bos taurus)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:ITGA2B gene:H3K4me2,H3R2me2a-Nucleosome [nucleoplasm] (Bos taurus)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Bos taurus)
SIN3A,(SIN3B) [nucleoplasm] (Bos taurus)
SIN3A [nucleoplasm] (Bos taurus)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:ITGA2B gene:H3K4me2-Nucleosome [nucleoplasm] (Bos taurus)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Bos taurus)
SIN3A,(SIN3B) [nucleoplasm] (Bos taurus)
SIN3A [nucleoplasm] (Bos taurus)
PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter (Bos taurus)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:MIR27A gene:H3K4me2,H3R2me2a-Nucleosome [nucleoplasm] (Bos taurus)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Bos taurus)
SIN3A,(SIN3B) [nucleoplasm] (Bos taurus)
SIN3A [nucleoplasm] (Bos taurus)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:MIR27A gene:H3K4me2-Nucleosome [nucleoplasm] (Bos taurus)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Bos taurus)
SIN3A,(SIN3B) [nucleoplasm] (Bos taurus)
SIN3A [nucleoplasm] (Bos taurus)
PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter (Bos taurus)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:THBS1 gene:H3K4me2-Nucleosome [nucleoplasm] (Bos taurus)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Bos taurus)
SIN3A,(SIN3B) [nucleoplasm] (Bos taurus)
SIN3A [nucleoplasm] (Bos taurus)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:THBS1B gene:H3K4me2,H3R2me2a-Nucleosome [nucleoplasm] (Bos taurus)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Bos taurus)
SIN3A,(SIN3B) [nucleoplasm] (Bos taurus)
SIN3A [nucleoplasm] (Bos taurus)
RUNX1 binds SIN3A,(SIN3B) co-repressor (Bos taurus)
RUNX1:CBFB:SIN3A(SIN3B):PRMT6:HDAC1 [nucleoplasm] (Bos taurus)
SIN3A,(SIN3B) [nucleoplasm] (Bos taurus)
SIN3A [nucleoplasm] (Bos taurus)
SIN3A,(SIN3B) [nucleoplasm] (Bos taurus)
SIN3A [nucleoplasm] (Bos taurus)
Metabolism (Bos taurus)
Metabolism of lipids (Bos taurus)
Regulation of lipid metabolism by PPARalpha (Bos taurus)
Fatty acid ligands activate PPARA (Bos taurus)
Corepressors of PPARalpha [nucleoplasm] (Bos taurus)
SIN3A [nucleoplasm] (Bos taurus)
PPARA:RXRA:Corepressors [nucleoplasm] (Bos taurus)
Corepressors of PPARalpha [nucleoplasm] (Bos taurus)
SIN3A [nucleoplasm] (Bos taurus)
PPARA binds fibrates (Bos taurus)
Corepressors of PPARalpha [nucleoplasm] (Bos taurus)
SIN3A [nucleoplasm] (Bos taurus)
PPARA:RXRA:Corepressors [nucleoplasm] (Bos taurus)
Corepressors of PPARalpha [nucleoplasm] (Bos taurus)
SIN3A [nucleoplasm] (Bos taurus)
PPARA:RXRA binds Corepressors of PPARA (Bos taurus)
Corepressors of PPARalpha [nucleoplasm] (Bos taurus)
SIN3A [nucleoplasm] (Bos taurus)
PPARA:RXRA:Corepressors [nucleoplasm] (Bos taurus)
Corepressors of PPARalpha [nucleoplasm] (Bos taurus)
SIN3A [nucleoplasm] (Bos taurus)
Metabolism of proteins (Bos taurus)
Post-translational protein modification (Bos taurus)
SUMOylation (Bos taurus)
SUMO E3 ligases SUMOylate target proteins (Bos taurus)
SUMOylation of transcription cofactors (Bos taurus)
TOPORS SUMOylates SIN3A with SUMO1 (Bos taurus)
SIN3A [nucleoplasm] (Bos taurus)
External Reference Information
External Reference
UniProt:F1MTR3
Gene Names
SIN3A
Reference Genes
BioGPS Gene:518504 SIN3A
ENSEMBL:ENSBTAG00000009985.6
ENSEMBL:ENSBTAG00000009985.7 SIN3A
KEGG Gene (Bos taurus):518504 SIN3A
Monarch:518504 SIN3A
NCBI Gene:518504 SIN3A
Reference Transcript
RefSeq:XM_015468524.1 SIN3A
RefSeq:XM_875451.6 SIN3A
RefSeq:XM_015459266.1 SIN3A
RefSeq:XM_002696631.3 SIN3A
Other Identifiers
GO:0000118
GO:0000122
GO:0000228
GO:0000278
GO:0000776
GO:0000785
GO:0001701
GO:0002218
GO:0002230
GO:0002244
GO:0002376
GO:0003677
GO:0003682
GO:0003714
GO:0005634
GO:0005654
GO:0005667
GO:0005694
GO:0006260
GO:0006325
GO:0006351
GO:0006355
GO:0008104
GO:0010971
GO:0012501
GO:0017053
GO:0021895
GO:0023052
GO:0030154
GO:0030516
GO:0031507
GO:0042754
GO:0043066
GO:0043226
GO:0045666
GO:0045892
GO:0048856
GO:0051595
GO:0060337
GO:0061629
GO:0070822
GO:0071333
GO:0098542
GO:0098772
GO:0140110
GO:0140416
GO:1900181
Participates
as an input of
TOPORS SUMOylates SIN3A with SUMO1 (Bos taurus)
HINT1, SIN3A and HDAC1 bind MITF-M at the BCL2 promoter (Bos taurus)
HINT1, HDAC1, and SIN3A bind CTNNB1 at the CCND1 promoter (Bos taurus)
as a component of
HDAC1:SIN3A:HINT1:MITF-M:BCL2 gene [nucleoplasm] (Bos taurus)
HINT1:HDAC1:SIN3A:TCF/LEF:CTNNB1:CCND1 gene [nucleoplasm] (Bos taurus)
SIN3A:HDAC2 homodimer [nucleoplasm] (Bos taurus)
SIN3A:HDAC1 homodimer [nucleoplasm] (Bos taurus)
SIN3A:HDAC1:HDAC2 [nucleoplasm] (Bos taurus)
as a member of
SIN3A,(SIN3B) [nucleoplasm] (Bos taurus)
Corepressors of PPARalpha [nucleoplasm] (Bos taurus)
Other forms of this molecule
SIN3A [nucleoplasm]
Inferred From
SIN3A [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
XP_002696677.1
,
XP_015314752.1
,
XP_015324010.1
,
XP_880544.4
OpenTargets
ENSG00000169375
Ensembl
ENSBTAT00000013167
,
ENSBTAG00000009985
,
ENSBTAP00000013167
VGNC
34624
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