Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
PTK2B [cytosol]
Stable Identifier
R-BTA-390932
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
cytosol
Synonyms
PTK2B, A0A3Q1LVP1
Locations in the PathwayBrowser
Expand all
Cell-Cell communication (Bos taurus)
Signal regulatory protein family interactions (Bos taurus)
p-4Y-SIRPA:CD47 binds PTK2B (Bos taurus)
PTK2B [cytosol] (Bos taurus)
p-Y428,Y452,Y469,Y495-SIRPA:CD47:PTK2B [plasma membrane] (Bos taurus)
PTK2B [cytosol] (Bos taurus)
Immune System (Bos taurus)
Cytokine Signaling in Immune system (Bos taurus)
Signaling by Interleukins (Bos taurus)
Interleukin-2 family signaling (Bos taurus)
Interleukin-2 signaling (Bos taurus)
PTK2B binds JAK3 (Bos taurus)
JAK3:PYK2 [cytosol] (Bos taurus)
PTK2B [cytosol] (Bos taurus)
PTK2B [cytosol] (Bos taurus)
PTK2B is phosphorylated (Bos taurus)
JAK3:PYK2 [cytosol] (Bos taurus)
PTK2B [cytosol] (Bos taurus)
Signal Transduction (Bos taurus)
Signaling by Receptor Tyrosine Kinases (Bos taurus)
Signaling by VEGF (Bos taurus)
VEGFA-VEGFR2 Pathway (Bos taurus)
PTK2beta binds alphaVbeta3 (Bos taurus)
PTK2B [cytosol] (Bos taurus)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3:PTK2B [plasma membrane] (Bos taurus)
PTK2B [cytosol] (Bos taurus)
SRC-1 phosphorylates PTK2-beta (Bos taurus)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3:PTK2B [plasma membrane] (Bos taurus)
PTK2B [cytosol] (Bos taurus)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Bos taurus)
Signaling by Rho GTPases (Bos taurus)
RHO GTPase cycle (Bos taurus)
RHOU GTPase cycle (Bos taurus)
RHOU binds effectors at the plasma membrane (Bos taurus)
RHOU effectors [cytosol] (Bos taurus)
PTK2B [cytosol] (Bos taurus)
RHOU:GTP:RHOU effectors [plasma membrane] (Bos taurus)
RHOU effectors [cytosol] (Bos taurus)
PTK2B [cytosol] (Bos taurus)
External Reference Information
External Reference
UniProt:A0A3Q1LVP1
Gene Names
PTK2B
Reference Genes
BioGPS Gene:541008 PTK2B
ENSEMBL:ENSBTAG00000005958.6
Monarch:541008 PTK2B
NCBI Gene:541008 PTK2B
UCSC:A0A3Q1LVP1 PTK2B
Reference Transcript
RefSeq:XM_059889217.1 PTK2B
RefSeq:XM_059889218.1 PTK2B
Other Identifiers
541008
Bt.13853.1.S1_at
Bt.13853.2.S1_a_at
GO:0001764
GO:0001954
GO:0002040
GO:0002315
GO:0003824
GO:0004672
GO:0004713
GO:0004715
GO:0005524
GO:0005634
GO:0005856
GO:0005925
GO:0006468
GO:0007010
GO:0007030
GO:0007166
GO:0007172
GO:0007229
GO:0008284
GO:0008285
GO:0008360
GO:0010595
GO:0010758
GO:0010976
GO:0016740
GO:0030027
GO:0030155
GO:0030335
GO:0030502
GO:0030838
GO:0030865
GO:0032956
GO:0033209
GO:0043066
GO:0043267
GO:0045453
GO:0045638
GO:0045766
GO:0046330
GO:0048010
GO:0048471
GO:0048870
GO:0051279
GO:0051897
GO:0065003
GO:0070098
GO:0070374
GO:0071300
GO:0071498
GO:0086100
GO:0098793
GO:0098978
GO:0099092
GO:0099151
GO:0140096
GO:2000058
GO:2000060
GO:2000538
Participates
as a member of
RHOU effectors [cytosol] (Bos taurus)
as an input of
p-4Y-SIRPA:CD47 binds PTK2B (Bos taurus)
PTK2B binds JAK3 (Bos taurus)
PTK2beta binds alphaVbeta3 (Bos taurus)
as a component of
p-Y428,Y452,Y469,Y495-SIRPA:CD47:PTK2B [plasma membrane] (Bos taurus)
JAK3:PYK2 [cytosol] (Bos taurus)
VEGFA:p-6Y-VEGFR2:Integrin alphaVbeta3:PTK2B [plasma membrane] (Bos taurus)
Other forms of this molecule
phospho-PTK2B [cytosol]
phospho-PTK2B [cytosol]
Inferred From
PTK2B [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_059745200.1
,
XP_059745201.1
ENSEMBL
ENSBTAT00000084967
,
ENSBTAG00000005958
,
ENSBTAP00000059391
VGNC
33519
© 2026
Reactome
This website requires cookies and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our
Privacy Notice
.
I agree, dismiss this banner
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text