Reactome | polySUMO2,3-K263-NPM1 [nucleoplasm]

polySUMO2,3-K263-NPM1 [nucleoplasm]

Stable Identifier

R-BTA-4086056

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

nucleoplasm

Synonyms

A0A3Q1LR94

Locations in the PathwayBrowser

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Metabolism of proteins (Bos taurus)

- Post-translational protein modification (Bos taurus)
  - SUMOylation (Bos taurus)
    - SUMO E3 ligases SUMOylate target proteins (Bos taurus)
      - SUMOylation of transcription cofactors (Bos taurus)
        
        SUMOylation of NPM1 with SUMO2,3 (Bos taurus)
        
        Homologues of polySUMO2,3-K263-NPM1 [nucleoplasm] (Bos taurus)
        
        polySUMO2,3-K263-NPM1 [nucleoplasm] (Bos taurus)

External Reference Information

External Reference

UniProt:A0A3Q1LR94

Reference Genes

ENSEMBL:ENSBTAG00000003838.6

UCSC:A0A3Q1LR94

Participates

as a member of

Homologues of polySUMO2,3-K263-NPM1 [nucleoplasm] (Bos taurus)

Other forms of this molecule

monoSUMO1-K263-NPM1 [nucleoplasm]

NPM1 [nucleoplasm]

phospho-p-S4-NPM1 [cytosol]

NPM1 [cytosol]

Inferred From

polySUMO2,3-K263-NPM1 [nucleoplasm] (Homo sapiens)

Modified Residues

Name

sumoylated lysine (polySUMO2,3 [nucleoplasm]) at 263 (in Homo sapiens)

Coordinate

263

Modification

polySUMO2,3 [nucleoplasm]

PsiMod Name

sumoylated lysine

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.

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