Reactome | PSPN [extracellular region]

PSPN [extracellular region]

Stable Identifier

R-BTA-434907

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

extracellular region

Synonyms

PSPN, E1BCL0

Locations in the PathwayBrowser

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Developmental Biology (Bos taurus)

- Nervous system development (Bos taurus)
  - Axon guidance (Bos taurus)
    - RET signaling (Bos taurus)
      - 2x p-5Y-RET:GDNF:GFRA complexes bind FRS2 (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Bos taurus)
        
        PSPN [extracellular region] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:FRS2 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Bos taurus)
        
        PSPN [extracellular region] (Bos taurus)
      - 2x p-5Y-RET:GDNF:GFRA complexes bind GRB2-1:SOS1 (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Bos taurus)
        
        PSPN [extracellular region] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:GRB2-1:SOS1 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Bos taurus)
        
        PSPN [extracellular region] (Bos taurus)
      - 2x p-5Y-RET:GDNF:GFRA complexes bind GRB7,10 (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Bos taurus)
        
        PSPN [extracellular region] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:GRB7,GRB10 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Bos taurus)
        
        PSPN [extracellular region] (Bos taurus)
      - 2x p-5Y-RET:GDNF:GFRA complexes bind PLCgamma1 (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Bos taurus)
        
        PSPN [extracellular region] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:PLCG1 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Bos taurus)
        
        PSPN [extracellular region] (Bos taurus)
      - 2x p-5Y-RET:GDNF:GFRA complexes bind RET interactors (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Bos taurus)
        
        PSPN [extracellular region] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:RET interactors [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Bos taurus)
        
        PSPN [extracellular region] (Bos taurus)
      - 2x p-5Y-RET:GDNF:GFRA complexes bind SHC1 (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Bos taurus)
        
        PSPN [extracellular region] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:SHC1 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Bos taurus)
        
        PSPN [extracellular region] (Bos taurus)
      - 2x p-5Y-RET:GDNF:GFRA complexes bind SRC1, RAP1GAP (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Bos taurus)
        
        PSPN [extracellular region] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:SRC-1,RAP1GAP [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Bos taurus)
        
        PSPN [extracellular region] (Bos taurus)
      - 2x p-5Y-RET:GDNF:GFRA complexes binds DOK1,DOK2,DOK4,DOK5,DOK6 (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Bos taurus)
        
        PSPN [extracellular region] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:DOK1,DOK2,DOK4,DOK5,DOK6 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Bos taurus)
        
        PSPN [extracellular region] (Bos taurus)
      - 2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 binds GRB2-1:SOS1 (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Bos taurus)
        
        PSPN [extracellular region] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1:SOS1 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Bos taurus)
        
        PSPN [extracellular region] (Bos taurus)
      - GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:GAB1,GAB2 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:GRB2-1 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Bos taurus)
        
        PSPN [extracellular region] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Bos taurus)
        
        PSPN [extracellular region] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:GRB2-1 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Bos taurus)
        
        PSPN [extracellular region] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Bos taurus)
        
        PSPN [extracellular region] (Bos taurus)
      - PKA phosphorylates RET:GDNF:GFRA dimer (Bos taurus)
        
        2x RET:GFRA:GDNF complexes [plasma membrane] (Bos taurus)
        
        RET:GFRA:GDNF complexes [plasma membrane] (Bos taurus)
        
        RET:GFRA4:PSPN [plasma membrane] (Bos taurus)
        
        PSPN [extracellular region] (Bos taurus)
      - PSPN binds RET:GFRA4 (Bos taurus)
        
        PSPN [extracellular region] (Bos taurus)
        
        RET:GFRA4:PSPN [plasma membrane] (Bos taurus)
        
        PSPN [extracellular region] (Bos taurus)
      - RET dimerizes (Bos taurus)
        
        2x RET:GFRA:GDNF complexes [plasma membrane] (Bos taurus)
        
        RET:GFRA:GDNF complexes [plasma membrane] (Bos taurus)
        
        RET:GFRA4:PSPN [plasma membrane] (Bos taurus)
        
        PSPN [extracellular region] (Bos taurus)
        
        RET:GFRA:GDNF complexes [plasma membrane] (Bos taurus)
        
        RET:GFRA4:PSPN [plasma membrane] (Bos taurus)
        
        PSPN [extracellular region] (Bos taurus)
      - RET tyrosine phosphorylation (Bos taurus)
        
        2x RET:GFRA:GDNF complexes [plasma membrane] (Bos taurus)
        
        RET:GFRA:GDNF complexes [plasma membrane] (Bos taurus)
        
        RET:GFRA4:PSPN [plasma membrane] (Bos taurus)
        
        PSPN [extracellular region] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Bos taurus)
        
        PSPN [extracellular region] (Bos taurus)
      - SHC1 in the RET complex is phosphorylated (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:SHC1 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Bos taurus)
        
        PSPN [extracellular region] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Bos taurus)
        
        PSPN [extracellular region] (Bos taurus)
      - p-5Y-GAB in RET-GRB2-GAB complexes binds PTPN11 (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:GRB2-1 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Bos taurus)
        
        PSPN [extracellular region] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Bos taurus)
        
        PSPN [extracellular region] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2:PTPN11 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:GRB2-1 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Bos taurus)
        
        PSPN [extracellular region] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Bos taurus)
        
        PSPN [extracellular region] (Bos taurus)
      - p-5Y-GAB in the RET-GRB2-GAB complexes binds p85-PI3K (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:GRB2-1 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Bos taurus)
        
        PSPN [extracellular region] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Bos taurus)
        
        PSPN [extracellular region] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2:p85-containing Class 1A PI3Ks [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:p-5Y-GAB1,p-5Y-GAB2 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:GRB2-1 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Bos taurus)
        
        PSPN [extracellular region] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Bos taurus)
        
        PSPN [extracellular region] (Bos taurus)
      - p-5Y-RET complexes bind GRB2 (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:GRB2-1 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Bos taurus)
        
        PSPN [extracellular region] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Bos taurus)
        
        PSPN [extracellular region] (Bos taurus)
        
        p-5Y-RET:GDNF:GFRA complexes with and without p-SHC1 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Bos taurus)
        
        PSPN [extracellular region] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Bos taurus)
        
        PSPN [extracellular region] (Bos taurus)
      - p-5Y-RET-GRB2-containing complexes bind GAB1,GAB2 (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:GRB2-1 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Bos taurus)
        
        PSPN [extracellular region] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Bos taurus)
        
        PSPN [extracellular region] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1:GAB1,GAB2 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes with, without p-SHC1:GRB2-1 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:GRB2-1 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Bos taurus)
        
        PSPN [extracellular region] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Bos taurus)
        
        PSPN [extracellular region] (Bos taurus)

Signal Transduction (Bos taurus)

- MAPK family signaling cascades (Bos taurus)
  - MAPK1/MAPK3 signaling (Bos taurus)
    - RAF/MAP kinase cascade (Bos taurus)
      - RAS GEFs promote RAS nucleotide exchange (Bos taurus)
        
        RAS GEFs [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:GRB2-1:SOS1 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Bos taurus)
        
        PSPN [extracellular region] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1:GRB2-1:SOS1 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes:p-Y349,Y350,Y427-SHC1 [plasma membrane] (Bos taurus)
        
        2x p-5Y-RET:GDNF:GFRA complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA:GDNF complexes [plasma membrane] (Bos taurus)
        
        p-5Y-RET:GFRA4:PSPN [plasma membrane] (Bos taurus)
        
        PSPN [extracellular region] (Bos taurus)

External Reference Information

External Reference

UniProt:E1BCL0

Gene Names

PSPN

Reference Genes

ENSEMBL:ENSBTAG00000031794.3

Other Identifiers

518266

GO:0005576

GO:0005615

GO:0007165

GO:0008083

GO:0023052

GO:0030116

GO:0030971

GO:0048018

GO:0048731

GO:0048856

GO:0098772

Participates

as an input of

PSPN binds RET:GFRA4 (Bos taurus)

as a component of

Inferred From

PSPN [extracellular region] (Homo sapiens)

Cross References

OpenTargets

ENSG00000125650

Ensembl

ENSBTAT00000111762, ENSBTAP00000100126, ENSBTAG00000065591

VGNC

52869

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