Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
Me2sR4-HIST1H4 [nucleoplasm]
Stable Identifier
R-BTA-4754243
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
nucleoplasm
Synonyms
P62803
Locations in the PathwayBrowser
Expand all
Chromatin organization (Bos taurus)
Chromatin modifying enzymes (Bos taurus)
HDMs demethylate histones (Bos taurus)
JMJD6 demethylates Me2sR4-HIST1H4 (Bos taurus)
Me2sR4-HIST1H4 [nucleoplasm] (Bos taurus)
RMTs methylate histone arginines (Bos taurus)
COPRS:CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-4 of histone H4 (H4R3) (Bos taurus)
Me2sR4-HIST1H4, MeR4-HIST1H4 [nucleoplasm] (Bos taurus)
Me2sR4-HIST1H4 [nucleoplasm] (Bos taurus)
DNMT3A binds Me2sR4-HIST1H4 (Bos taurus)
Me2R4-HIST1H4:DNMT3A [nucleoplasm] (Bos taurus)
Me2sR4-HIST1H4 [nucleoplasm] (Bos taurus)
Me2sR4-HIST1H4 [nucleoplasm] (Bos taurus)
External Reference Information
External Reference
UniProt:P62803 Unknown
Chain
initiator methionine:, chain:2-103
Reference Genes
BioGPS Gene:280691
BioGPS Gene:526789
BioGPS Gene:527645
BioGPS Gene:530773
BioGPS Gene:617875
ENSEMBL:ENSBTAG00000030504.4
ENSEMBL:ENSBTAG00000032453.4
ENSEMBL:ENSBTAG00000060177.1
ENSEMBL:ENSBTAG00000060235.1
ENSEMBL:ENSBTAG00000067836.1
ENSEMBL:ENSBTAG00000068489.1
KEGG Gene (Bos taurus):526789
KEGG Gene (Bos taurus):527645
KEGG Gene (Bos taurus):530773
KEGG Gene (Bos taurus):617875
Monarch:280691
Monarch:526789
Monarch:527645
Monarch:530773
Monarch:617875
NCBI Gene:280691
NCBI Gene:526789
NCBI Gene:527645
NCBI Gene:530773
NCBI Gene:617875
Reference Transcript
RefSeq:XM_002697470.4
RefSeq:XM_002684630.3
RefSeq:XM_605163.4
RefSeq:XM_868981.6
RefSeq:NM_001099724.2
RefSeq:NM_001145871.2
RefSeq:NM_173880.2
Other Identifiers
115945168
115945170
115945172
280691
518961
527388
527645
528329
617905
GO:0000786
GO:0003677
GO:0005198
GO:0005634
GO:0005654
GO:0005694
GO:0006325
GO:0006334
GO:0030527
GO:0043226
GO:0046982
GO:0065003
Participates
as an input of
DNMT3A binds Me2sR4-HIST1H4 (Bos taurus)
JMJD6 demethylates Me2sR4-HIST1H4 (Bos taurus)
as a candidate of
Me2sR4-HIST1H4, MeR4-HIST1H4 [nucleoplasm] (Bos taurus)
as a component of
Me2R4-HIST1H4:DNMT3A [nucleoplasm] (Bos taurus)
Other forms of this molecule
polySUMO3-HIST1H4 [nucleoplasm]
monoSUMO1-HIST1H4 [nucleoplasm]
AcK5,12-HIST1H4A [nucleoplasm]
AcK13-HIST1H4 [nucleoplasm]
Me2aR4-HIST1H4 [nucleoplasm]
MeR4-HIST1H4 [nucleoplasm]
Me3K21-HIST1H4 [nucleoplasm]
AcK17-HIST1H4 [nucleoplasm]
AcK6-HIST1H4 [nucleoplasm]
AcK9-HIST1H4 [nucleoplasm]
AcK-HIST1H4 [nucleoplasm]
MeK21-HIST1H4 [nucleoplasm]
Me2K21-HIST1H4 [nucleoplasm]
Histone H4 [nucleoplasm]
Inferred From
Me2sR4-HIST1H4 [nucleoplasm]
(Homo sapiens)
Modified Residues
Name
symmetric dimethyl-L-arginine at 4 (in Homo sapiens)
Coordinate
4
PsiMod Name
symmetric dimethyl-L-arginine
PsiMod Definition
A protein modification that effectively converts an L-arginine residue to symmetric dimethylarginine, N(omega),N'(omega)-dimethyl-L-arginine.
Cross References
RefSeq
XP_874074.1
,
NP_001093194.1
,
NP_001139343.1
,
XP_605163.2
,
NP_776305.1
,
XP_002684676.1
,
XP_002697516.1
Ensembl
ENSBTAP00000052235
,
ENSBTAT00000054510
,
ENSBTAG00000067836
,
ENSBTAT00000056505
,
ENSBTAP00000053034
,
ENSBTAG00000068489
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text