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CTSZ [COPII-coated ER to Golgi transport vesicle]
Stable Identifier
R-BTA-5689727
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
COPII-coated ER to Golgi transport vesicle
Synonyms
(Glc)3(GlcNAc)2(Man)9-CTSZ, P05689
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Bos taurus)
Post-translational protein modification (Bos taurus)
Asparagine N-linked glycosylation (Bos taurus)
Transport to the Golgi and subsequent modification (Bos taurus)
ER to Golgi Anterograde Transport (Bos taurus)
COPII-mediated vesicle transport (Bos taurus)
BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Bos taurus)
COPII cargo:receptors:v:SNAREs:GOLGA2:GORASP1:USO1 homodimer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Bos taurus)
LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Bos taurus)
glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
CTSZ [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
COPII coat binds TRAPPCII and RAB1:GDP (Bos taurus)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Bos taurus)
COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Bos taurus)
LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Bos taurus)
glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
CTSZ [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Bos taurus)
COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Bos taurus)
LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Bos taurus)
glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
CTSZ [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
CSNK1D phosphorylates SEC23 (Bos taurus)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Bos taurus)
COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Bos taurus)
LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Bos taurus)
glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
CTSZ [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
COPII cargo:receptors:v:SNAREs:GOLGA2:GORASP1:USO1 homodimer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Bos taurus)
LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Bos taurus)
glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
CTSZ [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
Nucleotide exchange on RAB1 (Bos taurus)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Bos taurus)
COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Bos taurus)
LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Bos taurus)
glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
CTSZ [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Bos taurus)
COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Bos taurus)
LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Bos taurus)
glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
CTSZ [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Bos taurus)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Bos taurus)
COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Bos taurus)
LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Bos taurus)
glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
CTSZ [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Bos taurus)
COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Bos taurus)
LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Bos taurus)
glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
CTSZ [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
Vesicle budding (Bos taurus)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Bos taurus)
COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Bos taurus)
LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Bos taurus)
glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
CTSZ [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
Vesicle-mediated transport (Bos taurus)
Membrane Trafficking (Bos taurus)
ER to Golgi Anterograde Transport (Bos taurus)
COPII-mediated vesicle transport (Bos taurus)
BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Bos taurus)
COPII cargo:receptors:v:SNAREs:GOLGA2:GORASP1:USO1 homodimer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Bos taurus)
LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Bos taurus)
glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
CTSZ [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
COPII coat binds TRAPPCII and RAB1:GDP (Bos taurus)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Bos taurus)
COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Bos taurus)
LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Bos taurus)
glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
CTSZ [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Bos taurus)
COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Bos taurus)
LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Bos taurus)
glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
CTSZ [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
CSNK1D phosphorylates SEC23 (Bos taurus)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Bos taurus)
COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Bos taurus)
LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Bos taurus)
glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
CTSZ [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
COPII cargo:receptors:v:SNAREs:GOLGA2:GORASP1:USO1 homodimer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Bos taurus)
LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Bos taurus)
glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
CTSZ [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
Nucleotide exchange on RAB1 (Bos taurus)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Bos taurus)
COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Bos taurus)
LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Bos taurus)
glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
CTSZ [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Bos taurus)
COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Bos taurus)
LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Bos taurus)
glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
CTSZ [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Bos taurus)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Bos taurus)
COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Bos taurus)
LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Bos taurus)
glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
CTSZ [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Bos taurus)
COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Bos taurus)
LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Bos taurus)
glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
CTSZ [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
Vesicle budding (Bos taurus)
COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Bos taurus)
COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Bos taurus)
LMAN receptor:glycosylated cargo [ER to Golgi transport vesicle membrane] (Bos taurus)
glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
CTSZ [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
External Reference Information
External Reference
UniProt:P05689
Gene Names
CTSZ
Reference Genes
BioGPS Gene:404187 CTSZ
ENSEMBL:ENSBTAG00000018784
KEGG Gene (Bos taurus):404187 CTSZ
Monarch:404187 CTSZ
NCBI Gene:404187 CTSZ
Reference Transcript
RefSeq:NM_001077835.1 CTSZ
Other Identifiers
404187
Bt.4902.1.S1_at
GO:0003824
GO:0006508
GO:0008234
GO:0016787
GO:0140096
Participates
as a member of
glycosylated LMAN cargo [COPII-coated ER to Golgi transport vesicle] (Bos taurus)
Other forms of this molecule
CTSZ [Golgi lumen]
CTSZ [lysosomal lumen]
CTSZ [plasma membrane]
CTSZ [specific granule lumen]
CTSZ [extracellular region]
CTSZ [ficolin-1-rich granule lumen]
CTSZ [endoplasmic reticulum-Golgi intermediate compartment membrane]
CTSZ [endoplasmic reticulum lumen]
Inferred From
(Glc)3(GlcNAc)2(Man)9-CTSZ [COPII-coated ER to Golgi transport vesicle]
(Homo sapiens)
Modified Residues
Name
N4-(N-acetylamino)glucosyl-L-asparagine (N-{alpha-Glc-(1->2)-alpha-Glc-(1->3)-alpha-Glc-(1->3)-alpha-Man-(1->2)-alpha-Man-(1->2)-alpha-Man-(1->3)-(alpha-Man-(1->2)-alpha-Man-(1->3)-(alpha-Man-(1->2)-alpha-Man-(1->6))-alpha-Man-(1->6))-beta-Man-(1->4)-beta-GlcNAc-(1->4)-beta-GlcNAc}-L-Asn residue (ChEBI:59084)) at unknown position
Modification
N-{alpha-Glc-(1->2)-alpha-Glc-(1->3)-alpha-Glc-(1->3)-alpha-Man-(1->2)-alpha-Man-(1->2)-alpha-Man-(1->3)-(alpha-Man-(1->2)-alpha-Man-(1->3)-(alpha-Man-(1->2)-alpha-Man-(1->6))-alpha-Man-(1->6))-beta-Man-(1->4)-beta-GlcNAc-(1->4)-beta-GlcNAc}-yl group (ChEBI:59084)
PsiMod Name
N4-(N-acetylamino)glucosyl-L-asparagine
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.
Cross References
RefSeq
NP_001071303.1
OpenTargets
ENSG00000101160
Ensembl
ENSBTAG00000018784
,
ENSBTAP00000025007
,
ENSBTAT00000025007
VGNC
27820
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