Reactome | ARFGAP3 [cytosol]

ARFGAP3 [cytosol]

Stable Identifier

R-BTA-6807740

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

cytosol

Synonyms

ARFGAP3, Q17R07

Locations in the PathwayBrowser

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Metabolism of proteins (Bos taurus)

- Post-translational protein modification (Bos taurus)
  - Asparagine N-linked glycosylation (Bos taurus)
    - Transport to the Golgi and subsequent modification (Bos taurus)
      - ER to Golgi Anterograde Transport (Bos taurus)
        
        COPI-mediated anterograde transport (Bos taurus)
        
        ARFGAPs stimulate ARF GTPase activity (Bos taurus)
        
        ARFGAP1,2,3 [cytosol] (Bos taurus)
        
        ARFGAP3 [cytosol] (Bos taurus)
        
        RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer:ARFGAP1,2,3:PalmC-YKT6:p24 dimers:cargo:spectrin:ankyrin [endoplasmic reticulum-Golgi intermediate compartment membrane] (Bos taurus)
        
        ARFGAP1,2,3 [cytosol] (Bos taurus)
        
        ARFGAP3 [cytosol] (Bos taurus)

Signal Transduction (Bos taurus)

- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Bos taurus)
  - Signaling by Rho GTPases (Bos taurus)
    - RHO GTPase cycle (Bos taurus)
      - RHOG GTPase cycle (Bos taurus)
        
        RHOG binds effectors at the plasma membrane (Bos taurus)
        
        RHOG plasma membrane effectors [cytosol] (Bos taurus)
        
        ARFGAP3 [cytosol] (Bos taurus)
        
        RHOG:GTP:RHOG plasma membrane effectors [plasma membrane] (Bos taurus)
        
        RHOG plasma membrane effectors [cytosol] (Bos taurus)
        
        ARFGAP3 [cytosol] (Bos taurus)

External Reference Information

External Reference

UniProt:Q17R07

Gene Names

ARFGAP3

Reference Genes

BioGPS Gene:532778 ARFGAP3

ENSEMBL:ENSBTAG00000001057

ENSEMBL:ENSBTAG00000001057.6 ARFGAP3

KEGG Gene (Bos taurus):532778 ARFGAP3

Monarch:532778 ARFGAP3

NCBI Gene:532778 ARFGAP3

Reference Transcript

RefSeq:NM_001075974.1 ARFGAP3

Other Identifiers

532778

GO:0000139

GO:0005096

GO:0005737

GO:0005794

GO:0015031

GO:0016020

GO:0016192

GO:0043226

GO:0046872

GO:0048205

GO:0061024

GO:0098772

Participates

as a candidate of

as a member of

ARFGAP1,2,3 [cytosol] (Bos taurus)

Inferred From

ARFGAP3 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001069442.1

OpenTargets

ENSG00000242247

Ensembl

ENSBTAP00000050747, ENSBTAT00000053995, ENSBTAG00000001057

VGNC

26063