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RPS2 [cytosol]
Stable Identifier
R-BTA-72347
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
cytosol
Synonyms
RPS2, A0A452DIA7
Locations in the PathwayBrowser
Expand all
Chromatin organization (Bos taurus)
Chromatin modifying enzymes (Bos taurus)
RMTs methylate histone arginines (Bos taurus)
PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2 (Bos taurus)
RPS2 [cytosol] (Bos taurus)
Metabolism of RNA (Bos taurus)
Nonsense-Mediated Decay (NMD) (Bos taurus)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Bos taurus)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Bos taurus)
SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Bos taurus)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Bos taurus)
80S ribosome [cytosol] (Bos taurus)
40S ribosomal complex [cytosol] (Bos taurus)
RPS2 [cytosol] (Bos taurus)
SMG1:UPF1:EJC:Translated mRNP [cytosol] (Bos taurus)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Bos taurus)
80S ribosome [cytosol] (Bos taurus)
40S ribosomal complex [cytosol] (Bos taurus)
RPS2 [cytosol] (Bos taurus)
SMG6 hydrolyzes mRNA with premature termination codon (Bos taurus)
Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Bos taurus)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Bos taurus)
80S ribosome [cytosol] (Bos taurus)
40S ribosomal complex [cytosol] (Bos taurus)
RPS2 [cytosol] (Bos taurus)
UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex (Bos taurus)
SMG1:UPF1:EJC:Translated mRNP [cytosol] (Bos taurus)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Bos taurus)
80S ribosome [cytosol] (Bos taurus)
40S ribosomal complex [cytosol] (Bos taurus)
RPS2 [cytosol] (Bos taurus)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Bos taurus)
80S ribosome [cytosol] (Bos taurus)
40S ribosomal complex [cytosol] (Bos taurus)
RPS2 [cytosol] (Bos taurus)
p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A (Bos taurus)
Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Bos taurus)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Bos taurus)
80S ribosome [cytosol] (Bos taurus)
40S ribosomal complex [cytosol] (Bos taurus)
RPS2 [cytosol] (Bos taurus)
SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Bos taurus)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Bos taurus)
80S ribosome [cytosol] (Bos taurus)
40S ribosomal complex [cytosol] (Bos taurus)
RPS2 [cytosol] (Bos taurus)
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Bos taurus)
Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Bos taurus)
Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Bos taurus)
80S ribosome [cytosol] (Bos taurus)
40S ribosomal complex [cytosol] (Bos taurus)
RPS2 [cytosol] (Bos taurus)
UPF1:eRF3 Complex on Translated mRNA [cytosol] (Bos taurus)
Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Bos taurus)
80S ribosome [cytosol] (Bos taurus)
40S ribosomal complex [cytosol] (Bos taurus)
RPS2 [cytosol] (Bos taurus)
rRNA processing (Bos taurus)
rRNA processing in the nucleus and cytosol (Bos taurus)
Major pathway of rRNA processing in the nucleolus and cytosol (Bos taurus)
18SE pre-rRNA in pre-40S particles is nucleolytically processed during translocation from the nucleus to the cytosol (Bos taurus)
40S ribosomal complex [cytosol] (Bos taurus)
RPS2 [cytosol] (Bos taurus)
30S pre-rRNA is nucleolytically processed at site 1 to yield 21S pre-rRNA (Bos taurus)
RPS2 [cytosol] (Bos taurus)
Metabolism of proteins (Bos taurus)
Post-translational protein modification (Bos taurus)
Protein methylation (Bos taurus)
PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2 (Bos taurus)
RPS2 [cytosol] (Bos taurus)
Translation (Bos taurus)
Eukaryotic Translation Initiation (Bos taurus)
Cap-dependent Translation Initiation (Bos taurus)
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S (Bos taurus)
Translation initiation complex formation (Bos taurus)
Formation of translation initiation complexes containing mRNA that does not circularize (Bos taurus)
43S complex [cytosol] (Bos taurus)
40S ribosomal complex [cytosol] (Bos taurus)
RPS2 [cytosol] (Bos taurus)
48S complex [cytosol] (Bos taurus)
43S complex [cytosol] (Bos taurus)
40S ribosomal complex [cytosol] (Bos taurus)
RPS2 [cytosol] (Bos taurus)
Formation of translation initiation complexes yielding circularized Ceruloplasmin mRNA in a 'closed-loop' conformation (Bos taurus)
43S complex [cytosol] (Bos taurus)
40S ribosomal complex [cytosol] (Bos taurus)
RPS2 [cytosol] (Bos taurus)
43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP [cytosol] (Bos taurus)
43S complex [cytosol] (Bos taurus)
40S ribosomal complex [cytosol] (Bos taurus)
RPS2 [cytosol] (Bos taurus)
Formation of a pool of free 40S subunits (Bos taurus)
Release of 40S and 60S subunits from the 80S ribosome (Bos taurus)
40S ribosomal complex [cytosol] (Bos taurus)
RPS2 [cytosol] (Bos taurus)
80S ribosome [cytosol] (Bos taurus)
40S ribosomal complex [cytosol] (Bos taurus)
RPS2 [cytosol] (Bos taurus)
eIF3 and eIF1A bind to the 40S subunit (Bos taurus)
40S ribosomal complex [cytosol] (Bos taurus)
RPS2 [cytosol] (Bos taurus)
40S:eIF3:eIF1A [cytosol] (Bos taurus)
40S ribosomal complex [cytosol] (Bos taurus)
RPS2 [cytosol] (Bos taurus)
Formation of the ternary complex, and subsequently, the 43S complex (Bos taurus)
Formation of the 43S pre-initiation complex (Bos taurus)
40S:eIF3:eIF1A [cytosol] (Bos taurus)
40S ribosomal complex [cytosol] (Bos taurus)
RPS2 [cytosol] (Bos taurus)
43S complex [cytosol] (Bos taurus)
40S ribosomal complex [cytosol] (Bos taurus)
RPS2 [cytosol] (Bos taurus)
GTP hydrolysis and joining of the 60S ribosomal subunit (Bos taurus)
The 60S subunit joins the translation initiation complex (Bos taurus)
40S:Met-tRNAi:mRNA [cytosol] (Bos taurus)
40S ribosomal complex [cytosol] (Bos taurus)
RPS2 [cytosol] (Bos taurus)
80S:Met-tRNAi:mRNA:eIF5B:GTP [cytosol] (Bos taurus)
80S ribosome [cytosol] (Bos taurus)
40S ribosomal complex [cytosol] (Bos taurus)
RPS2 [cytosol] (Bos taurus)
eIF5B:GTP is hydrolyzed and released (Bos taurus)
80S:Met-tRNAi:mRNA [cytosol] (Bos taurus)
80S ribosome [cytosol] (Bos taurus)
40S ribosomal complex [cytosol] (Bos taurus)
RPS2 [cytosol] (Bos taurus)
80S:Met-tRNAi:mRNA:eIF5B:GTP [cytosol] (Bos taurus)
80S ribosome [cytosol] (Bos taurus)
40S ribosomal complex [cytosol] (Bos taurus)
RPS2 [cytosol] (Bos taurus)
Ribosomal scanning and start codon recognition (Bos taurus)
Ribosomal scanning (Bos taurus)
48S complex [cytosol] (Bos taurus)
43S complex [cytosol] (Bos taurus)
40S ribosomal complex [cytosol] (Bos taurus)
RPS2 [cytosol] (Bos taurus)
Start codon recognition (Bos taurus)
48S complex [cytosol] (Bos taurus)
43S complex [cytosol] (Bos taurus)
40S ribosomal complex [cytosol] (Bos taurus)
RPS2 [cytosol] (Bos taurus)
L13a-mediated translational silencing of Ceruloplasmin expression (Bos taurus)
Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA (Bos taurus)
43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP [cytosol] (Bos taurus)
43S complex [cytosol] (Bos taurus)
40S ribosomal complex [cytosol] (Bos taurus)
RPS2 [cytosol] (Bos taurus)
phospho-L13a associated wth the 3' UTR GAIT element of ceruloplasmin mRNA within the translation initiation complex [cytosol] (Bos taurus)
43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP [cytosol] (Bos taurus)
43S complex [cytosol] (Bos taurus)
40S ribosomal complex [cytosol] (Bos taurus)
RPS2 [cytosol] (Bos taurus)
SRP-dependent cotranslational protein targeting to membrane (Bos taurus)
Nascent polypeptide:mRNA:ribosome complex binds signal recognition particle (SRP) (Bos taurus)
SRP:polypeptide+signal:ribosome [cytosol] (Bos taurus)
ribosome:mRNA:polypeptide+signal [cytosol] (Bos taurus)
80S ribosome [cytosol] (Bos taurus)
40S ribosomal complex [cytosol] (Bos taurus)
RPS2 [cytosol] (Bos taurus)
ribosome:mRNA:polypeptide+signal [cytosol] (Bos taurus)
80S ribosome [cytosol] (Bos taurus)
40S ribosomal complex [cytosol] (Bos taurus)
RPS2 [cytosol] (Bos taurus)
External Reference Information
External Reference
UniProt:A0A452DIA7
Gene Names
RPS2
Reference Genes
ENSEMBL:ENSBTAG00000009535.6
ENSEMBL:ENSBTAG00000009535.7 RPS2
Other Identifiers
GO:0003723
GO:0003735
GO:0005198
GO:0005829
GO:0005840
GO:0006412
GO:0015935
GO:0022626
GO:0022627
GO:0043226
GO:1990904
Participates
as an input of
PRMT3 transfers 3xCH3 from 3xAdoMet to RPS2 (Bos taurus)
as a component of
40S ribosomal complex [cytosol] (Bos taurus)
This entity regulates
Positively
30S pre-rRNA is nucleolytically processed at site 1 to yield 21S pre-rRNA
(Bos taurus)
Other forms of this molecule
RPS2 [nucleoplasm]
RPS2 [cytosol]
Inferred From
RPS2 [cytosol]
(Homo sapiens)
Cross References
OpenTargets
ENSG00000140988
Ensembl
ENSBTAT00000012544
,
ENSBTAP00000012544
,
ENSBTAG00000009535
VGNC
56750
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