Reactome | SHC1 [cytosol]

SHC1 [cytosol]

Stable Identifier

R-BTA-74680

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

cytosol

Synonyms

SHC1, Q0IIE2

Locations in the PathwayBrowser

Expand all

Immune System (Bos taurus)

- Cytokine Signaling in Immune system (Bos taurus)
  - Signaling by Interleukins (Bos taurus)
    - Interleukin-3, Interleukin-5 and GM-CSF signaling (Bos taurus)
      - Recruitment of SHC1 is mediated by Y593 of the common beta chain (Bos taurus)
        
        High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)-Bc:SHC1 [plasma membrane] (Bos taurus)
        
        High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:SHC1 [plasma membrane] (Bos taurus)
        
        SHC1 [cytosol] (Bos taurus)
        
        IL3:IL3R active complex, inactive JAK2, phosphorylated Bc:SHC1 [plasma membrane] (Bos taurus)
        
        SHC1 [cytosol] (Bos taurus)
        
        SHC1 [cytosol] (Bos taurus)

External Reference Information

External Reference

UniProt:Q0IIE2

Gene Names

SHC1

Reference Genes

BioGPS Gene:507196 SHC1

ENSEMBL:ENSBTAG00000019838

KEGG Gene (Bos taurus):507196 SHC1

Monarch:507196 SHC1

NCBI Gene:507196 SHC1

Reference Transcript

Other Identifiers

507196

Bt.18486.1.A1_at

Bt.4279.1.S1_at

Bt.4279.2.S1_at

Bt.4279.3.S1_a_at

GO:0001525

GO:0003674

GO:0007165

GO:0008150

GO:0019899

GO:0030971

GO:0035556

GO:0048646

GO:0048856

Participates

as a component of

as an input of

Other forms of this molecule

phospho-SHC1 [cytosol]

SHC1 [cytosol]

phospho-SHC1 [cytosol]

phospho-SHC1 [plasma membrane]

phospho-SHC1 [cytosol]

Inferred From

SHC1 [cytosol] (Homo sapiens)

SHC1-1 [cytosol] (Homo sapiens)

SHC1 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001157533.1, NP_001068773.1

OpenTargets

ENSG00000160691

Ensembl

ENSBTAT00000040264, ENSBTAG00000019838, ENSBTAT00000075224, ENSBTAP00000040041, ENSBTAP00000062285

VGNC

34590