Reactome | THOC6 [nucleoplasm]

THOC6 [nucleoplasm]

Stable Identifier

R-BTA-8849144

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

nucleoplasm

Synonyms

THOC6, A0A3Q1NKV3

Locations in the PathwayBrowser

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Gene expression (Transcription) (Bos taurus)

- RNA Polymerase II Transcription (Bos taurus)
  - RNA Polymerase II Transcription Termination (Bos taurus)
    - Cleavage of mRNA at the 3'-end (Bos taurus)
      - 3' end cleaved, ligated exon containing complex [nucleoplasm] (Bos taurus)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Bos taurus)
        
        THO complex [nucleoplasm] (Bos taurus)
        
        THOC6 [nucleoplasm] (Bos taurus)
      - Spliced mRNA:CBC:EJC:TREX [nucleoplasm] (Bos taurus)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Bos taurus)
        
        THO complex [nucleoplasm] (Bos taurus)
        
        THOC6 [nucleoplasm] (Bos taurus)

Metabolism of RNA (Bos taurus)

- Processing of Capped Intron-Containing Pre-mRNA (Bos taurus)
  - Transport of Mature Transcript to Cytoplasm (Bos taurus)
    - Transport of Mature mRNA derived from an Intron-Containing Transcript (Bos taurus)
      - NXF1:NXT1 (TAP:p15) binds capped mRNA:CBC:EJC:TREX (minus DDX39B) (Bos taurus)
        
        NXF1,2:NXT1::polyadenylated, capped mRNA:CBC:EJC:TREX:SRSF proteins [nucleoplasm] (Bos taurus)
        
        capped mRNA:CBC:EJC:TREX (minus DDX39B) [nucleoplasm] (Bos taurus)
        
        TREX (minus DDX39B) [nucleoplasm] (Bos taurus)
        
        THO complex [nucleoplasm] (Bos taurus)
        
        THOC6 [nucleoplasm] (Bos taurus)
        
        polyadenylated, capped mRNA:CBC:EJC:TREX:SRSF proteins [nucleoplasm] (Bos taurus)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Bos taurus)
        
        THO complex [nucleoplasm] (Bos taurus)
        
        THOC6 [nucleoplasm] (Bos taurus)
  - mRNA 3'-end processing (Bos taurus)
    - Cleavage of mRNA at the 3'-end (Bos taurus)
      - 3' end cleaved, ligated exon containing complex [nucleoplasm] (Bos taurus)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Bos taurus)
        
        THO complex [nucleoplasm] (Bos taurus)
        
        THOC6 [nucleoplasm] (Bos taurus)
      - Spliced mRNA:CBC:EJC:TREX [nucleoplasm] (Bos taurus)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Bos taurus)
        
        THO complex [nucleoplasm] (Bos taurus)
        
        THOC6 [nucleoplasm] (Bos taurus)
    - mRNA polyadenylation (Bos taurus)
      - 3' end cleaved, ligated exon containing complex [nucleoplasm] (Bos taurus)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Bos taurus)
        
        THO complex [nucleoplasm] (Bos taurus)
        
        THOC6 [nucleoplasm] (Bos taurus)
      - polyadenylated, capped mRNA:CBC:EJC:TREX:SRSF proteins [nucleoplasm] (Bos taurus)
        
        TREX (DDX39B:ATP) [nucleoplasm] (Bos taurus)
        
        THO complex [nucleoplasm] (Bos taurus)
        
        THOC6 [nucleoplasm] (Bos taurus)

External Reference Information

External Reference

UniProt:A0A3Q1NKV3

Gene Names

THOC6

Reference Genes

ENSEMBL:ENSBTAG00000001415.5

Participates

as a component of

THO complex [nucleoplasm] (Bos taurus)

Inferred From

THOC6 [nucleoplasm] (Homo sapiens)

Cross References

OpenTargets

ENSG00000131652

VGNC

35842

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