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RNF7 [cytosol]
Stable Identifier
R-BTA-8863132
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
cytosol
Synonyms
RNF7 (RBX2), Q0P5F4
Locations in the PathwayBrowser
Expand all
Immune System (Bos taurus)
Adaptive Immune System (Bos taurus)
Class I MHC mediated antigen processing & presentation (Bos taurus)
Antigen processing: Ubiquitination & Proteasome degradation (Bos taurus)
Interaction of E3 with substrate and E2-Ub complex (Bos taurus)
Ag-substrate:E3:E2:Ub [cytosol] (Bos taurus)
E3 ligases in proteasomal degradation [cytosol] (Bos taurus)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Bos taurus)
RNF7 [cytosol] (Bos taurus)
E3 ligases in proteasomal degradation [cytosol] (Bos taurus)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Bos taurus)
RNF7 [cytosol] (Bos taurus)
Polyubiquitination of substrate (Bos taurus)
E3 ligases in proteasomal degradation [cytosol] (Bos taurus)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Bos taurus)
RNF7 [cytosol] (Bos taurus)
E3:K48-polyubiquitinated substrate [cytosol] (Bos taurus)
E3 ligases in proteasomal degradation [cytosol] (Bos taurus)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Bos taurus)
RNF7 [cytosol] (Bos taurus)
E3:Ub:substrate [cytosol] (Bos taurus)
E3 ligases in proteasomal degradation [cytosol] (Bos taurus)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Bos taurus)
RNF7 [cytosol] (Bos taurus)
Release of E3 from polyubiquitinated substrate (Bos taurus)
E3 ligases in proteasomal degradation [cytosol] (Bos taurus)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Bos taurus)
RNF7 [cytosol] (Bos taurus)
E3:K48-polyubiquitinated substrate [cytosol] (Bos taurus)
E3 ligases in proteasomal degradation [cytosol] (Bos taurus)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Bos taurus)
RNF7 [cytosol] (Bos taurus)
Transfer of Ub from E2 to substrate and release of E2 (Bos taurus)
Ag-substrate:E3:E2:Ub [cytosol] (Bos taurus)
E3 ligases in proteasomal degradation [cytosol] (Bos taurus)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Bos taurus)
RNF7 [cytosol] (Bos taurus)
E3 ligases in proteasomal degradation [cytosol] (Bos taurus)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Bos taurus)
RNF7 [cytosol] (Bos taurus)
E3:Ub:substrate [cytosol] (Bos taurus)
E3 ligases in proteasomal degradation [cytosol] (Bos taurus)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Bos taurus)
RNF7 [cytosol] (Bos taurus)
Cytokine Signaling in Immune system (Bos taurus)
Signaling by CSF3 (G-CSF) (Bos taurus)
Inactivation of CSF3 (G-CSF) signaling (Bos taurus)
SOCS1,3 ubiquitinates CSF3R in SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:CUL5:ELOB:ELOC:RNF7 (Bos taurus)
RNF7 [cytosol] (Bos taurus)
SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:CUL5:ELOB:ELOC:RNF7 [endocytic vesicle membrane] (Bos taurus)
RNF7 [cytosol] (Bos taurus)
Metabolism of proteins (Bos taurus)
Post-translational protein modification (Bos taurus)
Neddylation (Bos taurus)
AcM-UBE2F transfers NEDD8 to CRL5 E3 ubiquitin ligase complex (Bos taurus)
NEDD8-AcM-UBE2F:CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Bos taurus)
CRL5 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Bos taurus)
CRL5 E3 ubiquitin ligase [cytosol] (Bos taurus)
RNF7 [cytosol] (Bos taurus)
NEDD8-CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Bos taurus)
NEDD8-CRL5 E3 ligase [cytosol] (Bos taurus)
RNF7 [cytosol] (Bos taurus)
RNF7 [cytosol] (Bos taurus)
CAND1 binds cytosolic CRL E3 ubiquitin ligases (Bos taurus)
CRL E3 ubiquitin ligase:CAND1 [cytosol] (Bos taurus)
CRL E3 ubiquitin ligases [cytosol] (Bos taurus)
CRL5 E3 ubiquitin ligase [cytosol] (Bos taurus)
RNF7 [cytosol] (Bos taurus)
CRL E3 ubiquitin ligases [cytosol] (Bos taurus)
CRL5 E3 ubiquitin ligase [cytosol] (Bos taurus)
RNF7 [cytosol] (Bos taurus)
COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes (Bos taurus)
CRL E3 ubiquitin ligase:CAND1 [cytosol] (Bos taurus)
CRL E3 ubiquitin ligases [cytosol] (Bos taurus)
CRL5 E3 ubiquitin ligase [cytosol] (Bos taurus)
RNF7 [cytosol] (Bos taurus)
CRL E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Bos taurus)
CRL5 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Bos taurus)
CRL5 E3 ubiquitin ligase [cytosol] (Bos taurus)
RNF7 [cytosol] (Bos taurus)
COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes (Bos taurus)
CRL E3 ubiquitin ligase complex:COMMDs:CCDC22:DCUN1Ds [cytosol] (Bos taurus)
CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Bos taurus)
CRL5 E3 ubiquitin ligase [cytosol] (Bos taurus)
RNF7 [cytosol] (Bos taurus)
NEDD8 CRL E3 ubiquitin ligases:COMMDs:CCDC22:DCUN1Ds [cytosol] (Bos taurus)
NEDD8-CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Bos taurus)
NEDD8-CRL5 E3 ligase [cytosol] (Bos taurus)
RNF7 [cytosol] (Bos taurus)
NEDD8:AcM-UBE2F binds CRL5 E3 ubiquitin ligase complex (Bos taurus)
CRL5 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Bos taurus)
CRL5 E3 ubiquitin ligase [cytosol] (Bos taurus)
RNF7 [cytosol] (Bos taurus)
NEDD8-AcM-UBE2F:CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Bos taurus)
CRL5 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Bos taurus)
CRL5 E3 ubiquitin ligase [cytosol] (Bos taurus)
RNF7 [cytosol] (Bos taurus)
External Reference Information
External Reference
UniProt:Q0P5F4
Gene Names
RNF7
Reference Genes
BioGPS Gene:515595 RNF7
ENSEMBL:ENSBTAG00000002185.5
ENSEMBL:ENSBTAG00000002185.6 RNF7
KEGG Gene (Bos taurus):515595 RNF7
Monarch:515595 RNF7
NCBI Gene:515595 RNF7
Reference Transcript
RefSeq:NM_001075720.2 RNF7
Other Identifiers
515595
Participates
as an output of
SOCS1,3 ubiquitinates CSF3R in SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:CUL5:ELOB:ELOC:RNF7 (Bos taurus)
as a component of
SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:CUL5:ELOB:ELOC:RNF7 [endocytic vesicle membrane] (Bos taurus)
CRL5 E3 ubiquitin ligase [cytosol] (Bos taurus)
NEDD8-CRL5 E3 ligase [cytosol] (Bos taurus)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Bos taurus)
Inferred From
RNF7 (RBX2) [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001069188.1
OpenTargets
ENSG00000114125
Ensembl
ENSBTAP00000002831
,
ENSBTAG00000002185
,
ENSBTAT00000002831
VGNC
34072
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