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E3 ligases in proteasomal degradation [cytosol]
Stable Identifier
R-BTA-976075
Type
Set [CandidateSet]
Species
Bos taurus
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Immune System (Bos taurus)
Adaptive Immune System (Bos taurus)
Class I MHC mediated antigen processing & presentation (Bos taurus)
Antigen processing: Ubiquitination & Proteasome degradation (Bos taurus)
Interaction of E3 with substrate and E2-Ub complex (Bos taurus)
Ag-substrate:E3:E2:Ub [cytosol] (Bos taurus)
E3 ligases in proteasomal degradation [cytosol] (Bos taurus)
E3 ligases in proteasomal degradation [cytosol] (Bos taurus)
Polyubiquitination of substrate (Bos taurus)
E3 ligases in proteasomal degradation [cytosol] (Bos taurus)
E3:K48-polyubiquitinated substrate [cytosol] (Bos taurus)
E3 ligases in proteasomal degradation [cytosol] (Bos taurus)
E3:Ub:substrate [cytosol] (Bos taurus)
E3 ligases in proteasomal degradation [cytosol] (Bos taurus)
Release of E3 from polyubiquitinated substrate (Bos taurus)
E3 ligases in proteasomal degradation [cytosol] (Bos taurus)
E3:K48-polyubiquitinated substrate [cytosol] (Bos taurus)
E3 ligases in proteasomal degradation [cytosol] (Bos taurus)
Transfer of Ub from E2 to substrate and release of E2 (Bos taurus)
Ag-substrate:E3:E2:Ub [cytosol] (Bos taurus)
E3 ligases in proteasomal degradation [cytosol] (Bos taurus)
E3 ligases in proteasomal degradation [cytosol] (Bos taurus)
E3:Ub:substrate [cytosol] (Bos taurus)
E3 ligases in proteasomal degradation [cytosol] (Bos taurus)
Participants
members
CUL1 [cytosol]
(Bos taurus)
RNF144B [cytosol]
(Bos taurus)
RNF19B [cytosol]
(Bos taurus)
MIB2 [cytosol]
(Bos taurus)
NEDD4L [cytosol]
(Bos taurus)
SIAH1 [cytosol]
(Bos taurus)
SPSB1 [cytosol]
(Bos taurus)
TRIP12 [cytosol]
(Bos taurus)
DTX3L [cytosol]
(Bos taurus)
HERC5 [cytosol]
(Bos taurus)
RBCK1 [cytosol]
(Bos taurus)
SIAH2 [cytosol]
(Bos taurus)
TRIM21 [cytosol]
(Bos taurus)
TRIM69 [cytosol]
(Bos taurus)
UBR2 [cytosol]
(Bos taurus)
HUWE1 [cytosol]
(Bos taurus)
SMURF2 [cytosol]
(Bos taurus)
TRIM36 [cytosol]
(Bos taurus)
WSB1 [cytosol]
(Bos taurus)
SCF E3 ubiquitin ligase [cytosol]
(Bos taurus)
LOC509283 [cytosol]
(Bos taurus)
HECTD2 [cytosol]
(Bos taurus)
LONRF1 [cytosol]
(Bos taurus)
RBBP6 [cytosol]
(Bos taurus)
RNF19A [cytosol]
(Bos taurus)
ZNRF1 [cytosol]
(Bos taurus)
HERC6 [cytosol]
(Bos taurus)
RNF217 [cytosol]
(Bos taurus)
RNF114 [cytosol]
(Bos taurus)
ZNRF2 [cytosol]
(Bos taurus)
FBXL4 [cytosol]
(Bos taurus)
RLIM [cytosol]
(Bos taurus)
RNF115 [cytosol]
(Bos taurus)
UNKL [cytosol]
(Bos taurus)
MYLIP [cytosol]
(Bos taurus)
candidates
CBLB [cytosol]
(Bos taurus)
STUB1 [cytosol]
(Bos taurus)
DZIP3 [cytosol]
(Bos taurus)
HECTD3 [cytosol]
(Bos taurus)
HERC2 [cytosol]
(Bos taurus)
ITCH [cytosol]
(Bos taurus)
LRSAM1 [cytosol]
(Bos taurus)
MGRN1 [cytosol]
(Bos taurus)
NEDD4 [cytosol]
(Bos taurus)
RNF182 [cytosol]
(Bos taurus)
RNF220 [cytosol]
(Bos taurus)
RNF25 [cytosol]
(Bos taurus)
RNF6 [cytosol]
(Bos taurus)
SMURF1 [cytosol]
(Bos taurus)
TRIM11 [cytosol]
(Bos taurus)
TRIM32 [cytosol]
(Bos taurus)
TRIM37 [cytosol]
(Bos taurus)
TRIM63 [cytosol]
(Bos taurus)
TRIM9 [cytosol]
(Bos taurus)
UBR1 [cytosol]
(Bos taurus)
GAN [cytosol]
(Bos taurus)
WWP1 [cytosol]
(Bos taurus)
RCHY1 [cytosol]
(Bos taurus)
SPSB2 [cytosol]
(Bos taurus)
SPSB4 [cytosol]
(Bos taurus)
UBOX5 [cytosol]
(Bos taurus)
UBE4A [cytosol]
(Bos taurus)
UBE3A [cytosol]
(Bos taurus)
UBE3B [cytosol]
(Bos taurus)
UBE3C [cytosol]
(Bos taurus)
RBX1-CUL2-EloB,C-VHL [cytosol]
(Bos taurus)
RBX1:CUL3:BTB [cytosol]
(Bos taurus)
RBX1:CUL5:EloB/C:LRRC41 [cytosol]
(Bos taurus)
RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol]
(Bos taurus)
RBX1-CUL5-EloB/C-SOCS [cytosol]
(Bos taurus)
RBX1:CUL7:SKP1:FBXW8:GLMN [cytosol]
(Bos taurus)
APC/C E3 ligase complex [cytosol]
(Bos taurus)
UBR4 [cytosol]
(Bos taurus)
LRRC41 [cytosol]
(Bos taurus)
RNF41 [cytosol]
(Bos taurus)
PJA2 [cytosol]
(Bos taurus)
RNF123 [cytosol]
(Bos taurus)
PJA1 [cytosol]
(Bos taurus)
PRKN [cytosol]
(Bos taurus)
RNF34 [cytosol]
(Bos taurus)
LOC789309 [cytosol]
(Bos taurus)
FBXO44 [cytosol]
(Bos taurus)
RNF4 [cytosol]
(Bos taurus)
ARIH2 [cytosol]
(Bos taurus)
RNF138 [cytosol]
(Bos taurus)
MKRN1 [cytosol]
(Bos taurus)
LRR1 [cytosol]
(Bos taurus)
RNF111 [cytosol]
(Bos taurus)
DCAF1 [cytosol]
(Bos taurus)
DET1 [cytosol]
(Bos taurus)
HECTD1 [cytosol]
(Bos taurus)
LTN1 [cytosol]
(Bos taurus)
RNF14 [cytosol]
(Bos taurus)
SH3RF1 [cytosol]
(Bos taurus)
TRIM39 [cytosol]
(Bos taurus)
TRIM41 [cytosol]
(Bos taurus)
TRIM50 [cytosol]
(Bos taurus)
TRIM71 [cytosol]
(Bos taurus)
UFL1 [cytosol]
(Bos taurus)
AREL1 [cytosol]
(Bos taurus)
BTBD1 [cytosol]
(Bos taurus)
HACE1 [cytosol]
(Bos taurus)
HECW2 [cytosol]
(Bos taurus)
HERC3 [cytosol]
(Bos taurus)
HERC4 [cytosol]
(Bos taurus)
KLHL11 [cytosol]
(Bos taurus)
LNX1 [cytosol]
(Bos taurus)
MEX3C [cytosol]
(Bos taurus)
RNF126 [cytosol]
(Bos taurus)
RNF130 [cytosol]
(Bos taurus)
TRAIP [cytosol]
(Bos taurus)
TRIM4 [cytosol]
(Bos taurus)
UBAC1 [cytosol]
(Bos taurus)
UBE3D [cytosol]
(Bos taurus)
CBLL1 [cytosol]
(Bos taurus)
Participates
as a component of
Ag-substrate:E3:E2:Ub [cytosol] (Bos taurus)
E3:Ub:substrate [cytosol] (Bos taurus)
E3:K48-polyubiquitinated substrate [cytosol] (Bos taurus)
as an input of
Interaction of E3 with substrate and E2-Ub complex (Bos taurus)
as an output of
Release of E3 from polyubiquitinated substrate (Bos taurus)
Inferred From
E3 ligases in proteasomal degradation [cytosol]
(Homo sapiens)
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