Reactome | phospho-p-T185,Y187-MAPK1 [cytosol]

phospho-p-T185,Y187-MAPK1 [cytosol]

Stable Identifier

R-CEL-109853

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

cytosol

Synonyms

P39745

Locations in the PathwayBrowser

Expand all

Cell Cycle (Caenorhabditis elegans)

- Cell Cycle, Mitotic (Caenorhabditis elegans)
  - M Phase (Caenorhabditis elegans)
    - Mitotic Prophase (Caenorhabditis elegans)
      - Golgi Cisternae Pericentriolar Stack Reorganization (Caenorhabditis elegans)
        
        MAPK3-3 or MAPK1 phosphorylate GORASP2 (Caenorhabditis elegans)
        
        p-Y204-MAPK3-3/p-T185,Y187-MAPK1 homodimer [cytosol] (Caenorhabditis elegans)
        
        p-T185,Y187 MAPK1 dimer [cytosol] (Caenorhabditis elegans)
        
        phospho-p-T185,Y187-MAPK1 [cytosol] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:P39745

Reference Genes

BioGPS Gene:175545

CTD Gene:175545

ENSEMBL:WBGene00003401

KEGG:cel:CELE_F43C1.2

Monarch:175545

NCBI Entrez Gene:175545

UCSC:P39745

Wormbase:WBGene00003401

Reference Transcript

Other Identifiers

175545

GO:0000165

GO:0000166

GO:0001556

GO:0002164

GO:0003006

GO:0003824

GO:0004672

GO:0004674

GO:0004707

GO:0005515

GO:0005524

GO:0005634

GO:0005737

GO:0006355

GO:0006468

GO:0007166

GO:0007265

GO:0016301

GO:0016740

GO:0022412

GO:0022414

GO:0030154

GO:0032436

GO:0035556

GO:0040025

GO:0045944

GO:0046872

GO:0048468

GO:0048477

GO:0048513

GO:0048856

GO:0050830

GO:0051321

GO:0098542

GO:0106310

GO:0140096

Participates

as an input of

Phosphorylation of L1 by ERK (Caenorhabditis elegans)

as a component of

as an output of

Dissociation of p-T,Y-MAPK1:p-S,T-MAP2K2 (Caenorhabditis elegans)

as a member of

p-T,Y MAPKs [cytosol] (Caenorhabditis elegans)

Other forms of this molecule

MAPK1 [ficolin-1-rich granule lumen]

MAPK1 [extracellular region]

MAPK1 [azurophil granule lumen]

phospho-p-Y204-MAPK3-3 [cytosol]

MAPK1 [nucleoplasm]

MAPK3 [nucleoplasm]

MAPK3 [cytosol]

MAPK1 [cytosol]

phospho-p-T202,Y204-MAPK3 [cytosol]

phospho-p-T202,Y204-MAPK3 [nucleoplasm]

phospho-p-T185,Y187-MAPK1 [nucleoplasm]

Inferred From

p-T185,Y187-MAPK1 [cytosol] (Homo sapiens)

Modified Residues

Name

O-phospho-L-threonine at 185 (in Homo sapiens)

Coordinate

185

PsiMod Name

O-phospho-L-threonine [MOD:00047]

PsiMod Definition

A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.

Name

O4'-phospho-L-tyrosine at 187 (in Homo sapiens)

Coordinate

187

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Cross References

RefSeq

NP_001366708.1, NP_001022584.1, NP_001022583.1

ENSEMBL

WBGene00003401, F43C1.2b.1, F43C1.2b.1

PRO

P39745

Interactors (8)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O02289 O02289			0.621	3
UniProt:Q17695 SPDL1			0.553	2
UniProt:Q19203 UNC98			0.553	2
UniProt:W10D9.3 O17285			0.553	2
UniProt:P91820 LST1			0.553	2
UniProt:Q9XUF2 Q9XUF2			0.553	2
UniProt:Q21229 Q21229			0.553	2
UniProt:P91829	1	nhr-69 [nucleoplasm] (R-CEL-446162-8)	0.553	2

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