Reactome | his-40 [nucleoplasm]

his-40 [nucleoplasm]

Stable Identifier

R-CEL-1214170

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

nucleoplasm

Synonyms

Me2K5-HIST1H3A, K7ZUH9

Locations in the PathwayBrowser

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Gene expression (Transcription) (Caenorhabditis elegans)

- RNA Polymerase II Transcription (Caenorhabditis elegans)
  - Generic Transcription Pathway (Caenorhabditis elegans)
    - Transcriptional regulation by RUNX1 (Caenorhabditis elegans)
      - RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function (Caenorhabditis elegans)
        
        Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter (Caenorhabditis elegans)
        
        H3K4me2-Nucleosome:GP1BA gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Caenorhabditis elegans)
        
        Nucleosome with H3K4me2 [nucleoplasm] (Caenorhabditis elegans)
        
        Histone H3 (H3K4me2) [nucleoplasm] (Caenorhabditis elegans)
        
        Homologues of Me2K5-HIST1H3A [nucleoplasm] (Caenorhabditis elegans)
        
        his-40 [nucleoplasm] (Caenorhabditis elegans)
        
        Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter (Caenorhabditis elegans)
        
        H3K4me2-Nucleosome:ITGA2B gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Caenorhabditis elegans)
        
        Nucleosome with H3K4me2 [nucleoplasm] (Caenorhabditis elegans)
        
        Histone H3 (H3K4me2) [nucleoplasm] (Caenorhabditis elegans)
        
        Homologues of Me2K5-HIST1H3A [nucleoplasm] (Caenorhabditis elegans)
        
        his-40 [nucleoplasm] (Caenorhabditis elegans)
        
        Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter (Caenorhabditis elegans)
        
        H3K4me2-Nucleosome:MIR27A gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Caenorhabditis elegans)
        
        Nucleosome with H3K4me2 [nucleoplasm] (Caenorhabditis elegans)
        
        Histone H3 (H3K4me2) [nucleoplasm] (Caenorhabditis elegans)
        
        Homologues of Me2K5-HIST1H3A [nucleoplasm] (Caenorhabditis elegans)
        
        his-40 [nucleoplasm] (Caenorhabditis elegans)
        
        Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter (Caenorhabditis elegans)
        
        H3K4me2-Nucleosome:THBS1 gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Caenorhabditis elegans)
        
        Nucleosome with H3K4me2 [nucleoplasm] (Caenorhabditis elegans)
        
        Histone H3 (H3K4me2) [nucleoplasm] (Caenorhabditis elegans)
        
        Homologues of Me2K5-HIST1H3A [nucleoplasm] (Caenorhabditis elegans)
        
        his-40 [nucleoplasm] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:K7ZUH9

Gene Names

his-40

Reference Genes

BioGPS Gene:13221387 his-40

ENSEMBL:WBGene00001914

KEGG:cel:CELE_B0035.10 his-40

KEGG:cel:CELE_F07B7.5 his-40

KEGG:cel:CELE_F17E9.10 his-40

KEGG:cel:CELE_F22B3.2 his-40

KEGG:cel:CELE_F45F2.13 his-40

KEGG:cel:CELE_F54E12.1 his-40

KEGG:cel:CELE_F55G1.2 his-40

KEGG:cel:CELE_K03A1.1 his-40

KEGG:cel:CELE_K06C4.13 his-40

KEGG:cel:CELE_K06C4.5 his-40

KEGG:cel:CELE_T10C6.13 his-40

KEGG:cel:CELE_ZK131.2 his-40

KEGG:cel:CELE_ZK131.3 his-40

KEGG:cel:CELE_ZK131.7 his-40

Monarch:13221387 his-40

NCBI Gene:13221387 his-40

UCSC:K7ZUH9 his-40

Wormbase:WBGene00001914

Wormbase:WBGene00001914 his-40

Reference Transcript

Other Identifiers

13221387

175030

175031

177628

180074

181821

184113

184804

186250

186325

191668

191672

191673

246024

54161976

GO:0000786

GO:0003677

GO:0005198

GO:0005634

GO:0005694

GO:0030527

GO:0046982

Participates

as a member of

Homologues of Me2K5-HIST1H3A [nucleoplasm] (Caenorhabditis elegans)

Other forms of this molecule

his-40 [nucleoplasm]

his-40 [cytosol]

his-40 [nucleoplasm]

Inferred From

Me2K5-HIST1H3A [nucleoplasm] (Homo sapiens)

Modified Residues

Name

N6,N6-dimethyl-L-lysine at 5 (in Homo sapiens)

Coordinate

PsiMod Name

N6,N6-dimethyl-L-lysine [MOD:00084]

PsiMod Definition

A protein modification that effectively converts an L-lysine residue to N6,N6-dimethyl-L-lysine.

Cross References

RefSeq

NP_001263958.1, NP_496899.1

ENSEMBL

F17E9.10.1, K03A1.1.1, K06C4.5.1, B0035.10.1, F22B3.2.1, WBGene00001919, WBGene00001899, WBGene00001914, WBGene00001937, F45F2.13.1, WBGene00001933, ZK131.3.1, K06C4.13.1, ZK131.2.1, WBGene00001916, WBGene00001876, F08G2.3.1, F55G1.2.1, ZK131.7.1, F22B3.2.1, T10C6.13.1, F17E9.10.1, K03A1.1.1, ZK131.3.1, ZK131.2.1, F08G2.3.1, B0035.10.1, F55G1.2.1, WBGene00001880, F07B7.5.1, F45F2.13.1, ZK131.7.1, WBGene00001887, WBGene00001923, WBGene00001906, K06C4.13.1, WBGene00001929, F07B7.5.1, WBGene00001883, WBGene00001901, T10C6.13.1, F54E12.1.1, K06C4.5.1, WBGene00001891, F54E12.1.1