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ERBB2:ERBIN:HSP90:CDC37 [plasma membrane]
Stable Identifier
R-CEL-1227970
Type
Complex
Species
Caenorhabditis elegans
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Caenorhabditis elegans)
Signaling by Receptor Tyrosine Kinases (Caenorhabditis elegans)
Signaling by ERBB2 (Caenorhabditis elegans)
Downregulation of ERBB2 signaling (Caenorhabditis elegans)
CHIP (STUB1) mediates ubiquitination of ERBB2 (Caenorhabditis elegans)
ERBB2:ERBIN:HSP90:CDC37 [plasma membrane] (Caenorhabditis elegans)
CUL5 mediates ubiquitination of ERBB2 (Caenorhabditis elegans)
ERBB2:ERBIN:HSP90:CDC37 [plasma membrane] (Caenorhabditis elegans)
Drug-mediated inhibition of ERBB2 signaling (Caenorhabditis elegans)
ERBB2 binds TKIs (Caenorhabditis elegans)
ERBB2:ERBIN:HSP90:CDC37 [plasma membrane] (Caenorhabditis elegans)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
CDC37 [cytosol]
(Caenorhabditis elegans)
ERBB2 [plasma membrane]
(Caenorhabditis elegans)
Ghost homologue of ERBIN [plasma membrane]
(Caenorhabditis elegans)
HSP90 [cytosol]
(Caenorhabditis elegans)
Participates
as an input of
CUL5 mediates ubiquitination of ERBB2 (Caenorhabditis elegans)
CHIP (STUB1) mediates ubiquitination of ERBB2 (Caenorhabditis elegans)
ERBB2 binds TKIs (Caenorhabditis elegans)
Inferred From
ERBB2:ERBIN:HSP90:CDC37 [plasma membrane]
(Homo sapiens)
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