Reactome | rnp-5 [cytosol]

rnp-5 [cytosol]

Stable Identifier

R-CEL-159256

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

cytosol

Synonyms

RNPS1, Q21155

Locations in the PathwayBrowser

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Metabolism of RNA (Caenorhabditis elegans)

- Nonsense-Mediated Decay (NMD) (Caenorhabditis elegans)
  - Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Caenorhabditis elegans)
    - SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Caenorhabditis elegans)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Caenorhabditis elegans)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
        
        Exon Junction:UPF2:UPF3 Complex [cytosol] (Caenorhabditis elegans)
        
        rnp-5 [cytosol] (Caenorhabditis elegans)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Caenorhabditis elegans)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
        
        Exon Junction:UPF2:UPF3 Complex [cytosol] (Caenorhabditis elegans)
        
        rnp-5 [cytosol] (Caenorhabditis elegans)
    - SMG6 hydrolyzes mRNA with premature termination codon (Caenorhabditis elegans)
      - Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Caenorhabditis elegans)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
        
        Exon Junction:UPF2:UPF3 Complex [cytosol] (Caenorhabditis elegans)
        
        rnp-5 [cytosol] (Caenorhabditis elegans)
    - UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex (Caenorhabditis elegans)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Caenorhabditis elegans)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
        
        Exon Junction:UPF2:UPF3 Complex [cytosol] (Caenorhabditis elegans)
        
        rnp-5 [cytosol] (Caenorhabditis elegans)
      - Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
        
        Exon Junction:UPF2:UPF3 Complex [cytosol] (Caenorhabditis elegans)
        
        rnp-5 [cytosol] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:Q21155

Gene Names

rnp-5

Reference Genes

ENSEMBL:WBGene00004388

UCSC:Q21155 rnp-5

Wormbase:WBGene00004388

Reference Transcript

RefSeq:NM_064875.7 rnp-5

Other Identifiers

173179_s_at

175244

18525454

192011_s_at

A_12_P117345

CE29981

CE_WBGene00004388_A

CGZ0027460

GO:0003676

GO:0003723

K02F3.11

K02F3.11_426-485_0.897_14_B

K02F3.11_554-613_0.946_1_A

K02F3.11_665-724_0.926_5_C

K02F3_11P00204

K02F3_11P00598

K02F3_11P00783

cea2.c.21170

Participates

as a component of

Other forms of this molecule

rnp-5 [nucleoplasm]

Inferred From

RNPS1 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_497276.2

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