Reactome | rnp-4 [cytosol]

rnp-4 [cytosol]

Stable Identifier

R-CEL-162462

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

cytosol

Synonyms

RBM8A, Q21832

Locations in the PathwayBrowser

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Metabolism of RNA (Caenorhabditis elegans)

- Nonsense-Mediated Decay (NMD) (Caenorhabditis elegans)
  - Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Caenorhabditis elegans)
    - SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Caenorhabditis elegans)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Caenorhabditis elegans)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
        
        Exon Junction:UPF2:UPF3 Complex [cytosol] (Caenorhabditis elegans)
        
        Core Exon Junction Complex (Core EJC) [cytosol] (Caenorhabditis elegans)
        
        Magoh-Y14 complex [cytosol] (Caenorhabditis elegans)
        
        rnp-4 [cytosol] (Caenorhabditis elegans)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Caenorhabditis elegans)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
        
        Exon Junction:UPF2:UPF3 Complex [cytosol] (Caenorhabditis elegans)
        
        Core Exon Junction Complex (Core EJC) [cytosol] (Caenorhabditis elegans)
        
        Magoh-Y14 complex [cytosol] (Caenorhabditis elegans)
        
        rnp-4 [cytosol] (Caenorhabditis elegans)
    - SMG6 hydrolyzes mRNA with premature termination codon (Caenorhabditis elegans)
      - Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Caenorhabditis elegans)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
        
        Exon Junction:UPF2:UPF3 Complex [cytosol] (Caenorhabditis elegans)
        
        Core Exon Junction Complex (Core EJC) [cytosol] (Caenorhabditis elegans)
        
        Magoh-Y14 complex [cytosol] (Caenorhabditis elegans)
        
        rnp-4 [cytosol] (Caenorhabditis elegans)
    - UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex (Caenorhabditis elegans)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Caenorhabditis elegans)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
        
        Exon Junction:UPF2:UPF3 Complex [cytosol] (Caenorhabditis elegans)
        
        Core Exon Junction Complex (Core EJC) [cytosol] (Caenorhabditis elegans)
        
        Magoh-Y14 complex [cytosol] (Caenorhabditis elegans)
        
        rnp-4 [cytosol] (Caenorhabditis elegans)
      - Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
        
        Exon Junction:UPF2:UPF3 Complex [cytosol] (Caenorhabditis elegans)
        
        Core Exon Junction Complex (Core EJC) [cytosol] (Caenorhabditis elegans)
        
        Magoh-Y14 complex [cytosol] (Caenorhabditis elegans)
        
        rnp-4 [cytosol] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:Q21832

Gene Names

rnp-4

Reference Genes

ENSEMBL:WBGene00004387

UCSC:Q21832 rnp-4

Wormbase:WBGene00004387

Reference Transcript

RefSeq:NM_065490.4 rnp-4

Other Identifiers

173284_s_at

175572

18514442

189726_at

A_12_P109840

A_12_P146485

A_12_P146486

A_12_P146487

A_12_P146488

A_12_P171802

A_12_P171803

CE01044

CE_WBGene00004387_A

CE_WBGene00004387_B

CE_WBGene00004387_C

CGZ0031323

GO:0003676

GO:0003723

GO:0003729

GO:0005634

GO:0005737

GO:0006396

GO:0043226

R07E5.14

R07E5.14_163-222_0.919_6_C

R07E5.14_244-303_0.917_7_B

R07E5.14_358-417_0.971_1_A

R07E5_14P00042

R07E5_14P00066

R07E5_14P00321

R07E5_2P00013

WBGene00004387

cea2.c.22071

Participates

as a component of

Magoh-Y14 complex [cytosol] (Caenorhabditis elegans)

Other forms of this molecule

rnp-4 [nucleoplasm]

Inferred From

RBM8A [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_497891.1

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