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pvf-1 [extracellular region]
Stable Identifier
R-CEL-184199
Type
Protein [EntityWithAccessionedSequence]
Species
Caenorhabditis elegans
Compartment
extracellular region
Synonyms
PDGFA-1, Q9N413
Locations in the PathwayBrowser
Expand all
Extracellular matrix organization (Caenorhabditis elegans)
Non-integrin membrane-ECM interactions (Caenorhabditis elegans)
HSPG2 binds FGF2(10-155), Fibronectn matrix, Transthyretin tetramer, PDGFA homodimer, PDGFB homodimer (Caenorhabditis elegans)
FGF2(10-155), Fibronectn matrix, Transthyretin tetramer, PDGFA homodimer, PDGFB homodimer [extracellular region] (Caenorhabditis elegans)
active PDGF-AA dimer [extracellular region] (Caenorhabditis elegans)
pvf-1 [extracellular region] (Caenorhabditis elegans)
HSPG2:FGF2(10-155), Fibronectn matrix, Transthyretin tetramer, PDGFA homodimer, PDGFB homodimer [extracellular region] (Caenorhabditis elegans)
FGF2(10-155), Fibronectn matrix, Transthyretin tetramer, PDGFA homodimer, PDGFB homodimer [extracellular region] (Caenorhabditis elegans)
active PDGF-AA dimer [extracellular region] (Caenorhabditis elegans)
pvf-1 [extracellular region] (Caenorhabditis elegans)
Hemostasis (Caenorhabditis elegans)
Platelet activation, signaling and aggregation (Caenorhabditis elegans)
Response to elevated platelet cytosolic Ca2+ (Caenorhabditis elegans)
Platelet degranulation (Caenorhabditis elegans)
Exocytosis of platelet alpha granule contents (Caenorhabditis elegans)
Platelet alpha granule contents [extracellular region] (Caenorhabditis elegans)
PDGF dimer [extracellular region] (Caenorhabditis elegans)
PDGF AB heterodimer [extracellular region] (Caenorhabditis elegans)
pvf-1 [extracellular region] (Caenorhabditis elegans)
active PDGF-AA dimer [extracellular region] (Caenorhabditis elegans)
pvf-1 [extracellular region] (Caenorhabditis elegans)
Signal Transduction (Caenorhabditis elegans)
Intracellular signaling by second messengers (Caenorhabditis elegans)
PIP3 activates AKT signaling (Caenorhabditis elegans)
Negative regulation of the PI3K/AKT network (Caenorhabditis elegans)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Caenorhabditis elegans)
PI3K phosphorylates PIP2 to PIP3 (Caenorhabditis elegans)
Activator:PI3K [plasma membrane] (Caenorhabditis elegans)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Caenorhabditis elegans)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Caenorhabditis elegans)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Caenorhabditis elegans)
active PDGF-AA dimer [extracellular region] (Caenorhabditis elegans)
pvf-1 [extracellular region] (Caenorhabditis elegans)
PI3K phosphorylates PIP2 to PIP3 (Caenorhabditis elegans)
Activator:PI3K [plasma membrane] (Caenorhabditis elegans)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Caenorhabditis elegans)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Caenorhabditis elegans)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Caenorhabditis elegans)
active PDGF-AA dimer [extracellular region] (Caenorhabditis elegans)
pvf-1 [extracellular region] (Caenorhabditis elegans)
MAPK family signaling cascades (Caenorhabditis elegans)
MAPK1/MAPK3 signaling (Caenorhabditis elegans)
RAF/MAP kinase cascade (Caenorhabditis elegans)
RAS GEFs promote RAS nucleotide exchange (Caenorhabditis elegans)
RAS GEFs [plasma membrane] (Caenorhabditis elegans)
PDGF:Phospho-PDGF receptor dimer:Grb2:Sos1 [plasma membrane] (Caenorhabditis elegans)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Caenorhabditis elegans)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Caenorhabditis elegans)
active PDGF-AA dimer [extracellular region] (Caenorhabditis elegans)
pvf-1 [extracellular region] (Caenorhabditis elegans)
Signaling by Receptor Tyrosine Kinases (Caenorhabditis elegans)
Signaling by PDGF (Caenorhabditis elegans)
Autophosphorylation of PDGF alpha receptors (Caenorhabditis elegans)
PDGF alpha receptor: PDGF dimers [plasma membrane] (Caenorhabditis elegans)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Caenorhabditis elegans)
active PDGF-AA dimer [extracellular region] (Caenorhabditis elegans)
pvf-1 [extracellular region] (Caenorhabditis elegans)
PDGFR:type I PDGFR-binding TKIs [plasma membrane] (Caenorhabditis elegans)
PDGF alpha receptor: PDGF dimers [plasma membrane] (Caenorhabditis elegans)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Caenorhabditis elegans)
active PDGF-AA dimer [extracellular region] (Caenorhabditis elegans)
pvf-1 [extracellular region] (Caenorhabditis elegans)
Phospho PDGF alpha receptor:PDGF dimers [plasma membrane] (Caenorhabditis elegans)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Caenorhabditis elegans)
active PDGF-AA dimer [extracellular region] (Caenorhabditis elegans)
pvf-1 [extracellular region] (Caenorhabditis elegans)
Downstream signal transduction (Caenorhabditis elegans)
Activation of Src (Caenorhabditis elegans)
PDGF:Phospho-PDGF receptor dimer:MyrG-SRC [plasma membrane] (Caenorhabditis elegans)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Caenorhabditis elegans)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Caenorhabditis elegans)
active PDGF-AA dimer [extracellular region] (Caenorhabditis elegans)
pvf-1 [extracellular region] (Caenorhabditis elegans)
PDGF:Phospho-PDGF receptor dimer:MyrG-p-Y419-SRC [plasma membrane] (Caenorhabditis elegans)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Caenorhabditis elegans)
active PDGF-AA dimer [extracellular region] (Caenorhabditis elegans)
pvf-1 [extracellular region] (Caenorhabditis elegans)
Crk binds to the active PDGF receptor (Caenorhabditis elegans)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Caenorhabditis elegans)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Caenorhabditis elegans)
active PDGF-AA dimer [extracellular region] (Caenorhabditis elegans)
pvf-1 [extracellular region] (Caenorhabditis elegans)
PDGF:Phospho-PDGF receptor dimer:Crk [plasma membrane] (Caenorhabditis elegans)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Caenorhabditis elegans)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Caenorhabditis elegans)
active PDGF-AA dimer [extracellular region] (Caenorhabditis elegans)
pvf-1 [extracellular region] (Caenorhabditis elegans)
GRB2:SOS1 complex binds to the active receptor (Caenorhabditis elegans)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Caenorhabditis elegans)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Caenorhabditis elegans)
active PDGF-AA dimer [extracellular region] (Caenorhabditis elegans)
pvf-1 [extracellular region] (Caenorhabditis elegans)
PDGF:Phospho-PDGF receptor dimer:Grb2:Sos1 [plasma membrane] (Caenorhabditis elegans)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Caenorhabditis elegans)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Caenorhabditis elegans)
active PDGF-AA dimer [extracellular region] (Caenorhabditis elegans)
pvf-1 [extracellular region] (Caenorhabditis elegans)
Nck binds to the active PDGF receptor (Caenorhabditis elegans)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Caenorhabditis elegans)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Caenorhabditis elegans)
active PDGF-AA dimer [extracellular region] (Caenorhabditis elegans)
pvf-1 [extracellular region] (Caenorhabditis elegans)
PDGF:Phospho-PDGFR receptor dimer:Nck [plasma membrane] (Caenorhabditis elegans)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Caenorhabditis elegans)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Caenorhabditis elegans)
active PDGF-AA dimer [extracellular region] (Caenorhabditis elegans)
pvf-1 [extracellular region] (Caenorhabditis elegans)
PI3-kinase binds to the active receptor (Caenorhabditis elegans)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Caenorhabditis elegans)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Caenorhabditis elegans)
active PDGF-AA dimer [extracellular region] (Caenorhabditis elegans)
pvf-1 [extracellular region] (Caenorhabditis elegans)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Caenorhabditis elegans)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Caenorhabditis elegans)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Caenorhabditis elegans)
active PDGF-AA dimer [extracellular region] (Caenorhabditis elegans)
pvf-1 [extracellular region] (Caenorhabditis elegans)
PI3K catalyses the phosphorylation of PIP2 to PIP3 (Caenorhabditis elegans)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Caenorhabditis elegans)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Caenorhabditis elegans)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Caenorhabditis elegans)
active PDGF-AA dimer [extracellular region] (Caenorhabditis elegans)
pvf-1 [extracellular region] (Caenorhabditis elegans)
Phosphorylation of PLCgamma by PDGFR (Caenorhabditis elegans)
PDGF:Phospho-PDGF receptor dimer:PLC-gamma [plasma membrane] (Caenorhabditis elegans)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Caenorhabditis elegans)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Caenorhabditis elegans)
active PDGF-AA dimer [extracellular region] (Caenorhabditis elegans)
pvf-1 [extracellular region] (Caenorhabditis elegans)
PDGF:p-PDGFR dimer:p-PLCgamma [plasma membrane] (Caenorhabditis elegans)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Caenorhabditis elegans)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Caenorhabditis elegans)
active PDGF-AA dimer [extracellular region] (Caenorhabditis elegans)
pvf-1 [extracellular region] (Caenorhabditis elegans)
SH2 domain of Src binds to the active receptor (Caenorhabditis elegans)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Caenorhabditis elegans)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Caenorhabditis elegans)
active PDGF-AA dimer [extracellular region] (Caenorhabditis elegans)
pvf-1 [extracellular region] (Caenorhabditis elegans)
PDGF:Phospho-PDGF receptor dimer:MyrG-SRC [plasma membrane] (Caenorhabditis elegans)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Caenorhabditis elegans)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Caenorhabditis elegans)
active PDGF-AA dimer [extracellular region] (Caenorhabditis elegans)
pvf-1 [extracellular region] (Caenorhabditis elegans)
SOS-mediated nucleotide exchange on RAS (PDGF receptor:GRB2:SOS) (Caenorhabditis elegans)
PDGF:Phospho-PDGF receptor dimer:Grb2:Sos1 [plasma membrane] (Caenorhabditis elegans)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Caenorhabditis elegans)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Caenorhabditis elegans)
active PDGF-AA dimer [extracellular region] (Caenorhabditis elegans)
pvf-1 [extracellular region] (Caenorhabditis elegans)
STAT binds to the active receptor (Caenorhabditis elegans)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Caenorhabditis elegans)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Caenorhabditis elegans)
active PDGF-AA dimer [extracellular region] (Caenorhabditis elegans)
pvf-1 [extracellular region] (Caenorhabditis elegans)
PDGF:phospho-PDGF receptor dimer:STAT [plasma membrane] (Caenorhabditis elegans)
PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Caenorhabditis elegans)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Caenorhabditis elegans)
active PDGF-AA dimer [extracellular region] (Caenorhabditis elegans)
pvf-1 [extracellular region] (Caenorhabditis elegans)
PDGF dimer binds two receptors simultaneously (Caenorhabditis elegans)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Caenorhabditis elegans)
active PDGF-AA dimer [extracellular region] (Caenorhabditis elegans)
pvf-1 [extracellular region] (Caenorhabditis elegans)
PDGF:PDGF receptor dimer [plasma membrane] (Caenorhabditis elegans)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Caenorhabditis elegans)
active PDGF-AA dimer [extracellular region] (Caenorhabditis elegans)
pvf-1 [extracellular region] (Caenorhabditis elegans)
PDGF-AA clevage by Furin (Caenorhabditis elegans)
active PDGF-AA dimer [extracellular region] (Caenorhabditis elegans)
pvf-1 [extracellular region] (Caenorhabditis elegans)
PDGFRs bind type I TKI (Caenorhabditis elegans)
PDGF alpha receptor: PDGF dimers [plasma membrane] (Caenorhabditis elegans)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Caenorhabditis elegans)
active PDGF-AA dimer [extracellular region] (Caenorhabditis elegans)
pvf-1 [extracellular region] (Caenorhabditis elegans)
PDGFR:type I PDGFR-binding TKIs [plasma membrane] (Caenorhabditis elegans)
PDGF alpha receptor: PDGF dimers [plasma membrane] (Caenorhabditis elegans)
Active PDGF dimers (AA, AB, BB) [extracellular region] (Caenorhabditis elegans)
active PDGF-AA dimer [extracellular region] (Caenorhabditis elegans)
pvf-1 [extracellular region] (Caenorhabditis elegans)
External Reference Information
External Reference
UniProt:Q9N413
Gene Names
pvf-1
Reference Genes
BioGPS Gene:175327 pvf-1
CTD Gene:175327 pvf-1
ENSEMBL:WBGene00004249
KEGG Gene (Caenorhabditis elegans):CELE_Y39A3CL.6 pvf-1
Monarch:175327 pvf-1
NCBI Gene:175327 pvf-1
UCSC:Q9N413 pvf-1
Wormbase:WBGene00004249
Reference Transcript
RefSeq:NM_065060.3 pvf-1
Other Identifiers
175327
18529273
187026_s_at
A_12_P105213
CE21657
CE_WBGene00004249_A
CGZ0044799
GO:0008083
GO:0016020
GO:0048018
GO:0098772
WBGene00004249
Y39A3CL.6
Y39A3CL.6_327-386_0.917_6_C
Y39A3CL.6_553-612_0.930_1_A
Y39A3CL.6_641-700_0.925_2_B
Y39A3CL_6P00093
Y39A3CL_6P00389
Y39A3CL_6P00557
cea2.p.76609
Participates
as a component of
PDGF AB heterodimer [extracellular region] (Caenorhabditis elegans)
active PDGF-AA dimer [extracellular region] (Caenorhabditis elegans)
Other forms of this molecule
pvf-1 [platelet alpha granule lumen]
pvf-1 [platelet alpha granule lumen]
pvf-1 [platelet alpha granule lumen]
pvf-1 [extracellular region]
pvf-1 [extracellular region]
pvf-1 [extracellular region]
pvf-1 [extracellular region]
pvf-1 [extracellular region]
pvf-1 [extracellular region]
pvf-1 [Golgi lumen]
pvf-1 [Golgi lumen]
pvf-1 [Golgi membrane]
pvf-1 [Golgi membrane]
pvf-1 [Golgi membrane]
pvf-1 [endoplasmic reticulum lumen]
pvf-1 [endoplasmic reticulum lumen]
pvf-1 [endoplasmic reticulum lumen]
pvf-1 [endoplasmic reticulum lumen]
pvf-1 [endoplasmic reticulum lumen]
pvf-1 [Golgi lumen]
pvf-1 [Golgi membrane]
pvf-1 [Golgi membrane]
pvf-1 [extracellular region]
pvf-1 [extracellular region]
pvf-1 [extracellular region]
Inferred From
PDGFA [extracellular region]
(Homo sapiens)
Active platelet-derived growth factor A chain isoforms [extracellular region]
(Homo sapiens)
PDGFA-1 [extracellular region]
(Homo sapiens)
Cross References
RefSeq
NP_497461.1
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