Reactome | let-756 [extracellular region]

let-756 [extracellular region]

Stable Identifier

R-CEL-189898

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

extracellular region

Synonyms

FGF2(10-155), Q11184

Locations in the PathwayBrowser

Expand all

Signal Transduction (Caenorhabditis elegans)

- Signaling by Receptor Tyrosine Kinases (Caenorhabditis elegans)
  - Signaling by FGFR (Caenorhabditis elegans)
    - Signaling by FGFR1 (Caenorhabditis elegans)
      - FGFRL1 modulation of FGFR1 signaling (Caenorhabditis elegans)
        
        FGFRL1 dimer binds FGFs (Caenorhabditis elegans)
        
        FGFRL1-binding FGFs [extracellular region] (Caenorhabditis elegans)
        
        let-756 [extracellular region] (Caenorhabditis elegans)
        
        FGFRL1-binding FGFs:FGFRL1 dimer [plasma membrane] (Caenorhabditis elegans)
        
        FGFRL1-binding FGFs [extracellular region] (Caenorhabditis elegans)
        
        let-756 [extracellular region] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:Q11184

Gene Names

let-756

Reference Genes

BioGPS Gene:175909 let-756

CTD Gene:175909 let-756

ENSEMBL:WBGene00002881

KEGG:cel:CELE_C05D11.4 let-756

Monarch:175909 let-756

NCBI Entrez Gene:175909 let-756

UCSC:Q11184 let-756

Wormbase:WBGene00002881

Wormbase:WBGene00002881 let-756

Reference Transcript

RefSeq:NM_066002.7 let-756

Other Identifiers

175909

GO:0002119

GO:0005104

GO:0005515

GO:0005615

GO:0005634

GO:0005654

GO:0005730

GO:0005737

GO:0008083

GO:0008284

GO:0008543

GO:0016020

GO:0016607

GO:0019901

GO:0022008

GO:0030154

GO:0030334

GO:0031345

GO:0043410

GO:0048018

GO:0048841

GO:0048856

GO:0061629

GO:0098772

Participates

as an input of

Syndecans 1, 2, 4, (3) bind FGF2 (Caenorhabditis elegans)

as a component of

SDC1,2,4,(3):FGF2 [plasma membrane] (Caenorhabditis elegans)

as a member of

as a candidate of

FGFRL1-binding FGFs [extracellular region] (Caenorhabditis elegans)

Other forms of this molecule

let-756 [extracellular region]

Inferred From

FGF2(10-155) [extracellular region] (Homo sapiens)

Cross References

RefSeq

NP_498403.1

ENSEMBL

WBGene00002881, C05D11.4.1, C05D11.4.1

PRO

Q11184

Interactors (11)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P28548	5	kin-10 [ficolin-1-rich granule lumen] (R-CEL-6801290) kin-10 [extracellular region] (R-CEL-6806508) kin-10 [secretory granule lumen] (R-CEL-6801319) kin-10 [nucleoplasm] (R-CEL-6805067) kin-10 [cytosol] (R-CEL-201693)	0.543	3
UniProt:P41932	5	par-5 [nucleoplasm] (R-CEL-450469) par-5 [cytosol] (R-CEL-1445105) par-5 [cytosol] (R-CEL-1445116) par-5 [cytosol] (R-CEL-48888) par-5 [cytosol] (R-CEL-380312)	0.543	3
UniProt:P47991	1	rpl-6 [cytosol] (R-CEL-72484)	0.543	3
UniProt:P18334	4	CSNK2A1 [nucleoplasm] (R-CEL-6805057) CSNK2A2 [nucleoplasm] (R-CEL-6805065) CSNK2A2 [cytosol] (R-CEL-201721) CSNK2A1 [cytosol] (R-CEL-201713)	0.543	3
UniProt:Q22054	2	rps-16 [nucleoplasm] (R-CEL-6791196) rps-16 [cytosol] (R-CEL-72337)	0.543	4
UniProt:Q20655	6	ftt-2 [nucleoplasm] (R-CEL-450469-2) ftt-2 [cytosol] (R-CEL-1445105-2) ftt-2 [cytosol] (R-CEL-1445107) ftt-2 [cytosol] (R-CEL-1445116-2) ftt-2 [cytosol] (R-CEL-48888-2) ftt-2 [cytosol] (R-CEL-380312-2)	0.543	3
UniProt:Q21556 Q21556			0.543	4
UniProt:P31946 YWHAB	1	YWHAB [cytosol] (R-HSA-48888)	0.508	2
UniProt:Q09958	1	EBNA1BP2 [nucleoplasm] (R-CEL-8869325)	0.508	2
UniProt:Q18688	11	HSP90AA1 [ficolin-1-rich granule lumen] (R-CEL-6801470) HSP90AB1 [ficolin-1-rich granule lumen] (R-CEL-6801491) HSP90AB1 [extracellular region] (R-CEL-6806463) HSP90AB1 [secretory granule lumen] (R-CEL-6801477) HSP90AA1 [secretory granule lumen] (R-CEL-6801515) HSP90AA1 [extracellular region] (R-CEL-3221946) HSP90AA1 [plasma membrane] (R-CEL-534996) HSP90AB1 [cytosol] (R-CEL-419617) HSP90AA1 [nucleoplasm] (R-CEL-5082401) HSP90AB1 [nucleoplasm] (R-CEL-5082399) HSP90AA1 [cytosol] (R-CEL-192864)	0.508	3
UniProt:G5EDD8 G5EDD8			0.508	3

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