Reactome | cyk-4 [cytosol]

cyk-4 [cytosol]

Stable Identifier

R-CEL-195122

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

cytosol

Synonyms

RACGAP1, Q9XUS9

Locations in the PathwayBrowser

Expand all

Vesicle-mediated transport (Caenorhabditis elegans)

- Membrane Trafficking (Caenorhabditis elegans)
  - Intra-Golgi and retrograde Golgi-to-ER traffic (Caenorhabditis elegans)
    - Golgi-to-ER retrograde transport (Caenorhabditis elegans)
      - COPI-dependent Golgi-to-ER retrograde traffic (Caenorhabditis elegans)
        
        Retrograde COPI vesicles bind kinesin and microtubules (Caenorhabditis elegans)
        
        Kinesins:microtubule [cytosol] (Caenorhabditis elegans)
        
        Kinesins [cytosol] (Caenorhabditis elegans)
        
        Centralspindlin [cytosol] (Caenorhabditis elegans)
        
        cyk-4 [cytosol] (Caenorhabditis elegans)
        
        RAB1:GTP:coatomer:p24 dimers:SEC22B:kinesins:microtubules [transport vesicle] (Caenorhabditis elegans)
        
        Kinesins:microtubule [cytosol] (Caenorhabditis elegans)
        
        Kinesins [cytosol] (Caenorhabditis elegans)
        
        Centralspindlin [cytosol] (Caenorhabditis elegans)
        
        cyk-4 [cytosol] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:Q9XUS9

Gene Names

cyk-4

Reference Genes

BioGPS Gene:176815 cyk-4

CTD Gene:176815 cyk-4

ENSEMBL:WBGene00000875

KEGG:cel:CELE_K08E3.6 cyk-4

Monarch:176815 cyk-4

NCBI Gene:176815 cyk-4

UCSC:Q9XUS9 cyk-4

Wormbase:WBGene00000875

Wormbase:WBGene00000875 cyk-4

Reference Transcript

RefSeq:NM_067444.6 cyk-4

Other Identifiers

176815

18525738

194139_s_at

A_12_P103516

A_12_P175072

CE18872

CE_WBGene00000875_A

CGZ0028539

CGZ0028540

GO:0000070

GO:0000281

GO:0000910

GO:0005096

GO:0005515

GO:0005634

GO:0005819

GO:0005886

GO:0007010

GO:0007059

GO:0007165

GO:0007266

GO:0022414

GO:0030496

GO:0032154

GO:0040038

GO:0043226

GO:0046872

GO:0051233

GO:0051255

GO:0051256

GO:0061024

GO:0097149

GO:0098772

GO:1903562

GO:1990023

GO:1990386

K08E3.6

K08E3.6_1284-1343_0.833_46_C

K08E3.6_1479-1538_0.881_18_B

K08E3.6_1658-1717_0.930_3_A

K08E3_6P01019

K08E3_6P01555

K08E3_6P01951

WBGene00000875

cea2.p.68513

Participates

as a candidate of

as a member of

RAC3 GAPs [cytosol] (Caenorhabditis elegans)

as an input of

Kinesin-6 and RACGAP1 form the heterotetrameric complex centralspindlin (Caenorhabditis elegans)

as a component of

Centralspindlin [cytosol] (Caenorhabditis elegans)

Inferred From

RACGAP1 [cytosol] (Homo sapiens)

Cross References

ENSEMBL

WBGene00000875, K08E3.6.1, K08E3.6.1

PDB

7EQC

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:G5EG83 G5EG83			0.622	5
UniProt:Q8MQ03	3	KIF23 [cytosol] (R-CEL-1015863) phospho-p-S911,S912-KIF23 [nucleoplasm] (R-CEL-156695) KIF23 [nucleoplasm] (R-CEL-156709)	0.544	6