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arx-6 [cytosol]
Stable Identifier
R-CEL-200813
Type
Protein [EntityWithAccessionedSequence]
Species
Caenorhabditis elegans
Compartment
cytosol
Synonyms
ARPC4, P58798
Locations in the PathwayBrowser
Expand all
Developmental Biology (Caenorhabditis elegans)
Nervous system development (Caenorhabditis elegans)
Axon guidance (Caenorhabditis elegans)
EPH-Ephrin signaling (Caenorhabditis elegans)
EPHB-mediated forward signaling (Caenorhabditis elegans)
N-WASP binds ARP2/3 and G-actin (Caenorhabditis elegans)
ARP2/3 complex (ATP bound) [cytosol] (Caenorhabditis elegans)
arx-6 [cytosol] (Caenorhabditis elegans)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2:ARP2/3;G-actin [plasma membrane] (Caenorhabditis elegans)
ARP2/3 complex (ATP bound) [cytosol] (Caenorhabditis elegans)
arx-6 [cytosol] (Caenorhabditis elegans)
Immune System (Caenorhabditis elegans)
Innate Immune System (Caenorhabditis elegans)
Fcgamma receptor (FCGR) dependent phagocytosis (Caenorhabditis elegans)
Regulation of actin dynamics for phagocytic cup formation (Caenorhabditis elegans)
(WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Caenorhabditis elegans)
Mother filament:branching complex [cytosol] (Caenorhabditis elegans)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Caenorhabditis elegans)
ARP2/3 complex (ATP bound) [cytosol] (Caenorhabditis elegans)
arx-6 [cytosol] (Caenorhabditis elegans)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Caenorhabditis elegans)
ARP2/3 complex (ATP bound) [cytosol] (Caenorhabditis elegans)
arx-6 [cytosol] (Caenorhabditis elegans)
Branching and elongation of mother and daughter filaments (Caenorhabditis elegans)
Mother filament:ARP2/3:actin:ADP [cytosol] (Caenorhabditis elegans)
ARP2/3 complex (ATP bound) [cytosol] (Caenorhabditis elegans)
arx-6 [cytosol] (Caenorhabditis elegans)
Mother filament:branching complex:daughter filament [cytosol] (Caenorhabditis elegans)
ARP2/3 complex (ATP bound) [cytosol] (Caenorhabditis elegans)
arx-6 [cytosol] (Caenorhabditis elegans)
Detachment of WASP/WAVE (Caenorhabditis elegans)
Mother filament:ARP2/3:actin:ADP [cytosol] (Caenorhabditis elegans)
ARP2/3 complex (ATP bound) [cytosol] (Caenorhabditis elegans)
arx-6 [cytosol] (Caenorhabditis elegans)
Mother filament:branching complex [cytosol] (Caenorhabditis elegans)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Caenorhabditis elegans)
ARP2/3 complex (ATP bound) [cytosol] (Caenorhabditis elegans)
arx-6 [cytosol] (Caenorhabditis elegans)
Signal Transduction (Caenorhabditis elegans)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Caenorhabditis elegans)
Signaling by Rho GTPases (Caenorhabditis elegans)
RHO GTPase Effectors (Caenorhabditis elegans)
RHO GTPases Activate WASPs and WAVEs (Caenorhabditis elegans)
(WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Caenorhabditis elegans)
Mother filament:branching complex [cytosol] (Caenorhabditis elegans)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Caenorhabditis elegans)
ARP2/3 complex (ATP bound) [cytosol] (Caenorhabditis elegans)
arx-6 [cytosol] (Caenorhabditis elegans)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Caenorhabditis elegans)
ARP2/3 complex (ATP bound) [cytosol] (Caenorhabditis elegans)
arx-6 [cytosol] (Caenorhabditis elegans)
Branching and elongation of mother and daughter filaments (Caenorhabditis elegans)
Mother filament:ARP2/3:actin:ADP [cytosol] (Caenorhabditis elegans)
ARP2/3 complex (ATP bound) [cytosol] (Caenorhabditis elegans)
arx-6 [cytosol] (Caenorhabditis elegans)
Mother filament:branching complex:daughter filament [cytosol] (Caenorhabditis elegans)
ARP2/3 complex (ATP bound) [cytosol] (Caenorhabditis elegans)
arx-6 [cytosol] (Caenorhabditis elegans)
Detachment of WASP/WAVE (Caenorhabditis elegans)
Mother filament:ARP2/3:actin:ADP [cytosol] (Caenorhabditis elegans)
ARP2/3 complex (ATP bound) [cytosol] (Caenorhabditis elegans)
arx-6 [cytosol] (Caenorhabditis elegans)
Mother filament:branching complex [cytosol] (Caenorhabditis elegans)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Caenorhabditis elegans)
ARP2/3 complex (ATP bound) [cytosol] (Caenorhabditis elegans)
arx-6 [cytosol] (Caenorhabditis elegans)
Vesicle-mediated transport (Caenorhabditis elegans)
Membrane Trafficking (Caenorhabditis elegans)
Clathrin-mediated endocytosis (Caenorhabditis elegans)
Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle (Caenorhabditis elegans)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
ARP2/3 complex [cytosol] (Caenorhabditis elegans)
arx-6 [cytosol] (Caenorhabditis elegans)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
ARP2/3 complex [cytosol] (Caenorhabditis elegans)
arx-6 [cytosol] (Caenorhabditis elegans)
BAR domain proteins recruit dynamin (Caenorhabditis elegans)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Caenorhabditis elegans)
ARP2/3 complex [cytosol] (Caenorhabditis elegans)
arx-6 [cytosol] (Caenorhabditis elegans)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Caenorhabditis elegans)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Caenorhabditis elegans)
ARP2/3 complex [cytosol] (Caenorhabditis elegans)
arx-6 [cytosol] (Caenorhabditis elegans)
Clathrin recruits auxilins to the clathrin-coated vesicle (Caenorhabditis elegans)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
ARP2/3 complex [cytosol] (Caenorhabditis elegans)
arx-6 [cytosol] (Caenorhabditis elegans)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
ARP2/3 complex [cytosol] (Caenorhabditis elegans)
arx-6 [cytosol] (Caenorhabditis elegans)
Dynamin-mediated GTP hydrolysis promotes vesicle scission (Caenorhabditis elegans)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
ARP2/3 complex [cytosol] (Caenorhabditis elegans)
arx-6 [cytosol] (Caenorhabditis elegans)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Caenorhabditis elegans)
ARP2/3 complex [cytosol] (Caenorhabditis elegans)
arx-6 [cytosol] (Caenorhabditis elegans)
Endophilins recruit synaptojanins to the clathrin-coated pit (Caenorhabditis elegans)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Caenorhabditis elegans)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Caenorhabditis elegans)
ARP2/3 complex [cytosol] (Caenorhabditis elegans)
arx-6 [cytosol] (Caenorhabditis elegans)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Caenorhabditis elegans)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Caenorhabditis elegans)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Caenorhabditis elegans)
ARP2/3 complex [cytosol] (Caenorhabditis elegans)
arx-6 [cytosol] (Caenorhabditis elegans)
HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Caenorhabditis elegans)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
ARP2/3 complex [cytosol] (Caenorhabditis elegans)
arx-6 [cytosol] (Caenorhabditis elegans)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
ARP2/3 complex [cytosol] (Caenorhabditis elegans)
arx-6 [cytosol] (Caenorhabditis elegans)
RAB5 and GAPVD1 bind AP-2 (Caenorhabditis elegans)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
ARP2/3 complex [cytosol] (Caenorhabditis elegans)
arx-6 [cytosol] (Caenorhabditis elegans)
SYNJ hydrolyze PI(4,5)P2 to PI(4)P (Caenorhabditis elegans)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Caenorhabditis elegans)
ARP2/3 complex [cytosol] (Caenorhabditis elegans)
arx-6 [cytosol] (Caenorhabditis elegans)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Caenorhabditis elegans)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Caenorhabditis elegans)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Caenorhabditis elegans)
ARP2/3 complex [cytosol] (Caenorhabditis elegans)
arx-6 [cytosol] (Caenorhabditis elegans)
External Reference Information
External Reference
UniProt:P58798
Gene Names
arx-6
Reference Genes
BioGPS Gene:175650 arx-6
ENSEMBL:WBGene00000204
Monarch:175650 arx-6
NCBI Gene:175650 arx-6
UCSC:P58798 arx-6
Wormbase:WBGene00000204
Reference Transcript
RefSeq:NM_065619.4 arx-6
Other Identifiers
175650
18509709
A_12_P115620
C35D10.16
C35D10.16_160-219_0.942_3_B
C35D10.16_228-287_0.948_2_A
C35D10.16_52-111_0.896_22_C
C35D10_16P00001
C35D10_16P00306
C35D10_16P00429
CE28899
CE_WBGene00000204_A
CE_WBGene00000204_B
CGZ0007711
GO:0005856
GO:0005885
GO:0007010
GO:0015629
GO:0030041
GO:0034314
GO:0043226
GO:0065003
WBGene00000204
cea2.p.59131
Participates
as a component of
ARP2/3 complex [cytosol] (Caenorhabditis elegans)
ARP2/3 complex (ATP bound) [cytosol] (Caenorhabditis elegans)
Inferred From
ARPC4 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_498020.1
PRO
P58798
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