Reactome | pop-1 [nucleoplasm]

pop-1 [nucleoplasm]

Stable Identifier

R-CEL-201923

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

nucleoplasm

Synonyms

TCF7L2, Q10666

Locations in the PathwayBrowser

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Gene expression (Transcription) (Caenorhabditis elegans)

- RNA Polymerase II Transcription (Caenorhabditis elegans)
  - Generic Transcription Pathway (Caenorhabditis elegans)
    - Transcriptional regulation by RUNX3 (Caenorhabditis elegans)
      - RUNX3 regulates WNT signaling (Caenorhabditis elegans)
        
        RUNX3 binds CTNNB1:TCF7L2,(LEF1,TCF7L1,TCF7) (Caenorhabditis elegans)
        
        RUNX3:CTNNB1:TCF7L2,(LEF1,TCF7L1,TCF7) [nucleoplasm] (Caenorhabditis elegans)
        
        TCF/LEF:CTNNB1 [nucleoplasm] (Caenorhabditis elegans)
        
        pop-1 [nucleoplasm] (Caenorhabditis elegans)
        
        TCF/LEF:CTNNB1 [nucleoplasm] (Caenorhabditis elegans)
        
        pop-1 [nucleoplasm] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:Q10666

Gene Names

pop-1

Reference Genes

BioGPS Gene:171849 pop-1

ENSEMBL:WBGene00004077

KEGG Gene (Caenorhabditis elegans):CELE_W10C8.2 pop-1

Monarch:171849 pop-1

NCBI Gene:171849 pop-1

UCSC:Q10666 pop-1

Wormbase:WBGene00004077

Reference Transcript

RefSeq:NM_058652.3 pop-1

Other Identifiers

171849

18474424

188002_at

A_12_P117064

CE26031

CE_WBGene00004077_A

CE_WBGene00004077_C

CGZ0038982

GO:0007165

GO:0007267

GO:0008150

GO:0016055

W10C8.2

W10C8.2_1061-1120_0.931_2_C

W10C8.2_1186-1245_0.447_258_A

W10C8.2_1247-1306_0.937_1_B

W10C8_2P00232

W10C8_2P00930

W10C8_2P01104

WBGene00004077

cea2.c.06921

Participates

as a component of

as an input of

TCF7L2/TCF7L1 bind CTBP1 to repress WNT target genes (Caenorhabditis elegans)

Other forms of this molecule

phospho-pop-1 [nucleoplasm]

pop-1 [nucleoplasm]

Inferred From

TCF/LEF [nucleoplasm] (Homo sapiens)

TCF7L2/TCF7L1 [nucleoplasm] (Homo sapiens)

TCF7L2,(LEF1,TCF7L1,TCF7) [nucleoplasm] (Homo sapiens)

TCF7L2 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_491053.4

PRO

Q10666

PDB

3C2G

Interactors (24)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q18825	5	bar-1 [specific granule lumen] (R-CEL-6799534-3) bar-1 [cytosol] (R-CEL-201598-3) bar-1 [extracellular region] (R-CEL-6806309-3) bar-1 [ficolin-1-rich granule lumen] (R-CEL-6801028-3) bar-1 [plasma membrane] (R-CEL-437260-3)	0.785	6
UniProt:Q9XVI2 Q9XVI2			0.766	6
UniProt:O17670	8	eya-1 [nucleoplasm] (R-CEL-5683621) eya-1 [nucleoplasm] (R-CEL-5683625) eya-1 [nucleoplasm] (R-CEL-5683622) eya-1 [nucleoplasm] (R-CEL-5683958) phospho-eya-1 [nucleoplasm] (R-CEL-5683979) phospho-eya-1 [nucleoplasm] (R-CEL-5683981) phospho-eya-1 [nucleoplasm] (R-CEL-5683951) phospho-eya-1 [nucleoplasm] (R-CEL-5683954)	0.712	4
UniProt:Q18694 Q18694			0.621	3
UniProt:Q9XVD5	2	tbx-38 [nucleoplasm] (R-CEL-2032786-15) tbx-38 [nucleoplasm] (R-CEL-8953093-15)	0.621	3
UniProt:O18214 MAB3			0.621	3
UniProt:Q9NAE4 Q9NAE4			0.621	3
UniProt:Q10953	5	wrm-1 [specific granule lumen] (R-CEL-6799534-2) wrm-1 [cytosol] (R-CEL-201598-2) wrm-1 [extracellular region] (R-CEL-6806309-2) wrm-1 [ficolin-1-rich granule lumen] (R-CEL-6801028-2) wrm-1 [plasma membrane] (R-CEL-437260-2)	0.553	2
UniProt:P41932	6	par-5 [cytosol] (R-CEL-1445105) par-5 [nucleoplasm] (R-CEL-450469) par-5 [cytosol] (R-CEL-206099) par-5 [cytosol] (R-CEL-48888) par-5 [cytosol] (R-CEL-380312) par-5 [cytosol] (R-CEL-1445107)	0.524	2
UniProt:O02482	4	unc-37 [nucleoplasm] (R-CEL-3322363) unc-37 [nucleoplasm] (R-CEL-212377) unc-37 [nucleoplasm] (R-CEL-212354) unc-37 [nucleoplasm] (R-CEL-212327)	0.499	3
UniProt:O17695 HDA1			0.499	3
UniProt:Q94398 HM08			0.488	2
UniProt:Q7JNM3 Q7JNM3			0.488	2
UniProt:Q21648 Q21648			0.488	2
UniProt:H2KZ82 H2KZ82			0.488	2
UniProt:Q20257	2	tbx-11 [nucleoplasm] (R-CEL-2032786-3) tbx-11 [nucleoplasm] (R-CEL-8953093-3)	0.488	2
UniProt:Q20422 Q20422			0.488	2
UniProt:Q10666	6	phospho-pop-1 [nucleoplasm] (R-CEL-4411392) phospho-pop-1 [nucleoplasm] (R-CEL-4411389) pop-1 [nucleoplasm] (R-CEL-3299543) pop-1 [nucleoplasm] (R-CEL-5228649) pop-1 [nucleoplasm] (R-CEL-3214972) pop-1 [nucleoplasm] (R-CEL-201923)	0.488	2
UniProt:O17761	2	ech-8 [peroxisomal matrix] (R-CEL-400155) ech-8 [cytosol] (R-CEL-9033147)	0.488	2
UniProt:G5EE68 G5EE68			0.488	2
UniProt:O62203	2	phm-2 [nucleoplasm] (R-CEL-4085379) phm-2 [nucleoplasm] (R-CEL-4085343)	0.488	2
UniProt:Q9U1R1	1	ceh-51 [nucleoplasm] (R-CEL-452586-3)	0.488	2
UniProt:Q19503	1	ceh-40 [nucleoplasm] (R-CEL-453045-2)	0.488	2
UniProt:Q9NAH2	2	tbx-34 [nucleoplasm] (R-CEL-2032786-12) tbx-34 [nucleoplasm] (R-CEL-8953093-12)	0.488	2

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