Reactome | alg-1 [cytosol]

alg-1 [cytosol]

Stable Identifier

R-CEL-210612-4

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

cytosol

Synonyms

EIF2C4, G5EES3

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Caenorhabditis elegans)

- Gene Silencing by RNA (Caenorhabditis elegans)
  - MicroRNA (miRNA) biogenesis (Caenorhabditis elegans)
    - Duplex miRNA is loaded into Argonaute (Caenorhabditis elegans)
      - TARBP2,PRKRA RLC:duplex miRNA [cytosol] (Caenorhabditis elegans)
        
        PRKRA:DICER1:AGO1,2,3,4:duplex miRNA [cytosol] (Caenorhabditis elegans)
        
        PRKRA:DICER1:AGO1,2,3,4 [cytosol] (Caenorhabditis elegans)
        
        AGO1,2,3,4 [cytosol] (Caenorhabditis elegans)
        
        Homologues of EIF2C4 [cytosol] (Caenorhabditis elegans)
        
        alg-1 [cytosol] (Caenorhabditis elegans)
        
        RISC loading complex:duplex miRNA [cytosol] (Caenorhabditis elegans)
        
        RISC loading complex [cytosol] (Caenorhabditis elegans)
        
        AGO1,2,3,4 [cytosol] (Caenorhabditis elegans)
        
        Homologues of EIF2C4 [cytosol] (Caenorhabditis elegans)
        
        alg-1 [cytosol] (Caenorhabditis elegans)
      - TARBP2,PRKRA:DICER1:Pre-RISC (miRNA) [cytosol] (Caenorhabditis elegans)
        
        PRKRA:DICER1:Pre-RISC (miRNA) [cytosol] (Caenorhabditis elegans)
        
        pre-RISC (miRNA) [cytosol] (Caenorhabditis elegans)
        
        AGO4:duplex miRNA [cytosol] (Caenorhabditis elegans)
        
        Homologues of EIF2C4 [cytosol] (Caenorhabditis elegans)
        
        alg-1 [cytosol] (Caenorhabditis elegans)
        
        TARBP2:DICER1:Pre-RISC (miRNA) [cytosol] (Caenorhabditis elegans)
        
        pre-RISC (miRNA) [cytosol] (Caenorhabditis elegans)
        
        AGO4:duplex miRNA [cytosol] (Caenorhabditis elegans)
        
        Homologues of EIF2C4 [cytosol] (Caenorhabditis elegans)
        
        alg-1 [cytosol] (Caenorhabditis elegans)
    - Removal of miRNA passenger strand (Caenorhabditis elegans)
      - TARBP2,PRKRA:DICER1:Pre-RISC (miRNA) [cytosol] (Caenorhabditis elegans)
        
        PRKRA:DICER1:Pre-RISC (miRNA) [cytosol] (Caenorhabditis elegans)
        
        pre-RISC (miRNA) [cytosol] (Caenorhabditis elegans)
        
        AGO4:duplex miRNA [cytosol] (Caenorhabditis elegans)
        
        Homologues of EIF2C4 [cytosol] (Caenorhabditis elegans)
        
        alg-1 [cytosol] (Caenorhabditis elegans)
        
        TARBP2:DICER1:Pre-RISC (miRNA) [cytosol] (Caenorhabditis elegans)
        
        pre-RISC (miRNA) [cytosol] (Caenorhabditis elegans)
        
        AGO4:duplex miRNA [cytosol] (Caenorhabditis elegans)
        
        Homologues of EIF2C4 [cytosol] (Caenorhabditis elegans)
        
        alg-1 [cytosol] (Caenorhabditis elegans)
      - TARBP2,PRKRA:DICER1:RISC (miRNA) [cytosol] (Caenorhabditis elegans)
        
        PRKRA:DICER1:RISC (miRNA) [cytosol] (Caenorhabditis elegans)
        
        RISC (miRNA) [cytosol] (Caenorhabditis elegans)
        
        AGO4:miRNA [cytosol] (Caenorhabditis elegans)
        
        Homologues of EIF2C4 [cytosol] (Caenorhabditis elegans)
        
        alg-1 [cytosol] (Caenorhabditis elegans)
        
        TARBP2:DICER1:RISC (miRNA) [cytosol] (Caenorhabditis elegans)
        
        RISC (miRNA) [cytosol] (Caenorhabditis elegans)
        
        AGO4:miRNA [cytosol] (Caenorhabditis elegans)
        
        Homologues of EIF2C4 [cytosol] (Caenorhabditis elegans)
        
        alg-1 [cytosol] (Caenorhabditis elegans)
  - Small interfering RNA (siRNA) biogenesis (Caenorhabditis elegans)
    - Dicer cleaves double-stranded RNA to yield double-stranded siRNA (Caenorhabditis elegans)
      - TARBP2,PRKRA RLC [cytosol] (Caenorhabditis elegans)
        
        PRKRA:DICER1:AGO1,2,3,4 [cytosol] (Caenorhabditis elegans)
        
        AGO1,2,3,4 [cytosol] (Caenorhabditis elegans)
        
        Homologues of EIF2C4 [cytosol] (Caenorhabditis elegans)
        
        alg-1 [cytosol] (Caenorhabditis elegans)
        
        RISC loading complex [cytosol] (Caenorhabditis elegans)
        
        AGO1,2,3,4 [cytosol] (Caenorhabditis elegans)
        
        Homologues of EIF2C4 [cytosol] (Caenorhabditis elegans)
        
        alg-1 [cytosol] (Caenorhabditis elegans)
      - TARBP2,PRKRA RLC:duplex siRNA [cytosol] (Caenorhabditis elegans)
        
        PRKRA:DICER1:AGO1,2,3,4:duplex siRNA [cytosol] (Caenorhabditis elegans)
        
        PRKRA:DICER1:AGO1,2,3,4 [cytosol] (Caenorhabditis elegans)
        
        AGO1,2,3,4 [cytosol] (Caenorhabditis elegans)
        
        Homologues of EIF2C4 [cytosol] (Caenorhabditis elegans)
        
        alg-1 [cytosol] (Caenorhabditis elegans)
        
        RISC loading complex:duplex siRNA [cytosol] (Caenorhabditis elegans)
        
        RISC loading complex [cytosol] (Caenorhabditis elegans)
        
        AGO1,2,3,4 [cytosol] (Caenorhabditis elegans)
        
        Homologues of EIF2C4 [cytosol] (Caenorhabditis elegans)
        
        alg-1 [cytosol] (Caenorhabditis elegans)
    - Duplex siRNA is loaded into Argonaute (Caenorhabditis elegans)
      - TARBP2,PRKRA RLC:duplex siRNA [cytosol] (Caenorhabditis elegans)
        
        PRKRA:DICER1:AGO1,2,3,4:duplex siRNA [cytosol] (Caenorhabditis elegans)
        
        PRKRA:DICER1:AGO1,2,3,4 [cytosol] (Caenorhabditis elegans)
        
        AGO1,2,3,4 [cytosol] (Caenorhabditis elegans)
        
        Homologues of EIF2C4 [cytosol] (Caenorhabditis elegans)
        
        alg-1 [cytosol] (Caenorhabditis elegans)
        
        RISC loading complex:duplex siRNA [cytosol] (Caenorhabditis elegans)
        
        RISC loading complex [cytosol] (Caenorhabditis elegans)
        
        AGO1,2,3,4 [cytosol] (Caenorhabditis elegans)
        
        Homologues of EIF2C4 [cytosol] (Caenorhabditis elegans)
        
        alg-1 [cytosol] (Caenorhabditis elegans)
      - TARBP2,PRKRA:DICER1:Pre-RISC (siRNA) [cytosol] (Caenorhabditis elegans)
        
        PRKRA:DICER1:Pre-RISC (siRNA) [cytosol] (Caenorhabditis elegans)
        
        pre-RISC (siRNA) [cytosol] (Caenorhabditis elegans)
        
        AGO4:duplex siRNA [cytosol] (Caenorhabditis elegans)
        
        Homologues of EIF2C4 [cytosol] (Caenorhabditis elegans)
        
        alg-1 [cytosol] (Caenorhabditis elegans)
        
        TARBP2:DICER1:Pre-RISC (siRNA) [cytosol] (Caenorhabditis elegans)
        
        pre-RISC (siRNA) [cytosol] (Caenorhabditis elegans)
        
        AGO4:duplex siRNA [cytosol] (Caenorhabditis elegans)
        
        Homologues of EIF2C4 [cytosol] (Caenorhabditis elegans)
        
        alg-1 [cytosol] (Caenorhabditis elegans)
    - Removal of siRNA passenger strand (Caenorhabditis elegans)
      - TARBP2,PRKRA:DICER1:Pre-RISC (siRNA) [cytosol] (Caenorhabditis elegans)
        
        PRKRA:DICER1:Pre-RISC (siRNA) [cytosol] (Caenorhabditis elegans)
        
        pre-RISC (siRNA) [cytosol] (Caenorhabditis elegans)
        
        AGO4:duplex siRNA [cytosol] (Caenorhabditis elegans)
        
        Homologues of EIF2C4 [cytosol] (Caenorhabditis elegans)
        
        alg-1 [cytosol] (Caenorhabditis elegans)
        
        TARBP2:DICER1:Pre-RISC (siRNA) [cytosol] (Caenorhabditis elegans)
        
        pre-RISC (siRNA) [cytosol] (Caenorhabditis elegans)
        
        AGO4:duplex siRNA [cytosol] (Caenorhabditis elegans)
        
        Homologues of EIF2C4 [cytosol] (Caenorhabditis elegans)
        
        alg-1 [cytosol] (Caenorhabditis elegans)
      - TARBP2,PRKRA:DICER1:RISC (siRNA) [cytosol] (Caenorhabditis elegans)
        
        PRKRA:DICER1:RISC (siRNA) [cytosol] (Caenorhabditis elegans)
        
        RISC (siRNA) [cytosol] (Caenorhabditis elegans)
        
        AGO4:siRNA [cytosol] (Caenorhabditis elegans)
        
        Homologues of EIF2C4 [cytosol] (Caenorhabditis elegans)
        
        alg-1 [cytosol] (Caenorhabditis elegans)
        
        TARBP2:DICER1:RISC (siRNA) [cytosol] (Caenorhabditis elegans)
        
        RISC (siRNA) [cytosol] (Caenorhabditis elegans)
        
        AGO4:siRNA [cytosol] (Caenorhabditis elegans)
        
        Homologues of EIF2C4 [cytosol] (Caenorhabditis elegans)
        
        alg-1 [cytosol] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:G5EES3

Gene Names

alg-1

Reference Genes

ENSEMBL:WBGene00000105

Wormbase:WBGene00000105

Reference Transcript

RefSeq:NM_001270310.1 alg-1

Other Identifiers

174189_at

177915_at

181504

18610966

A_12_P112873

CE31525

CE_WBGene00000105_A

CE_WBGene00000105_B

F48F7.1

F48F7.1b_2599-2658_0.796_114_C

F48F7.1b_2682-2741_0.942_3_B

F48F7.1b_2844-2903_0.956_1_A

F48F7_1P01682

F48F7_1P02275

F48F7_1P02631

GO:0003676

GO:0005515

WBGene00000105

Participates

as a member of

Homologues of EIF2C4 [cytosol] (Caenorhabditis elegans)

Other forms of this molecule

alg-1 [nucleoplasm]

alg-1 [cytosol]

Inferred From

EIF2C4 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001257239.1

Cite Us!