Reactome | alg-3 [cytosol]

alg-3 [cytosol]

Stable Identifier

R-CEL-210616-2

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

cytosol

Synonyms

EIF2C1, G5ED77

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Caenorhabditis elegans)

- Gene Silencing by RNA (Caenorhabditis elegans)
  - MicroRNA (miRNA) biogenesis (Caenorhabditis elegans)
    - Duplex miRNA is loaded into Argonaute (Caenorhabditis elegans)
      - TARBP2,PRKRA RLC:duplex miRNA [cytosol] (Caenorhabditis elegans)
        
        PRKRA:DICER1:AGO1,2,3,4:duplex miRNA [cytosol] (Caenorhabditis elegans)
        
        PRKRA:DICER1:AGO1,2,3,4 [cytosol] (Caenorhabditis elegans)
        
        AGO1,2,3,4 [cytosol] (Caenorhabditis elegans)
        
        Homologues of EIF2C1 [cytosol] (Caenorhabditis elegans)
        
        alg-3 [cytosol] (Caenorhabditis elegans)
        
        RISC loading complex:duplex miRNA [cytosol] (Caenorhabditis elegans)
        
        RISC loading complex [cytosol] (Caenorhabditis elegans)
        
        AGO1,2,3,4 [cytosol] (Caenorhabditis elegans)
        
        Homologues of EIF2C1 [cytosol] (Caenorhabditis elegans)
        
        alg-3 [cytosol] (Caenorhabditis elegans)
      - TARBP2,PRKRA:DICER1:Pre-RISC (miRNA) [cytosol] (Caenorhabditis elegans)
        
        PRKRA:DICER1:Pre-RISC (miRNA) [cytosol] (Caenorhabditis elegans)
        
        pre-RISC (miRNA) [cytosol] (Caenorhabditis elegans)
        
        AGO1:duplex miRNA [cytosol] (Caenorhabditis elegans)
        
        Homologues of EIF2C1 [cytosol] (Caenorhabditis elegans)
        
        alg-3 [cytosol] (Caenorhabditis elegans)
        
        TARBP2:DICER1:Pre-RISC (miRNA) [cytosol] (Caenorhabditis elegans)
        
        pre-RISC (miRNA) [cytosol] (Caenorhabditis elegans)
        
        AGO1:duplex miRNA [cytosol] (Caenorhabditis elegans)
        
        Homologues of EIF2C1 [cytosol] (Caenorhabditis elegans)
        
        alg-3 [cytosol] (Caenorhabditis elegans)
    - Removal of miRNA passenger strand (Caenorhabditis elegans)
      - TARBP2,PRKRA:DICER1:Pre-RISC (miRNA) [cytosol] (Caenorhabditis elegans)
        
        PRKRA:DICER1:Pre-RISC (miRNA) [cytosol] (Caenorhabditis elegans)
        
        pre-RISC (miRNA) [cytosol] (Caenorhabditis elegans)
        
        AGO1:duplex miRNA [cytosol] (Caenorhabditis elegans)
        
        Homologues of EIF2C1 [cytosol] (Caenorhabditis elegans)
        
        alg-3 [cytosol] (Caenorhabditis elegans)
        
        TARBP2:DICER1:Pre-RISC (miRNA) [cytosol] (Caenorhabditis elegans)
        
        pre-RISC (miRNA) [cytosol] (Caenorhabditis elegans)
        
        AGO1:duplex miRNA [cytosol] (Caenorhabditis elegans)
        
        Homologues of EIF2C1 [cytosol] (Caenorhabditis elegans)
        
        alg-3 [cytosol] (Caenorhabditis elegans)
      - TARBP2,PRKRA:DICER1:RISC (miRNA) [cytosol] (Caenorhabditis elegans)
        
        PRKRA:DICER1:RISC (miRNA) [cytosol] (Caenorhabditis elegans)
        
        RISC (miRNA) [cytosol] (Caenorhabditis elegans)
        
        AGO1:miRNA [cytosol] (Caenorhabditis elegans)
        
        Homologues of EIF2C1 [cytosol] (Caenorhabditis elegans)
        
        alg-3 [cytosol] (Caenorhabditis elegans)
        
        TARBP2:DICER1:RISC (miRNA) [cytosol] (Caenorhabditis elegans)
        
        RISC (miRNA) [cytosol] (Caenorhabditis elegans)
        
        AGO1:miRNA [cytosol] (Caenorhabditis elegans)
        
        Homologues of EIF2C1 [cytosol] (Caenorhabditis elegans)
        
        alg-3 [cytosol] (Caenorhabditis elegans)
  - Small interfering RNA (siRNA) biogenesis (Caenorhabditis elegans)
    - Dicer cleaves double-stranded RNA to yield double-stranded siRNA (Caenorhabditis elegans)
      - TARBP2,PRKRA RLC [cytosol] (Caenorhabditis elegans)
        
        PRKRA:DICER1:AGO1,2,3,4 [cytosol] (Caenorhabditis elegans)
        
        AGO1,2,3,4 [cytosol] (Caenorhabditis elegans)
        
        Homologues of EIF2C1 [cytosol] (Caenorhabditis elegans)
        
        alg-3 [cytosol] (Caenorhabditis elegans)
        
        RISC loading complex [cytosol] (Caenorhabditis elegans)
        
        AGO1,2,3,4 [cytosol] (Caenorhabditis elegans)
        
        Homologues of EIF2C1 [cytosol] (Caenorhabditis elegans)
        
        alg-3 [cytosol] (Caenorhabditis elegans)
      - TARBP2,PRKRA RLC:duplex siRNA [cytosol] (Caenorhabditis elegans)
        
        PRKRA:DICER1:AGO1,2,3,4:duplex siRNA [cytosol] (Caenorhabditis elegans)
        
        PRKRA:DICER1:AGO1,2,3,4 [cytosol] (Caenorhabditis elegans)
        
        AGO1,2,3,4 [cytosol] (Caenorhabditis elegans)
        
        Homologues of EIF2C1 [cytosol] (Caenorhabditis elegans)
        
        alg-3 [cytosol] (Caenorhabditis elegans)
        
        RISC loading complex:duplex siRNA [cytosol] (Caenorhabditis elegans)
        
        RISC loading complex [cytosol] (Caenorhabditis elegans)
        
        AGO1,2,3,4 [cytosol] (Caenorhabditis elegans)
        
        Homologues of EIF2C1 [cytosol] (Caenorhabditis elegans)
        
        alg-3 [cytosol] (Caenorhabditis elegans)
    - Duplex siRNA is loaded into Argonaute (Caenorhabditis elegans)
      - TARBP2,PRKRA RLC:duplex siRNA [cytosol] (Caenorhabditis elegans)
        
        PRKRA:DICER1:AGO1,2,3,4:duplex siRNA [cytosol] (Caenorhabditis elegans)
        
        PRKRA:DICER1:AGO1,2,3,4 [cytosol] (Caenorhabditis elegans)
        
        AGO1,2,3,4 [cytosol] (Caenorhabditis elegans)
        
        Homologues of EIF2C1 [cytosol] (Caenorhabditis elegans)
        
        alg-3 [cytosol] (Caenorhabditis elegans)
        
        RISC loading complex:duplex siRNA [cytosol] (Caenorhabditis elegans)
        
        RISC loading complex [cytosol] (Caenorhabditis elegans)
        
        AGO1,2,3,4 [cytosol] (Caenorhabditis elegans)
        
        Homologues of EIF2C1 [cytosol] (Caenorhabditis elegans)
        
        alg-3 [cytosol] (Caenorhabditis elegans)
      - TARBP2,PRKRA:DICER1:Pre-RISC (siRNA) [cytosol] (Caenorhabditis elegans)
        
        PRKRA:DICER1:Pre-RISC (siRNA) [cytosol] (Caenorhabditis elegans)
        
        pre-RISC (siRNA) [cytosol] (Caenorhabditis elegans)
        
        AGO1:duplex siRNA [cytosol] (Caenorhabditis elegans)
        
        Homologues of EIF2C1 [cytosol] (Caenorhabditis elegans)
        
        alg-3 [cytosol] (Caenorhabditis elegans)
        
        TARBP2:DICER1:Pre-RISC (siRNA) [cytosol] (Caenorhabditis elegans)
        
        pre-RISC (siRNA) [cytosol] (Caenorhabditis elegans)
        
        AGO1:duplex siRNA [cytosol] (Caenorhabditis elegans)
        
        Homologues of EIF2C1 [cytosol] (Caenorhabditis elegans)
        
        alg-3 [cytosol] (Caenorhabditis elegans)
    - Removal of siRNA passenger strand (Caenorhabditis elegans)
      - TARBP2,PRKRA:DICER1:Pre-RISC (siRNA) [cytosol] (Caenorhabditis elegans)
        
        PRKRA:DICER1:Pre-RISC (siRNA) [cytosol] (Caenorhabditis elegans)
        
        pre-RISC (siRNA) [cytosol] (Caenorhabditis elegans)
        
        AGO1:duplex siRNA [cytosol] (Caenorhabditis elegans)
        
        Homologues of EIF2C1 [cytosol] (Caenorhabditis elegans)
        
        alg-3 [cytosol] (Caenorhabditis elegans)
        
        TARBP2:DICER1:Pre-RISC (siRNA) [cytosol] (Caenorhabditis elegans)
        
        pre-RISC (siRNA) [cytosol] (Caenorhabditis elegans)
        
        AGO1:duplex siRNA [cytosol] (Caenorhabditis elegans)
        
        Homologues of EIF2C1 [cytosol] (Caenorhabditis elegans)
        
        alg-3 [cytosol] (Caenorhabditis elegans)
      - TARBP2,PRKRA:DICER1:RISC (siRNA) [cytosol] (Caenorhabditis elegans)
        
        PRKRA:DICER1:RISC (siRNA) [cytosol] (Caenorhabditis elegans)
        
        RISC (siRNA) [cytosol] (Caenorhabditis elegans)
        
        AGO1:siRNA [cytosol] (Caenorhabditis elegans)
        
        Homologues of EIF2C1 [cytosol] (Caenorhabditis elegans)
        
        alg-3 [cytosol] (Caenorhabditis elegans)
        
        TARBP2:DICER1:RISC (siRNA) [cytosol] (Caenorhabditis elegans)
        
        RISC (siRNA) [cytosol] (Caenorhabditis elegans)
        
        AGO1:siRNA [cytosol] (Caenorhabditis elegans)
        
        Homologues of EIF2C1 [cytosol] (Caenorhabditis elegans)
        
        alg-3 [cytosol] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:G5ED77

Gene Names

alg-3

Reference Genes

BioGPS Gene:178106 alg-3

CTD Gene:178106 alg-3

ENSEMBL:WBGene00011910

Monarch:178106 alg-3

NCBI Gene:178106 alg-3

Wormbase:WBGene00011910

Reference Transcript

RefSeq:NM_069816.1 alg-3

Other Identifiers

178106

179788_s_at

18542420

CE_WBGene00011910_A

CE_WBGene00011910_B

CGZ0036015

GO:0003676

GO:0005515

T22B3.2

T22B3.2b_2344-2403_0.907_3_C

T22B3.2b_2545-2604_0.906_4_B

T22B3.2b_2736-2795_0.928_1_A

T22B3_2aP01601

T22B3_2aP02002

T22B3_2aP02754

WBGene00011910

Participates

as a member of

Homologues of EIF2C1 [cytosol] (Caenorhabditis elegans)

Other forms of this molecule

alg-3 [nucleoplasm]

alg-3 [cytosol]

Inferred From

EIF2C1 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_502217.1

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