Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
ced-3 [nucleoplasm]
Stable Identifier
R-CEL-211194
Type
Protein [EntityWithAccessionedSequence]
Species
Caenorhabditis elegans
Compartment
nucleoplasm
Synonyms
CASP3(29-175), P42573
Locations in the PathwayBrowser
Expand all
Programmed Cell Death (Caenorhabditis elegans)
Apoptosis (Caenorhabditis elegans)
Apoptotic execution phase (Caenorhabditis elegans)
Apoptosis induced DNA fragmentation (Caenorhabditis elegans)
Translocation of caspase-3 to the nucleus (Caenorhabditis elegans)
active caspase-3 [nucleoplasm] (Caenorhabditis elegans)
CASP3(29-175):CASP3(176-277) [nucleoplasm] (Caenorhabditis elegans)
ced-3 [nucleoplasm] (Caenorhabditis elegans)
External Reference Information
External Reference
UniProt:P42573
Gene Names
ced-3
Reference Genes
BioGPS Gene:178272 ced-3
CTD Gene:178272 ced-3
ENSEMBL:WBGene00000417
KEGG:cel:CELE_C48D1.2 ced-3
Monarch:178272 ced-3
NCBI Entrez Gene:178272 ced-3
UCSC:P42573 ced-3
Wormbase:WBGene00000417
Wormbase:WBGene00000417 ced-3
Reference Transcript
RefSeq:NM_001268779.3 ced-3
Other Identifiers
178272
GO:0004175
GO:0004197
GO:0005515
GO:0005634
GO:0005737
GO:0005739
GO:0006508
GO:0006915
GO:0008047
GO:0008233
GO:0008234
GO:0008303
GO:0008656
GO:0009792
GO:0010954
GO:0012501
GO:0016020
GO:0016540
GO:0016787
GO:0030042
GO:0030155
GO:0030163
GO:0031647
GO:0031965
GO:0040012
GO:0040028
GO:0040034
GO:0042659
GO:0042802
GO:0042981
GO:0043025
GO:0043204
GO:0043525
GO:0045202
GO:0046716
GO:0048471
GO:0048856
GO:0050807
GO:0050829
GO:0097194
GO:0098542
GO:0098772
GO:0098793
GO:0140608
GO:1900118
GO:1902742
GO:1904747
GO:1905803
GO:1905808
GO:1905845
Participates
as a component of
CASP3(29-175):CASP3(176-277) [nucleoplasm] (Caenorhabditis elegans)
Other forms of this molecule
ced-3 [cytosol]
ced-3 [cytosol]
ced-3 [cytosol]
ced-3 [cytosol]
ced-3 [cytosol]
ced-3 [cytosol]
ced-3 [nucleoplasm]
ced-3 [cytosol]
ced-3 [cytosol]
ced-3 [cytosol]
phospho-ced-3 [cytosol]
ced-3 [cytosol]
ced-3 [cytosol]
ced-3 [cytosol]
ced-3 [cytosol]
ced-3 [cytosol]
ced-3 [cytosol]
Inferred From
CASP3(29-175) [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_001255708.1
ENSEMBL
C48D1.2a.1
,
C48D1.2a.1
,
WBGene00000417
PRO
P42573
PDB
8JOL
,
4M9R
,
4M9S
,
4M9X
,
4M9Y
,
4M9Z
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P30429-2 CED-4
0.858
13
UniProt:P30429 CED4
0.835
10
UniProt:P42573
18
ced-3 [cytosol]
(R-CEL-622412)
ced-3 [cytosol]
(R-CEL-57033)
ced-3 [cytosol]
(R-CEL-622418)
ced-3 [cytosol]
(R-CEL-3371356)
ced-3 [cytosol]
(R-CEL-141646)
ced-3 [cytosol]
(R-CEL-141644)
ced-3 [nucleoplasm]
(R-CEL-211203)
ced-3 [nucleoplasm]
(R-CEL-211194)
ced-3 [cytosol]
(R-CEL-141638)
ced-3 [cytosol]
(R-CEL-141639)
ced-3 [cytosol]
(R-CEL-57021)
phospho-ced-3 [cytosol]
(R-CEL-198636)
ced-3 [cytosol]
(R-CEL-9686132)
ced-3 [cytosol]
(R-CEL-9710105)
ced-3 [cytosol]
(R-CEL-9710073)
ced-3 [cytosol]
(R-CEL-2976745)
ced-3 [cytosol]
(R-CEL-2976746)
ced-3 [cytosol]
(R-CEL-9818805)
0.753
7
UniProt:P41958
2
ced-9 [mitochondrial outer membrane]
(R-CEL-114236)
ced-9 [mitochondrial outer membrane]
(R-CEL-50757)
0.702
4
UniProt:G5ECW5 CSP3
0.602
3
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text