Reactome | cdk-8 [nucleoplasm]

cdk-8 [nucleoplasm]

Stable Identifier

R-CEL-212440

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

nucleoplasm

Synonyms

CDK8, P90866

Locations in the PathwayBrowser

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Gene expression (Transcription) (Caenorhabditis elegans)

- RNA Polymerase II Transcription (Caenorhabditis elegans)
  - Generic Transcription Pathway (Caenorhabditis elegans)
    - Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Caenorhabditis elegans)
      - SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription (Caenorhabditis elegans)
        
        Phosphorylation of SMAD2 and SMAD3 linker regions by CDK8 or CDK9 (Caenorhabditis elegans)
        
        CDK8:CCNC/ CDK9:CCNT [nucleoplasm] (Caenorhabditis elegans)
        
        CDK8:CCNC [nucleoplasm] (Caenorhabditis elegans)
        
        cdk-8 [nucleoplasm] (Caenorhabditis elegans)

Signal Transduction (Caenorhabditis elegans)

- Signaling by TGFB family members (Caenorhabditis elegans)
  - Signaling by TGF-beta Receptor Complex (Caenorhabditis elegans)
    - Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Caenorhabditis elegans)
      - SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription (Caenorhabditis elegans)
        
        Phosphorylation of SMAD2 and SMAD3 linker regions by CDK8 or CDK9 (Caenorhabditis elegans)
        
        CDK8:CCNC/ CDK9:CCNT [nucleoplasm] (Caenorhabditis elegans)
        
        CDK8:CCNC [nucleoplasm] (Caenorhabditis elegans)
        
        cdk-8 [nucleoplasm] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:P90866

Gene Names

cdk-8

Reference Genes

BioGPS Gene:172677 cdk-8

CTD Gene:172677 cdk-8

ENSEMBL:WBGene00000409

KEGG Gene (Caenorhabditis elegans):CELE_F39H11.3 cdk-8

Monarch:172677 cdk-8

NCBI Gene:172677 cdk-8

UCSC:P90866 cdk-8

Wormbase:WBGene00000409

Reference Transcript

RefSeq:NM_059956.6 cdk-8

Other Identifiers

172677

18455768

190709_at

A_12_P109841

CE32409

CE_WBGene00000409_A

CE_WBGene00000409_B

CGZ0020693

F39H11.3

F39H11.3_710-769_0.820_61_C

F39H11.3_825-884_0.891_25_B

F39H11.3_978-1037_0.897_21_A

F39H11_3P00308

F39H11_3P01090

F39H11_3P01465

GO:0003674

GO:0004672

GO:0005524

GO:0006464

GO:0006468

GO:0008150

GO:0016301

GO:0043167

WBGene00000409

cea2.c.03535

Participates

as a component of

CDK8:CCNC [nucleoplasm] (Caenorhabditis elegans)

Inferred From

CDK8 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_492357.2

IntEnz

2.7.11.23

PRO

P90866

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