Reactome | emb-9 [extracellular region]

emb-9 [extracellular region]

Stable Identifier

R-CEL-2127318

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

extracellular region

Synonyms

3x4Hyp-3Hyp-GalHyl-COL4A2(184-1712), P17139

Locations in the PathwayBrowser

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Extracellular matrix organization (Caenorhabditis elegans)

- Collagen formation (Caenorhabditis elegans)
  - Assembly of collagen fibrils and other multimeric structures (Caenorhabditis elegans)
    - Crosslinking of collagen fibrils (Caenorhabditis elegans)
      - Collagen type IV sulfilimine cross-linking by peroxidasin (Caenorhabditis elegans)
        
        Collagen IV [extracellular region] (Caenorhabditis elegans)
        
        Collagen type IV alpha1.alpha1.alpha2 network [extracellular region] (Caenorhabditis elegans)
        
        Tropocollagen alpha-1(IV).alpha-1(IV).alpha-2(IV) [extracellular region] (Caenorhabditis elegans)
        
        emb-9 [extracellular region] (Caenorhabditis elegans)
        
        Collagen type IV alpha1.alpha2.alpha5.alpha6 network [extracellular region] (Caenorhabditis elegans)
        
        Tropocollagen alpha-1(IV).alpha-2(IV).alpha-5(IV).alpha-6(IV) [extracellular region] (Caenorhabditis elegans)
        
        emb-9 [extracellular region] (Caenorhabditis elegans)
        
        Collagen type IV networks with sulfilimine cross-links [extracellular region] (Caenorhabditis elegans)
        
        Sulfilimine-containing collagen type IV alpha1.alpha1.alpha2 network [extracellular region] (Caenorhabditis elegans)
        
        Tropocollagen alpha-1(IV).alpha-1(IV).alpha-2(IV) with or without sulfiliminyl cross-links [extracellular region] (Caenorhabditis elegans)
        
        Tropocollagen alpha-1(IV).alpha-1(IV).alpha-2(IV) [extracellular region] (Caenorhabditis elegans)
        
        emb-9 [extracellular region] (Caenorhabditis elegans)
        
        Sulfilimine-containing collagen type IV alpha1.alpha2.alpha5.alpha6 network [extracellular region] (Caenorhabditis elegans)
        
        Collagen type IV alpha1.alpha2.alpha5.alpha6 tropocollagens with or without sulfilimine cross-links [extracellular region] (Caenorhabditis elegans)
        
        Tropocollagen alpha-1(IV).alpha-1(IV).alpha-2(IV) with or without sulfiliminyl cross-links [extracellular region] (Caenorhabditis elegans)
        
        Tropocollagen alpha-1(IV).alpha-1(IV).alpha-2(IV) [extracellular region] (Caenorhabditis elegans)
        
        emb-9 [extracellular region] (Caenorhabditis elegans)
    - Formation of collagen networks (Caenorhabditis elegans)
      - Collagen networks [extracellular region] (Caenorhabditis elegans)
        
        Collagen IV [extracellular region] (Caenorhabditis elegans)
        
        Collagen type IV alpha1.alpha1.alpha2 network [extracellular region] (Caenorhabditis elegans)
        
        Tropocollagen alpha-1(IV).alpha-1(IV).alpha-2(IV) [extracellular region] (Caenorhabditis elegans)
        
        emb-9 [extracellular region] (Caenorhabditis elegans)
        
        Collagen type IV alpha1.alpha2.alpha5.alpha6 network [extracellular region] (Caenorhabditis elegans)
        
        Tropocollagen alpha-1(IV).alpha-2(IV).alpha-5(IV).alpha-6(IV) [extracellular region] (Caenorhabditis elegans)
        
        emb-9 [extracellular region] (Caenorhabditis elegans)
      - Network forming tropocollagens [extracellular region] (Caenorhabditis elegans)
        
        Tropocollagen alpha-1(IV).alpha-1(IV).alpha-2(IV) [extracellular region] (Caenorhabditis elegans)
        
        emb-9 [extracellular region] (Caenorhabditis elegans)
- Degradation of the extracellular matrix (Caenorhabditis elegans)
  - Collagen degradation (Caenorhabditis elegans)
    - Collagen type IV degradation by MMP2,3,4,9,10,12 (Caenorhabditis elegans)
      - Collagen IV [extracellular region] (Caenorhabditis elegans)
        
        Collagen type IV alpha1.alpha1.alpha2 network [extracellular region] (Caenorhabditis elegans)
        
        Tropocollagen alpha-1(IV).alpha-1(IV).alpha-2(IV) [extracellular region] (Caenorhabditis elegans)
        
        emb-9 [extracellular region] (Caenorhabditis elegans)
        
        Collagen type IV alpha1.alpha2.alpha5.alpha6 network [extracellular region] (Caenorhabditis elegans)
        
        Tropocollagen alpha-1(IV).alpha-2(IV).alpha-5(IV).alpha-6(IV) [extracellular region] (Caenorhabditis elegans)
        
        emb-9 [extracellular region] (Caenorhabditis elegans)
- FN1 binds Collagen types I-V, VII (Caenorhabditis elegans)
  - Collagen IV [extracellular region] (Caenorhabditis elegans)
    - Collagen type IV alpha1.alpha1.alpha2 network [extracellular region] (Caenorhabditis elegans)
      - Tropocollagen alpha-1(IV).alpha-1(IV).alpha-2(IV) [extracellular region] (Caenorhabditis elegans)
        
        emb-9 [extracellular region] (Caenorhabditis elegans)
    - Collagen type IV alpha1.alpha2.alpha5.alpha6 network [extracellular region] (Caenorhabditis elegans)
      - Tropocollagen alpha-1(IV).alpha-2(IV).alpha-5(IV).alpha-6(IV) [extracellular region] (Caenorhabditis elegans)
        
        emb-9 [extracellular region] (Caenorhabditis elegans)
  - FN1(32-2386):Collagen types I-V, VII [extracellular region] (Caenorhabditis elegans)
    - Collagen IV [extracellular region] (Caenorhabditis elegans)
      - Collagen type IV alpha1.alpha1.alpha2 network [extracellular region] (Caenorhabditis elegans)
        
        Tropocollagen alpha-1(IV).alpha-1(IV).alpha-2(IV) [extracellular region] (Caenorhabditis elegans)
        
        emb-9 [extracellular region] (Caenorhabditis elegans)
      - Collagen type IV alpha1.alpha2.alpha5.alpha6 network [extracellular region] (Caenorhabditis elegans)
        
        Tropocollagen alpha-1(IV).alpha-2(IV).alpha-5(IV).alpha-6(IV) [extracellular region] (Caenorhabditis elegans)
        
        emb-9 [extracellular region] (Caenorhabditis elegans)
- Non-integrin membrane-ECM interactions (Caenorhabditis elegans)
  - DDR1 binds collagen type I, II, III, IV, V, XI fibrils (Caenorhabditis elegans)
    - Collagen IV [extracellular region] (Caenorhabditis elegans)
      - Collagen type IV alpha1.alpha1.alpha2 network [extracellular region] (Caenorhabditis elegans)
        
        Tropocollagen alpha-1(IV).alpha-1(IV).alpha-2(IV) [extracellular region] (Caenorhabditis elegans)
        
        emb-9 [extracellular region] (Caenorhabditis elegans)
      - Collagen type IV alpha1.alpha2.alpha5.alpha6 network [extracellular region] (Caenorhabditis elegans)
        
        Tropocollagen alpha-1(IV).alpha-2(IV).alpha-5(IV).alpha-6(IV) [extracellular region] (Caenorhabditis elegans)
        
        emb-9 [extracellular region] (Caenorhabditis elegans)
    - DDR1 dimer:Collagen type I, II, III, IV, V, XI fibrils [plasma membrane] (Caenorhabditis elegans)
      - Collagen IV [extracellular region] (Caenorhabditis elegans)
        
        Collagen type IV alpha1.alpha1.alpha2 network [extracellular region] (Caenorhabditis elegans)
        
        Tropocollagen alpha-1(IV).alpha-1(IV).alpha-2(IV) [extracellular region] (Caenorhabditis elegans)
        
        emb-9 [extracellular region] (Caenorhabditis elegans)
        
        Collagen type IV alpha1.alpha2.alpha5.alpha6 network [extracellular region] (Caenorhabditis elegans)
        
        Tropocollagen alpha-1(IV).alpha-2(IV).alpha-5(IV).alpha-6(IV) [extracellular region] (Caenorhabditis elegans)
        
        emb-9 [extracellular region] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:P17139

Gene Names

emb-9

Reference Genes

BioGPS Gene:176314 emb-9

CTD Gene:176314 emb-9

ENSEMBL:WBGene00001263

KEGG Gene (Caenorhabditis elegans):CELE_K04H4.1 emb-9

Monarch:176314 emb-9

NCBI Gene:176314 emb-9

UCSC:P17139 emb-9

Wormbase:WBGene00001263

Reference Transcript

Other Identifiers

173790_at

176314

18525610

190353_s_at

A_12_P105661

CE32462

CE_WBGene00001263_A

CGZ0027869

GO:0005198

GO:0005201

GO:0005581

GO:0032991

K04H4.1

K04H4.1a_4369-4428_0.850_48_C

K04H4.1a_4847-4906_0.761_106_B

K04H4.1a_5236-5295_0.975_1_A

K04H4_1aP04598

K04H4_1aP04788

K04H4_1aP04969

WBGene00001263

cea2.p.67964

Participates

as a component of

Other forms of this molecule

emb-9 [endoplasmic reticulum lumen]

emb-9 [extracellular region]

emb-9 [plasma membrane]

emb-9 [extracellular region]

Inferred From

Collagen alpha-2(IV) chains [extracellular region] (Homo sapiens)

3x4Hyp-3Hyp-GalHyl-COL4A2(184-1712) [extracellular region] (Homo sapiens)

Modified Residues

Name

(2S,4R)-4-hydroxyproline at unknown position

PsiMod Name

(2S,4R)-4-hydroxyproline

PsiMod Definition

A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline

Name

(2S,4R)-4-hydroxyproline at unknown position

PsiMod Name

(2S,4R)-4-hydroxyproline

PsiMod Definition

A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline

Name

(2S,4R)-4-hydroxyproline at unknown position

PsiMod Name

(2S,4R)-4-hydroxyproline

PsiMod Definition

A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline

Name

(2S,3S)-3-hydroxyproline at unknown position

PsiMod Name

(2S,3S)-3-hydroxyproline

PsiMod Definition

A protein modification that effectively converts an L-proline residue to 3-hydroxy-L-proline.

Name

O5-galactosyl-L-hydroxylysine at unknown position

PsiMod Name

O5-galactosyl-L-hydroxylysine

PsiMod Definition

A protein modification that effectively converts an L-lysine residue to O5-galactosyl-L-hydroxylysine.

Cross References

RefSeq

NP_001022662.2, NP_001022663.1

PRO

P17139

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