Reactome | pat-3 [plasma membrane]

pat-3 [plasma membrane]

Stable Identifier

R-CEL-215951

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

plasma membrane

Synonyms

ITGB6, Q27874

Locations in the PathwayBrowser

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Extracellular matrix organization (Caenorhabditis elegans)

- ECM proteoglycans (Caenorhabditis elegans)
  - TNC binds Integrin alphaVbeta3, alphaVbeta6, alpha2beta1, alpha7beta1, alpha8beta1, alpha9beta1, alphaXbeta1 (Caenorhabditis elegans)
    - Integrin alphaVbeta3, alphaVbeta6, alpha2beta1, alpha7beta1, alpha8beta1, alpha9beta1, alphaXbeta1 [plasma membrane] (Caenorhabditis elegans)
      - Integrin alphaVbeta6 [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of ITGB6 [plasma membrane] (Caenorhabditis elegans)
        
        pat-3 [plasma membrane] (Caenorhabditis elegans)
    - TNC:Integrin alphaVbeta3, alphaVbeta6, alpha2beta1, alpha7beta1, alpha8beta1, alpha9beta1, alphaXbeta1 [plasma membrane] (Caenorhabditis elegans)
      - Integrin alphaVbeta3, alphaVbeta6, alpha2beta1, alpha7beta1, alpha8beta1, alpha9beta1, alphaXbeta1 [plasma membrane] (Caenorhabditis elegans)
        
        Integrin alphaVbeta6 [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of ITGB6 [plasma membrane] (Caenorhabditis elegans)
        
        pat-3 [plasma membrane] (Caenorhabditis elegans)
- Elastic fibre formation (Caenorhabditis elegans)
  - Molecules associated with elastic fibres (Caenorhabditis elegans)
    - Latent TGF-beta-1 binds integrins (Caenorhabditis elegans)
      - LAP1 binding-integrins [plasma membrane] (Caenorhabditis elegans)
        
        Integrin alphaVbeta6 [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of ITGB6 [plasma membrane] (Caenorhabditis elegans)
        
        pat-3 [plasma membrane] (Caenorhabditis elegans)
      - LTBP1:TGFB1:LAP1:LAP1-binding integrins [plasma membrane] (Caenorhabditis elegans)
        
        LAP1 binding-integrins [plasma membrane] (Caenorhabditis elegans)
        
        Integrin alphaVbeta6 [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of ITGB6 [plasma membrane] (Caenorhabditis elegans)
        
        pat-3 [plasma membrane] (Caenorhabditis elegans)
    - Latent TGF-beta-3 binds integrins (Caenorhabditis elegans)
      - LAP3-binding integrins [plasma membrane] (Caenorhabditis elegans)
        
        Integrin alphaVbeta6 [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of ITGB6 [plasma membrane] (Caenorhabditis elegans)
        
        pat-3 [plasma membrane] (Caenorhabditis elegans)
      - TGF-beta-3:LAP3:LAP3-binding integrins [plasma membrane] (Caenorhabditis elegans)
        
        LAP3-binding integrins [plasma membrane] (Caenorhabditis elegans)
        
        Integrin alphaVbeta6 [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of ITGB6 [plasma membrane] (Caenorhabditis elegans)
        
        pat-3 [plasma membrane] (Caenorhabditis elegans)
- Integrin cell surface interactions (Caenorhabditis elegans)
  - Integrins alpha4beta1, alpha8beta1, alphaVbeta1, alphaVbeta3, alphaVbeta6 bind Fibronectin matrix (Caenorhabditis elegans)
    - Integrin alpha4beta1, alpha8beta1, alphaVbeta1, alphaVbeta3, alphaVbeta6 [plasma membrane] (Caenorhabditis elegans)
      - Integrin alphaVbeta6 [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of ITGB6 [plasma membrane] (Caenorhabditis elegans)
        
        pat-3 [plasma membrane] (Caenorhabditis elegans)
    - Integrin alpha4beta1, alpha8beta1, alphaVbeta6:Fibronectin matrix [plasma membrane] (Caenorhabditis elegans)
      - Integrin alpha4beta1, alpha8beta1, alphaVbeta1, alphaVbeta3, alphaVbeta6 [plasma membrane] (Caenorhabditis elegans)
        
        Integrin alphaVbeta6 [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of ITGB6 [plasma membrane] (Caenorhabditis elegans)
        
        pat-3 [plasma membrane] (Caenorhabditis elegans)

Signal Transduction (Caenorhabditis elegans)

- Signaling by TGFB family members (Caenorhabditis elegans)
  - Signaling by TGF-beta Receptor Complex (Caenorhabditis elegans)
    - TGF-beta receptor signaling activates SMADs (Caenorhabditis elegans)
      - Latent TGF-beta-1 binds integrins (Caenorhabditis elegans)
        
        LAP1 binding-integrins [plasma membrane] (Caenorhabditis elegans)
        
        Integrin alphaVbeta6 [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of ITGB6 [plasma membrane] (Caenorhabditis elegans)
        
        pat-3 [plasma membrane] (Caenorhabditis elegans)
        
        LTBP1:TGFB1:LAP1:LAP1-binding integrins [plasma membrane] (Caenorhabditis elegans)
        
        LAP1 binding-integrins [plasma membrane] (Caenorhabditis elegans)
        
        Integrin alphaVbeta6 [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of ITGB6 [plasma membrane] (Caenorhabditis elegans)
        
        pat-3 [plasma membrane] (Caenorhabditis elegans)
      - Latent TGF-beta-3 binds integrins (Caenorhabditis elegans)
        
        LAP3-binding integrins [plasma membrane] (Caenorhabditis elegans)
        
        Integrin alphaVbeta6 [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of ITGB6 [plasma membrane] (Caenorhabditis elegans)
        
        pat-3 [plasma membrane] (Caenorhabditis elegans)
        
        TGF-beta-3:LAP3:LAP3-binding integrins [plasma membrane] (Caenorhabditis elegans)
        
        LAP3-binding integrins [plasma membrane] (Caenorhabditis elegans)
        
        Integrin alphaVbeta6 [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of ITGB6 [plasma membrane] (Caenorhabditis elegans)
        
        pat-3 [plasma membrane] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:Q27874

Gene Names

pat-3

Reference Genes

BioGPS Gene:175504 pat-3

CTD Gene:175504 pat-3

ENSEMBL:WBGene00003930

KEGG Gene (Caenorhabditis elegans):CELE_ZK1058.2 pat-3

Monarch:175504 pat-3

NCBI Gene:175504 pat-3

UCSC:Q27874 pat-3

Wormbase:WBGene00003930

Reference Transcript

RefSeq:NM_065386.5 pat-3

Other Identifiers

174553_at

175504

18531548

191710_at

A_12_P105791

CE01102

CE_WBGene00003930_A

CGZ0056184

WBGene00003930

ZK1058.2

ZK1058.2_1858-1917_0.924_9_C

ZK1058.2_1938-1997_0.931_7_B

ZK1058.2_2008-2067_0.933_6_A

ZK1058_2P01212

ZK1058_2P01581

ZK1058_2P01976

cea2.p.83365

Participates

as a member of

Homologues of ITGB6 [plasma membrane] (Caenorhabditis elegans)

Other forms of this molecule

phospho-pat-3 [plasma membrane]

pat-3 [platelet alpha granule membrane]

pat-3 [specific granule membrane]

pat-3 [ficolin-1-rich granule membrane]

pat-3 [tertiary granule membrane]

pat-3 [phagocytic vesicle]

pat-3 [plasma membrane]

Inferred From

ITGB6 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_497787.1

PRO

Q27874

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