Reactome | NCKIPSD [cytosol]

NCKIPSD [cytosol]

Stable Identifier

R-CEL-2197671

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

cytosol

Synonyms

Q9N372

Locations in the PathwayBrowser

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Immune System (Caenorhabditis elegans)

- Innate Immune System (Caenorhabditis elegans)
  - Fcgamma receptor (FCGR) dependent phagocytosis (Caenorhabditis elegans)
    - Regulation of actin dynamics for phagocytic cup formation (Caenorhabditis elegans)
      - (WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Caenorhabditis elegans)
        
        Mother filament:branching complex [cytosol] (Caenorhabditis elegans)
        
        WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Caenorhabditis elegans)
        
        WAVE2, WASP, N-WASP [plasma membrane] (Caenorhabditis elegans)
        
        CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Caenorhabditis elegans)
        
        SH3 domain proteins [cytosol] (Caenorhabditis elegans)
        
        NCKIPSD [cytosol] (Caenorhabditis elegans)
        
        WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Caenorhabditis elegans)
        
        WAVE2, WASP, N-WASP [plasma membrane] (Caenorhabditis elegans)
        
        CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Caenorhabditis elegans)
        
        SH3 domain proteins [cytosol] (Caenorhabditis elegans)
        
        NCKIPSD [cytosol] (Caenorhabditis elegans)
      - Detachment of WASP/WAVE (Caenorhabditis elegans)
        
        Mother filament:branching complex [cytosol] (Caenorhabditis elegans)
        
        WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Caenorhabditis elegans)
        
        WAVE2, WASP, N-WASP [plasma membrane] (Caenorhabditis elegans)
        
        CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Caenorhabditis elegans)
        
        SH3 domain proteins [cytosol] (Caenorhabditis elegans)
        
        NCKIPSD [cytosol] (Caenorhabditis elegans)
        
        WAVE2, WASP, N-WASP [plasma membrane] (Caenorhabditis elegans)
        
        CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Caenorhabditis elegans)
        
        SH3 domain proteins [cytosol] (Caenorhabditis elegans)
        
        NCKIPSD [cytosol] (Caenorhabditis elegans)
      - Src phosphorylate WASP,N-WASP (Caenorhabditis elegans)
        
        CDC42:GTP:WASP/N-WASP:WIP:SH3 proteins [plasma membrane] (Caenorhabditis elegans)
        
        SH3 domain proteins [cytosol] (Caenorhabditis elegans)
        
        NCKIPSD [cytosol] (Caenorhabditis elegans)
        
        CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Caenorhabditis elegans)
        
        SH3 domain proteins [cytosol] (Caenorhabditis elegans)
        
        NCKIPSD [cytosol] (Caenorhabditis elegans)

Signal Transduction (Caenorhabditis elegans)

- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Caenorhabditis elegans)
  - Signaling by Rho GTPases (Caenorhabditis elegans)
    - RHO GTPase Effectors (Caenorhabditis elegans)
      - RHO GTPases Activate WASPs and WAVEs (Caenorhabditis elegans)
        
        (WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Caenorhabditis elegans)
        
        Mother filament:branching complex [cytosol] (Caenorhabditis elegans)
        
        WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Caenorhabditis elegans)
        
        WAVE2, WASP, N-WASP [plasma membrane] (Caenorhabditis elegans)
        
        CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Caenorhabditis elegans)
        
        SH3 domain proteins [cytosol] (Caenorhabditis elegans)
        
        NCKIPSD [cytosol] (Caenorhabditis elegans)
        
        WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Caenorhabditis elegans)
        
        WAVE2, WASP, N-WASP [plasma membrane] (Caenorhabditis elegans)
        
        CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Caenorhabditis elegans)
        
        SH3 domain proteins [cytosol] (Caenorhabditis elegans)
        
        NCKIPSD [cytosol] (Caenorhabditis elegans)
        
        Detachment of WASP/WAVE (Caenorhabditis elegans)
        
        Mother filament:branching complex [cytosol] (Caenorhabditis elegans)
        
        WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Caenorhabditis elegans)
        
        WAVE2, WASP, N-WASP [plasma membrane] (Caenorhabditis elegans)
        
        CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Caenorhabditis elegans)
        
        SH3 domain proteins [cytosol] (Caenorhabditis elegans)
        
        NCKIPSD [cytosol] (Caenorhabditis elegans)
        
        WAVE2, WASP, N-WASP [plasma membrane] (Caenorhabditis elegans)
        
        CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Caenorhabditis elegans)
        
        SH3 domain proteins [cytosol] (Caenorhabditis elegans)
        
        NCKIPSD [cytosol] (Caenorhabditis elegans)
        
        Src phosphorylate WASP,N-WASP (Caenorhabditis elegans)
        
        CDC42:GTP:WASP/N-WASP:WIP:SH3 proteins [plasma membrane] (Caenorhabditis elegans)
        
        SH3 domain proteins [cytosol] (Caenorhabditis elegans)
        
        NCKIPSD [cytosol] (Caenorhabditis elegans)
        
        CDC42:GTP:p-Y-WASP/p-Y-WASL:WIP:SH3 proteins [plasma membrane] (Caenorhabditis elegans)
        
        SH3 domain proteins [cytosol] (Caenorhabditis elegans)
        
        NCKIPSD [cytosol] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:Q9N372

Reference Genes

BioGPS Gene:190307

ENSEMBL:WBGene00021923

KEGG:cel:CELE_Y55F3AM.5

Monarch:190307

NCBI Gene:190307

UCSC:Q9N372

Wormbase:WBGene00021923

Reference Transcript

RefSeq:NM_067620.4

Other Identifiers

18545258

186579_at

190307

A_12_P158470

A_12_P158471

CE25487

CGZ0013234

CGZ0049359

GO:0006897

GO:0016192

GO:0071933

WBGene00021923

Y55F3AM.5

Y55F3AM.5_527-586_0.926_4_C

Y55F3AM.5_794-853_0.928_3_B

Y55F3AM.5_925-984_0.959_1_A

Y55F3AM_5P00064

Y55F3AM_5P00346

Y55F3AM_5P00789

cea2.i.30597

Participates

as a member of

SH3 domain proteins [cytosol] (Caenorhabditis elegans)

Inferred From

NCKIPSD [cytosol] (Homo sapiens)

Cross References

ENSEMBL

Y55F3AM.5.1, WBGene00021923, Y55F3AM.5.1

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