Reactome | dnj-25 [cytosol]

dnj-25 [cytosol]

Stable Identifier

R-CEL-264472

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

cytosol

Synonyms

DNAJC6, A0A486WXP9

Locations in the PathwayBrowser

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Vesicle-mediated transport (Caenorhabditis elegans)

- Membrane Trafficking (Caenorhabditis elegans)
  - Clathrin-mediated endocytosis (Caenorhabditis elegans)
    - Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle (Caenorhabditis elegans)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
        
        dnj-25 [cytosol] (Caenorhabditis elegans)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
        
        dnj-25 [cytosol] (Caenorhabditis elegans)
    - Clathrin recruits auxilins to the clathrin-coated vesicle (Caenorhabditis elegans)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
        
        dnj-25 [cytosol] (Caenorhabditis elegans)
      - dnj-25 [cytosol] (Caenorhabditis elegans)
    - HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Caenorhabditis elegans)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
        
        dnj-25 [cytosol] (Caenorhabditis elegans)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
        
        dnj-25 [cytosol] (Caenorhabditis elegans)
    - RAB5 and GAPVD1 bind AP-2 (Caenorhabditis elegans)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
        
        PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)
        
        dnj-25 [cytosol] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:A0A486WXP9

Gene Names

dnj-25

Reference Genes

ENSEMBL:WBGene00001043

Wormbase:WBGene00001043

Other Identifiers

172017_x_at

172275_x_at

180356

18598130

A_12_P105565

CE27221

CE_WBGene00001043_A

CGZ0038689

W07A8.3

W07A8.3_2133-2192_0.890_14_A

W07A8.3_2265-2324_0.934_3_B

W07A8.3_2320-2379_0.951_1_C

W07A8_3P01418

W07A8_3P01902

W07A8_3P02263

WBGene00001043

cea2.c.39386

Participates

as a component of

as an input of

Clathrin recruits auxilins to the clathrin-coated vesicle (Caenorhabditis elegans)

Other forms of this molecule

dnj-25 [cytosol]

dnj-25 [Golgi membrane]

dnj-25 [cytoplasmic vesicle membrane]

Inferred From

GAK,DNAJC6 [cytosol] (Homo sapiens)

DNAJC6 [cytosol] (Homo sapiens)