Reactome | lin-44 [extracellular region]

lin-44 [extracellular region]

Stable Identifier

R-CEL-3247797-2

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

extracellular region

Synonyms

N4GlycoAsn-PalmS WNT11, Q27886

Locations in the PathwayBrowser

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Signal Transduction (Caenorhabditis elegans)

- Signaling by WNT (Caenorhabditis elegans)
  - Beta-catenin independent WNT signaling (Caenorhabditis elegans)
    - Ca2+ pathway (Caenorhabditis elegans)
      - G-protein subunits dissociate from WNT:FZD complex (Caenorhabditis elegans)
        
        WNT5A/11:FZD [plasma membrane] (Caenorhabditis elegans)
        
        WNT5A/WNT11 [extracellular region] (Caenorhabditis elegans)
        
        Homologues of N4GlycoAsn-PalmS WNT11 [extracellular region] (Caenorhabditis elegans)
        
        lin-44 [extracellular region] (Caenorhabditis elegans)
        
        WNT5A/11:FZD:G-protein (alpha o/t2) active [plasma membrane] (Caenorhabditis elegans)
        
        WNT5A/11:FZD [plasma membrane] (Caenorhabditis elegans)
        
        WNT5A/WNT11 [extracellular region] (Caenorhabditis elegans)
        
        Homologues of N4GlycoAsn-PalmS WNT11 [extracellular region] (Caenorhabditis elegans)
        
        lin-44 [extracellular region] (Caenorhabditis elegans)
      - WNT:FZD complex promotes G-protein nucleotide exchange (Caenorhabditis elegans)
        
        WNT5A/11:FZD:G-protein (alpha o/t2) active [plasma membrane] (Caenorhabditis elegans)
        
        WNT5A/11:FZD [plasma membrane] (Caenorhabditis elegans)
        
        WNT5A/WNT11 [extracellular region] (Caenorhabditis elegans)
        
        Homologues of N4GlycoAsn-PalmS WNT11 [extracellular region] (Caenorhabditis elegans)
        
        lin-44 [extracellular region] (Caenorhabditis elegans)
        
        WNT5A/11:FZD:G-protein (alpha o/t2) inactive [plasma membrane] (Caenorhabditis elegans)
        
        WNT5A/11:FZD [plasma membrane] (Caenorhabditis elegans)
        
        WNT5A/WNT11 [extracellular region] (Caenorhabditis elegans)
        
        Homologues of N4GlycoAsn-PalmS WNT11 [extracellular region] (Caenorhabditis elegans)
        
        lin-44 [extracellular region] (Caenorhabditis elegans)
    - PCP/CE pathway (Caenorhabditis elegans)
      - DVL is recruited to the receptor (Caenorhabditis elegans)
        
        WNT:FZD [plasma membrane] (Caenorhabditis elegans)
        
        PCP pathway WNTs [extracellular region] (Caenorhabditis elegans)
        
        Homologues of N4GlycoAsn-PalmS WNT11 [extracellular region] (Caenorhabditis elegans)
        
        lin-44 [extracellular region] (Caenorhabditis elegans)
        
        WNT:FZD:pDVL [plasma membrane] (Caenorhabditis elegans)
        
        WNT:FZD [plasma membrane] (Caenorhabditis elegans)
        
        PCP pathway WNTs [extracellular region] (Caenorhabditis elegans)
        
        Homologues of N4GlycoAsn-PalmS WNT11 [extracellular region] (Caenorhabditis elegans)
        
        lin-44 [extracellular region] (Caenorhabditis elegans)
  - WNT ligand biogenesis and trafficking (Caenorhabditis elegans)
    - secretion of WNT ligands (Caenorhabditis elegans)
      - WNTs [extracellular region] (Caenorhabditis elegans)
        
        Homologues of N4GlycoAsn-PalmS WNT11 [extracellular region] (Caenorhabditis elegans)
        
        lin-44 [extracellular region] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:Q27886

Gene Names

lin-44

Reference Genes

BioGPS Gene:171994 lin-44

ENSEMBL:WBGene00003029

KEGG:cel:CELE_E01A2.3 lin-44

Monarch:171994 lin-44

NCBI Gene:171994 lin-44

UCSC:Q27886 lin-44

Wormbase:WBGene00003029

Wormbase:WBGene00003029 lin-44

Reference Transcript

RefSeq:NM_001025910.4 lin-44

Other Identifiers

171994

176619_s_at

18453760

A_12_P119612

A_12_P138550

A_12_P138551

A_12_P138552

A_12_P138553

A_12_P138554

CE24870

CE_WBGene00003029_A

CE_WBGene00003029_B

CGZ0013978

CGZ0013979

E01A2.3

E01A2.3a_532-591_0.934_6_C

E01A2.3a_666-725_0.942_3_B

E01A2.3a_752-811_0.946_1_A

E01A2_3aP00068

E01A2_3aP00311

E01A2_3aP00386

E01A2_3bP00142

E01A2_3bP00285

E01A2_3bP00416

GO:0001764

GO:0005102

GO:0005109

GO:0005125

GO:0005576

GO:0005615

GO:0007163

GO:0007275

GO:0008356

GO:0010623

GO:0012501

GO:0016055

GO:0030154

GO:0030182

GO:0040025

GO:0040028

GO:0045138

GO:0045165

GO:0045724

GO:0046662

GO:0048018

GO:0048699

GO:0048856

GO:0048870

GO:0050775

GO:0060070

GO:0060573

GO:0097402

GO:0097475

GO:0098772

GO:1904936

GO:1905485

WBGene00003029

cea2.c.02007

Participates

as a member of

Homologues of N4GlycoAsn-PalmS WNT11 [extracellular region] (Caenorhabditis elegans)

Other forms of this molecule

lin-44 [extracellular exosome]

lin-44 [endocytic vesicle membrane]

lin-44 [endoplasmic reticulum lumen]

lin-44 [Golgi lumen]

lin-44 [plasma membrane]

Inferred From

N4GlycoAsn-PalmS WNT11 [extracellular region] (Homo sapiens)

Modified Residues

Name

N4-glycosyl-L-asparagine at unknown position

PsiMod Name

N4-glycosyl-L-asparagine

PsiMod Definition

A protein modification that effectively converts an L-asparagine residue to an N4-glycosyl-L-asparagine.

Name

O-palmitoleyl-L-serine at 215 (in Homo sapiens)

Coordinate

215

PsiMod Name

O-palmitoleyl-L-serine

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O-palmitoleyl-L-serine.

Cross References

RefSeq

NP_001021081.1

ENSEMBL

WBGene00003029, E01A2.3.1, E01A2.3.1

PRO

Q27886

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