Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
RAP1A [plasma membrane]
Stable Identifier
R-CEL-354118
Type
Protein [EntityWithAccessionedSequence]
Species
Caenorhabditis elegans
Compartment
plasma membrane
Synonyms
Q18246
Locations in the PathwayBrowser
Expand all
Hemostasis (Caenorhabditis elegans)
Platelet activation, signaling and aggregation (Caenorhabditis elegans)
Platelet Aggregation (Plug Formation) (Caenorhabditis elegans)
Integrin signaling (Caenorhabditis elegans)
Activation of Rap1 by cytosolic GEFs (Caenorhabditis elegans)
RAP1:GDP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Activation of Rap1 by membrane-associated GEFs (Caenorhabditis elegans)
RAP1:GDP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Activation of Talin (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Autophosphorylation of PTK2 at Y397 (Caenorhabditis elegans)
Talin:RIAM complex: ECM ligands:Integrin alphaIIb beta3:Active (p-Y419)- SRC:PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: alphaIIb beta3:Active p-Y419-SRC:pY397-PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Autophosphorylation of SRC (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Clustering of Integrin alphaIIb beta3 complexes (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:p(Y530)-SRC:CSK) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
GRB2:SOS provides linkage to MAPK signaling for Integrins (Caenorhabditis elegans)
Interaction of SOS with GRB2 bound to FADK1 (Caenorhabditis elegans)
GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
GRB2:SOS:p-PTK2:Focal adhesion [plasma membrane] (Caenorhabditis elegans)
GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Recruitment of GRB2 to p-PTK2 (Caenorhabditis elegans)
GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3 activation (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Interaction of integrin alphaIIb beta3 with Fibrinogen (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Phosphorylation of pPTK2 by SRC (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: alphaIIb beta3:Active p-Y419-SRC:pY397-PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Release of CSK from SRC (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:Inactive (p-Y530)-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:p(Y530)-SRC:CSK) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow (Caenorhabditis elegans)
Integrin alpha IIb beta 3:p-Y530-SRC:CSK:Talin:RIAM complex:p-Y427-SHC [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta 3:p(Y530)-SRC:CSK:Talin:RIAM complex:SHC [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
SYK activation by SRC (Caenorhabditis elegans)
Talin:RIAM:ECM ligands:2X (Integrin alphaIIb beta3:Active (p-Y419)-SRC):SYK [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM:ECM ligands:2X(Integrin alphaIIb beta3:Active (p-Y419)-SRC):p(Y)-SYK [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
SYK binds to integrin alphaIIb beta3 (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM:ECM ligands:2X (Integrin alphaIIb beta3:Active (p-Y419)-SRC):SYK [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Translocation of PTK2 to Focal complexes (Caenorhabditis elegans)
Talin:RIAM complex: ECM ligands:Integrin alphaIIb beta3:Active (p-Y419)- SRC:PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Translocation of RIAM to plasma membrane (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Immune System (Caenorhabditis elegans)
Adaptive Immune System (Caenorhabditis elegans)
Rap1 signalling (Caenorhabditis elegans)
Activation of Rap1 by cytosolic GEFs (Caenorhabditis elegans)
RAP1:GDP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Activation of Rap1 by membrane-associated GEFs (Caenorhabditis elegans)
RAP1:GDP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Rap1 sequesters Raf1 to inhibit ERK cascade (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:Raf1 [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Rap1 signal termination by Rap1GAPs (Caenorhabditis elegans)
RAP1:GDP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Innate Immune System (Caenorhabditis elegans)
Neutrophil degranulation (Caenorhabditis elegans)
Exocytosis of azurophil granule membrane proteins (Caenorhabditis elegans)
Azurophil granule membrane proteins [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Exocytosis of specific granule membrane proteins (Caenorhabditis elegans)
Specific granule membrane proteins [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Metabolism (Caenorhabditis elegans)
Integration of energy metabolism (Caenorhabditis elegans)
Regulation of insulin secretion (Caenorhabditis elegans)
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion (Caenorhabditis elegans)
RAP1A exchanges GDP for GTP (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
RAP1A:GDP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Signal Transduction (Caenorhabditis elegans)
Integrin signaling (Caenorhabditis elegans)
Activation of Rap1 by cytosolic GEFs (Caenorhabditis elegans)
RAP1:GDP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Activation of Rap1 by membrane-associated GEFs (Caenorhabditis elegans)
RAP1:GDP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Activation of Talin (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Autophosphorylation of PTK2 at Y397 (Caenorhabditis elegans)
Talin:RIAM complex: ECM ligands:Integrin alphaIIb beta3:Active (p-Y419)- SRC:PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: alphaIIb beta3:Active p-Y419-SRC:pY397-PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Autophosphorylation of SRC (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Clustering of Integrin alphaIIb beta3 complexes (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:p(Y530)-SRC:CSK) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
GRB2:SOS provides linkage to MAPK signaling for Integrins (Caenorhabditis elegans)
Interaction of SOS with GRB2 bound to FADK1 (Caenorhabditis elegans)
GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
GRB2:SOS:p-PTK2:Focal adhesion [plasma membrane] (Caenorhabditis elegans)
GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Recruitment of GRB2 to p-PTK2 (Caenorhabditis elegans)
GRB2 bound to pPTK2 in Focal adhesion [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3 activation (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Interaction of integrin alphaIIb beta3 with Fibrinogen (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Phosphorylation of pPTK2 by SRC (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: Integrin alphaIIb beta3:Active (p-Y419)-SRC:p-6Y-PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: alphaIIb beta3:Active p-Y419-SRC:pY397-PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Release of CSK from SRC (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:Inactive (p-Y530)-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands: 2X(Integrin alphaIIb beta3:p(Y530)-SRC:CSK) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
SHC1 bound to integrin alphaIIb beta3 is phosphorylated somehow (Caenorhabditis elegans)
Integrin alpha IIb beta 3:p-Y530-SRC:CSK:Talin:RIAM complex:p-Y427-SHC [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta 3:p(Y530)-SRC:CSK:Talin:RIAM complex:SHC [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
SYK activation by SRC (Caenorhabditis elegans)
Talin:RIAM:ECM ligands:2X (Integrin alphaIIb beta3:Active (p-Y419)-SRC):SYK [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM:ECM ligands:2X(Integrin alphaIIb beta3:Active (p-Y419)-SRC):p(Y)-SYK [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
SYK binds to integrin alphaIIb beta3 (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM:ECM ligands:2X (Integrin alphaIIb beta3:Active (p-Y419)-SRC):SYK [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Translocation of PTK2 to Focal complexes (Caenorhabditis elegans)
Talin:RIAM complex: ECM ligands:Integrin alphaIIb beta3:Active (p-Y419)- SRC:PTK2 [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex:ECM ligands:2X(Integrin alphaIIb beta3:Active p-Y419-SRC) [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Translocation of RIAM to plasma membrane (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
MAPK family signaling cascades (Caenorhabditis elegans)
MAPK1/MAPK3 signaling (Caenorhabditis elegans)
RAF/MAP kinase cascade (Caenorhabditis elegans)
MAP2K and MAPK activation (Caenorhabditis elegans)
Dissociation of RAS:RAF complex (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Dual mechanism MAP2K inhibitors bind MAP2Ks (Caenorhabditis elegans)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Caenorhabditis elegans)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Dual mechanism MAPK inhibitors bind MAPKs (Caenorhabditis elegans)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Caenorhabditis elegans)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
MAP2Ks and MAPKs bind to the activated RAF complex (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
MAP2Ks phosphorylate MAPKs (Caenorhabditis elegans)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Caenorhabditis elegans)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Caenorhabditis elegans)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Caenorhabditis elegans)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
RAF phosphorylates MAP2K dimer (Caenorhabditis elegans)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Caenorhabditis elegans)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks (Caenorhabditis elegans)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Caenorhabditis elegans)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Single mechanism MAPK inhibitors bind phosphorylated MAPK (Caenorhabditis elegans)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK:single mechanism MAPK inhibitors [plasma membrane] (Caenorhabditis elegans)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Caenorhabditis elegans)
RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
Focal Adhesion/Focal contacts [plasma membrane] (Caenorhabditis elegans)
Vinculin bound to alphaIIbbeta3 [plasma membrane] (Caenorhabditis elegans)
Focal complex [plasma membrane] (Caenorhabditis elegans)
Integrin alphaIIb beta3:p-Y530-SRC:CSK:Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Talin:RIAM complex [plasma membrane] (Caenorhabditis elegans)
Rap1-GTP:PIP2:RIAM [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
Signaling by Receptor Tyrosine Kinases (Caenorhabditis elegans)
Signaling by MET (Caenorhabditis elegans)
MET promotes cell motility (Caenorhabditis elegans)
MET activates RAP1 and RAC1 (Caenorhabditis elegans)
RAPGEF1 activates RAP1 (Caenorhabditis elegans)
RAP1:GDP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
RAP1A [plasma membrane] (Caenorhabditis elegans)
External Reference Information
External Reference
UniProt:Q18246
Reference Genes
BioGPS Gene:177709
ENSEMBL:WBGene00004307
KEGG:cel:CELE_C27B7.8
Monarch:177709
NCBI Gene:177709
UCSC:Q18246
Wormbase:WBGene00004307
Wormbase:WBGene00004307
Reference Transcript
RefSeq:NM_069148.4
Other Identifiers
175485_at
177709
18549204
18549213
190315_at
A_12_P114734
A_12_P161193
A_12_P161194
A_12_P161195
A_12_P161196
A_12_P161197
C27B7.8
C27B7.8_249-308_0.943_7_B
C27B7.8_386-445_0.960_1_A
C27B7.8_61-120_0.872_25_C
C27B7.9_1-60_0.842_4_A
C27B7_8P00020
C27B7_8P00375
C27B7_8P00502
CE03037
CE_WBGene00004307_A
CGZ0006223
GO:0003824
GO:0003924
GO:0003925
GO:0005525
GO:0005886
GO:0007165
GO:0008544
GO:0016020
GO:0016787
GO:0019003
GO:0032486
GO:0040002
GO:0048856
GO:0071320
GO:0098772
GO:2000301
WBGene00004307
cea2.p.86864
Participates
as a component of
RAP1A:GDP [plasma membrane] (Caenorhabditis elegans)
RAP1:GDP [plasma membrane] (Caenorhabditis elegans)
RAP1:GTP [plasma membrane] (Caenorhabditis elegans)
as a member of
Azurophil granule membrane proteins [plasma membrane] (Caenorhabditis elegans)
Specific granule membrane proteins [plasma membrane] (Caenorhabditis elegans)
Other forms of this molecule
RAP1B [azurophil granule membrane]
RAP1A [specific granule membrane]
RAP1A [cytosol]
RAP1A [endosome membrane]
Inferred From
RAP1 [plasma membrane]
(Homo sapiens)
RAP1B [plasma membrane]
(Homo sapiens)
RAP1A [plasma membrane]
(Homo sapiens)
Cross References
RefSeq
NP_501549.1
ENSEMBL
C27B7.8.1
,
C27B7.8.1
,
WBGene00004307
PRO
Q18246
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
