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p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol]
Stable Identifier
R-CEL-3601577
Type
Complex
Species
Caenorhabditis elegans
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Signal Transduction (Caenorhabditis elegans)
Signaling by WNT (Caenorhabditis elegans)
Degradation of beta-catenin by the destruction complex (Caenorhabditis elegans)
AXIN is phosphorylated in the destruction complex (Caenorhabditis elegans)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Caenorhabditis elegans)
Association of beta-catenin with the destruction complex (Caenorhabditis elegans)
CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Caenorhabditis elegans)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Caenorhabditis elegans)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Caenorhabditis elegans)
Beta-catenin phosphorylation cascade (Caenorhabditis elegans)
Phosphorylation of beta-catenin at Ser45 by CK1 alpha (Caenorhabditis elegans)
CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Caenorhabditis elegans)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Caenorhabditis elegans)
p-S45 CTNNB1:p-Axin:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Caenorhabditis elegans)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Caenorhabditis elegans)
Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 (Caenorhabditis elegans)
p-S37,T41,S45 CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Caenorhabditis elegans)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Caenorhabditis elegans)
p-T41,S45 CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Caenorhabditis elegans)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Caenorhabditis elegans)
Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 (Caenorhabditis elegans)
p-S45 CTNNB1:p-Axin:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Caenorhabditis elegans)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Caenorhabditis elegans)
p-T41,S45 CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Caenorhabditis elegans)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Caenorhabditis elegans)
Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 (Caenorhabditis elegans)
p-S33,S37,T41,S45-beta-catenin:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Caenorhabditis elegans)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Caenorhabditis elegans)
p-S37,T41,S45 CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Caenorhabditis elegans)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Caenorhabditis elegans)
Phosphorylation of APC component of the destruction complex (Caenorhabditis elegans)
p-S33,S37,T41,S45-beta-catenin:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Caenorhabditis elegans)
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Caenorhabditis elegans)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
apr-1 [cytosol]
(Caenorhabditis elegans)
CSNK1A1 [cytosol]
(Caenorhabditis elegans)
Ghost homologue of AMER1 [cytosol]
(Caenorhabditis elegans)
Homologues of GSK3B [cytosol]
(Caenorhabditis elegans)
phospho-pry-1 [cytosol]
(Caenorhabditis elegans)
PP2A [cytosol]
(Caenorhabditis elegans)
Participates
as an input of
Association of beta-catenin with the destruction complex (Caenorhabditis elegans)
as an output of
AXIN is phosphorylated in the destruction complex (Caenorhabditis elegans)
as a component of
CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Caenorhabditis elegans)
p-S45 CTNNB1:p-Axin:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Caenorhabditis elegans)
p-T41,S45 CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Caenorhabditis elegans)
p-S37,T41,S45 CTNNB1:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Caenorhabditis elegans)
p-S33,S37,T41,S45-beta-catenin:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Caenorhabditis elegans)
Inferred From
p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol]
(Homo sapiens)
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