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ERBB2 [plasma membrane]
Stable Identifier
R-CEL-372889
Type
Protein [EntityWithAccessionedSequence]
Species
Caenorhabditis elegans
Compartment
plasma membrane
Synonyms
P24348
Locations in the PathwayBrowser
Expand all
Developmental Biology (Caenorhabditis elegans)
Nervous system development (Caenorhabditis elegans)
Axon guidance (Caenorhabditis elegans)
Semaphorin interactions (Caenorhabditis elegans)
Sema4D in semaphorin signaling (Caenorhabditis elegans)
Sema4D induced cell migration and growth-cone collapse (Caenorhabditis elegans)
Activation of Rho by LARG and PDZ-RhoGEF (Caenorhabditis elegans)
SEMA4D:ERBB2:p-Y-PLXNB1:RND1:ARHGEF11,ARHGEF12 [plasma membrane] (Caenorhabditis elegans)
SEMA4D:ERBB2:p-Y-PLXNB1:RND1 [plasma membrane] (Caenorhabditis elegans)
SEMA4D:ERBB2:p-Y-PLXNB1 [plasma membrane] (Caenorhabditis elegans)
ERBB2:p-Y-PLXNB1 [plasma membrane] (Caenorhabditis elegans)
ERBB2 [plasma membrane] (Caenorhabditis elegans)
LARG and PDZ-RhoGEF binds to Plexin-B1 (Caenorhabditis elegans)
SEMA4D:ERBB2:p-Y-PLXNB1:RND1 [plasma membrane] (Caenorhabditis elegans)
SEMA4D:ERBB2:p-Y-PLXNB1 [plasma membrane] (Caenorhabditis elegans)
ERBB2:p-Y-PLXNB1 [plasma membrane] (Caenorhabditis elegans)
ERBB2 [plasma membrane] (Caenorhabditis elegans)
SEMA4D:ERBB2:p-Y-PLXNB1:RND1:ARHGEF11,ARHGEF12 [plasma membrane] (Caenorhabditis elegans)
SEMA4D:ERBB2:p-Y-PLXNB1:RND1 [plasma membrane] (Caenorhabditis elegans)
SEMA4D:ERBB2:p-Y-PLXNB1 [plasma membrane] (Caenorhabditis elegans)
ERBB2:p-Y-PLXNB1 [plasma membrane] (Caenorhabditis elegans)
ERBB2 [plasma membrane] (Caenorhabditis elegans)
SEMA4D interacts with Plexin-B1:ErbB2 (Caenorhabditis elegans)
ERBB2 [plasma membrane] (Caenorhabditis elegans)
Plexin-B1:ErbB2 [plasma membrane] (Caenorhabditis elegans)
ERBB2 [plasma membrane] (Caenorhabditis elegans)
SEMA4D:ERBB2:p-Y-PLXNB1 [plasma membrane] (Caenorhabditis elegans)
ERBB2:p-Y-PLXNB1 [plasma membrane] (Caenorhabditis elegans)
ERBB2 [plasma membrane] (Caenorhabditis elegans)
Signal Transduction (Caenorhabditis elegans)
Signaling by Receptor Tyrosine Kinases (Caenorhabditis elegans)
Signaling by ERBB2 (Caenorhabditis elegans)
Downregulation of ERBB2 signaling (Caenorhabditis elegans)
CHIP (STUB1) mediates ubiquitination of ERBB2 (Caenorhabditis elegans)
ERBB2:ERBIN:HSP90:CDC37 [plasma membrane] (Caenorhabditis elegans)
ERBB2 [plasma membrane] (Caenorhabditis elegans)
Ub-ERBB2:ERBIN:Ub-HSP90:CDC37 [plasma membrane] (Caenorhabditis elegans)
ERBB2 [plasma membrane] (Caenorhabditis elegans)
CUL5 mediates ubiquitination of ERBB2 (Caenorhabditis elegans)
ERBB2:ERBIN:HSP90:CDC37 [plasma membrane] (Caenorhabditis elegans)
ERBB2 [plasma membrane] (Caenorhabditis elegans)
Ub-ERBB2:ERBIN:HSP90:CDC37 [plasma membrane] (Caenorhabditis elegans)
ERBB2 [plasma membrane] (Caenorhabditis elegans)
Drug-mediated inhibition of ERBB2 signaling (Caenorhabditis elegans)
ERBB2 binds TKIs (Caenorhabditis elegans)
ERBB2:ERBIN:HSP90:CDC37 [plasma membrane] (Caenorhabditis elegans)
ERBB2 [plasma membrane] (Caenorhabditis elegans)
ERBB2:TKIs:ERBIN:HSP90:CDC37 [plasma membrane] (Caenorhabditis elegans)
ERBB2:TKIs [plasma membrane] (Caenorhabditis elegans)
ERBB2 [plasma membrane] (Caenorhabditis elegans)
SRC family kinases phosphorylate ERBB2 (Caenorhabditis elegans)
EGF:EGFR:ERBB2 [plasma membrane] (Caenorhabditis elegans)
ERBB2 [plasma membrane] (Caenorhabditis elegans)
Trans-autophosphorylation of ERBB2 heterodimers (Caenorhabditis elegans)
EGF:EGFR:ERBB2 [plasma membrane] (Caenorhabditis elegans)
ERBB2 [plasma membrane] (Caenorhabditis elegans)
ERBB2:TKIs:ERBIN:HSP90:CDC37 [plasma membrane] (Caenorhabditis elegans)
ERBB2:TKIs [plasma membrane] (Caenorhabditis elegans)
ERBB2 [plasma membrane] (Caenorhabditis elegans)
ERBB2:trastuzumab:ERBIN:HSP90:CDC37 [plasma membrane] (Caenorhabditis elegans)
ERBB2:trastuzumab [plasma membrane] (Caenorhabditis elegans)
ERBB2 [plasma membrane] (Caenorhabditis elegans)
External Reference Information
External Reference
UniProt:P24348
Reference Genes
BioGPS Gene:174462
CTD Gene:174462
ENSEMBL:WBGene00002299
Monarch:174462
NCBI Gene:174462
UCSC:P24348
Wormbase:WBGene00002299
Reference Transcript
RefSeq:NM_063561.4
Other Identifiers
174462
18491731
194046_s_at
A_12_P100283
CE25678
CE_WBGene00002299_A
CE_WBGene00002299_B
CGZ0056193
CGZ0056194
GO:0003824
GO:0004672
GO:0004713
GO:0005524
GO:0006468
GO:0016740
GO:0036211
GO:0140096
WBGene00002299
ZK1067.1
ZK1067.1c_3206-3265_0.898_13_C
ZK1067.1c_3274-3333_0.910_8_A
ZK1067.1c_3356-3415_0.901_10_B
ZK1067_1P02561
ZK1067_1P03299
ZK1067_1P03634
cea2.p.53844
Participates
as a component of
Plexin-B1:ErbB2 [plasma membrane] (Caenorhabditis elegans)
ERBB2:p-Y-PLXNB1 [plasma membrane] (Caenorhabditis elegans)
Ub-ERBB2:ERBIN:HSP90:CDC37 [plasma membrane] (Caenorhabditis elegans)
Ub-ERBB2:ERBIN:Ub-HSP90:CDC37 [plasma membrane] (Caenorhabditis elegans)
ERBB2:TKIs [plasma membrane] (Caenorhabditis elegans)
ERBB2:trastuzumab [plasma membrane] (Caenorhabditis elegans)
ERBB2:ERBIN:HSP90:CDC37 [plasma membrane] (Caenorhabditis elegans)
EGF:EGFR:ERBB2 [plasma membrane] (Caenorhabditis elegans)
Other forms of this molecule
phospho-p-6Y-EGFR [clathrin-coated endocytic vesicle membrane]
phospho-ERBB4jmAcyt1s80 [mitochondrial matrix]
phospho-ERBB4jmAcyt2s80 [mitochondrial matrix]
phospho-ERBB4jmAcyt1s80 [nucleoplasm]
phospho-ERBB4jmAcyt2s80 [nucleoplasm]
phospho-ERBB4jmAcyt2m80 [plasma membrane]
phospho-ERBB4jmAcyt1m80 [plasma membrane]
phospho-ERBB4jmAcyt2s80 [cytosol]
phospho-p-7Y,Y1112-ERBB2 [plasma membrane]
phospho-p-6Y-EGFR [plasma membrane]
phospho-p-6Y,Y1112-ERBB2 [plasma membrane]
ERBB4 JM-A CYT-2 isoform [plasma membrane]
ERBB4 JM-B CYT-1 isoform [plasma membrane]
ERBB4 JM-A CYT-1 isoform [plasma membrane]
phospho-p-Y1086,Y1101-EGFR [plasma membrane]
EGFR [plasma membrane]
phospho-p-Y877-ERBB2 [plasma membrane]
ERBB3-1 [plasma membrane]
phospho-p-Y877,Y1023,Y1139,Y1196,Y1221,Y1222-ERBB2 [plasma membrane]
phospho-p-Y1016,Y1069,Y1092,Y1110,Y1197-EGFR [plasma membrane]
phospho-p-Y1023,Y1139,Y1196,Y1221,Y1222-ERBB2 [plasma membrane]
phospho-p-Y877,Y1023,Y1139,Y1221,Y1222-ERBB2 [plasma membrane]
phospho-p-Y1023,Y1139,Y1221,Y1222-ERBB2 [plasma membrane]
phospho-ERBB4jmAcyt1s80 [cytosol]
Inferred From
ERBB2 [plasma membrane]
(Homo sapiens)
Cross References
RefSeq
NP_495962.2
PRO
P24348
PDB
5WNO
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P90976 P90976
0.646
3
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