Reactome | npr-18 [plasma membrane]

npr-18 [plasma membrane]

Stable Identifier

R-CEL-416895-4

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

plasma membrane

Synonyms

PTGDR2, Q09502

Locations in the PathwayBrowser

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Signal Transduction (Caenorhabditis elegans)

- Signaling by GPCR (Caenorhabditis elegans)
  - GPCR downstream signalling (Caenorhabditis elegans)
    - G alpha (i) signalling events (Caenorhabditis elegans)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Caenorhabditis elegans)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Caenorhabditis elegans)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Caenorhabditis elegans)
        
        PTGDR2:PGD2 [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of PTGDR2 [plasma membrane] (Caenorhabditis elegans)
        
        npr-18 [plasma membrane] (Caenorhabditis elegans)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Caenorhabditis elegans)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Caenorhabditis elegans)
        
        PTGDR2:PGD2 [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of PTGDR2 [plasma membrane] (Caenorhabditis elegans)
        
        npr-18 [plasma membrane] (Caenorhabditis elegans)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Caenorhabditis elegans)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Caenorhabditis elegans)
        
        PTGDR2:PGD2 [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of PTGDR2 [plasma membrane] (Caenorhabditis elegans)
        
        npr-18 [plasma membrane] (Caenorhabditis elegans)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Caenorhabditis elegans)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Caenorhabditis elegans)
        
        PTGDR2:PGD2 [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of PTGDR2 [plasma membrane] (Caenorhabditis elegans)
        
        npr-18 [plasma membrane] (Caenorhabditis elegans)
      - The Ligand:GPCR:Gi complex dissociates (Caenorhabditis elegans)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Caenorhabditis elegans)
        
        PTGDR2:PGD2 [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of PTGDR2 [plasma membrane] (Caenorhabditis elegans)
        
        npr-18 [plasma membrane] (Caenorhabditis elegans)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Caenorhabditis elegans)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Caenorhabditis elegans)
        
        PTGDR2:PGD2 [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of PTGDR2 [plasma membrane] (Caenorhabditis elegans)
        
        npr-18 [plasma membrane] (Caenorhabditis elegans)
  - GPCR ligand binding (Caenorhabditis elegans)
    - Class A/1 (Rhodopsin-like receptors) (Caenorhabditis elegans)
      - Eicosanoid ligand-binding receptors (Caenorhabditis elegans)
        
        Prostanoid ligand receptors (Caenorhabditis elegans)
        
        DP2 receptor can bind PGD2 (Caenorhabditis elegans)
        
        Homologues of PTGDR2 [plasma membrane] (Caenorhabditis elegans)
        
        npr-18 [plasma membrane] (Caenorhabditis elegans)
        
        PTGDR2:PGD2 [plasma membrane] (Caenorhabditis elegans)
        
        Homologues of PTGDR2 [plasma membrane] (Caenorhabditis elegans)
        
        npr-18 [plasma membrane] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:Q09502

Gene Names

npr-18

Reference Genes

BioGPS Gene:183408 npr-18

ENSEMBL:WBGene00008065

Monarch:183408 npr-18

NCBI Gene:183408 npr-18

UCSC:Q09502 npr-18

Wormbase:WBGene00008065

Reference Transcript

Participates

as a member of

Homologues of PTGDR2 [plasma membrane] (Caenorhabditis elegans)

Other forms of this molecule

npr-18 [ciliary membrane]

npr-18 [plasma membrane]

Inferred From

PTGDR2 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_001257085.1, NP_001257088.1, NP_001257083.1, NP_001257087.1

PRO

Q09502