Reactome | KSR2 [cytosol]

KSR2 [cytosol]

Stable Identifier

R-CEL-5672589-2

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

cytosol

Synonyms

G5EFD2

Locations in the PathwayBrowser

Expand all

Signal Transduction (Caenorhabditis elegans)

- MAPK family signaling cascades (Caenorhabditis elegans)
  - MAPK1/MAPK3 signaling (Caenorhabditis elegans)
    - RAF/MAP kinase cascade (Caenorhabditis elegans)
      - MAP2K and MAPK activation (Caenorhabditis elegans)
        
        Dissociation of RAS:RAF complex (Caenorhabditis elegans)
        
        RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
        
        Homologues of KSR2 [cytosol] (Caenorhabditis elegans)
        
        KSR2 [cytosol] (Caenorhabditis elegans)
        
        activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Caenorhabditis elegans)
        
        RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
        
        Homologues of KSR2 [cytosol] (Caenorhabditis elegans)
        
        KSR2 [cytosol] (Caenorhabditis elegans)
        
        Dual mechanism MAP2K inhibitors bind MAP2Ks (Caenorhabditis elegans)
        
        activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Caenorhabditis elegans)
        
        RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
        
        Homologues of KSR2 [cytosol] (Caenorhabditis elegans)
        
        KSR2 [cytosol] (Caenorhabditis elegans)
        
        activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Caenorhabditis elegans)
        
        activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Caenorhabditis elegans)
        
        RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
        
        Homologues of KSR2 [cytosol] (Caenorhabditis elegans)
        
        KSR2 [cytosol] (Caenorhabditis elegans)
        
        Dual mechanism MAPK inhibitors bind MAPKs (Caenorhabditis elegans)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Caenorhabditis elegans)
        
        RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
        
        Homologues of KSR2 [cytosol] (Caenorhabditis elegans)
        
        KSR2 [cytosol] (Caenorhabditis elegans)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Caenorhabditis elegans)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Caenorhabditis elegans)
        
        RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
        
        Homologues of KSR2 [cytosol] (Caenorhabditis elegans)
        
        KSR2 [cytosol] (Caenorhabditis elegans)
        
        MAP2Ks and MAPKs bind to the activated RAF complex (Caenorhabditis elegans)
        
        RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
        
        Homologues of KSR2 [cytosol] (Caenorhabditis elegans)
        
        KSR2 [cytosol] (Caenorhabditis elegans)
        
        activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Caenorhabditis elegans)
        
        RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
        
        Homologues of KSR2 [cytosol] (Caenorhabditis elegans)
        
        KSR2 [cytosol] (Caenorhabditis elegans)
        
        MAP2Ks phosphorylate MAPKs (Caenorhabditis elegans)
        
        activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Caenorhabditis elegans)
        
        activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Caenorhabditis elegans)
        
        RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
        
        Homologues of KSR2 [cytosol] (Caenorhabditis elegans)
        
        KSR2 [cytosol] (Caenorhabditis elegans)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Caenorhabditis elegans)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Caenorhabditis elegans)
        
        RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
        
        Homologues of KSR2 [cytosol] (Caenorhabditis elegans)
        
        KSR2 [cytosol] (Caenorhabditis elegans)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Caenorhabditis elegans)
        
        RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
        
        Homologues of KSR2 [cytosol] (Caenorhabditis elegans)
        
        KSR2 [cytosol] (Caenorhabditis elegans)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Caenorhabditis elegans)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Caenorhabditis elegans)
        
        RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
        
        Homologues of KSR2 [cytosol] (Caenorhabditis elegans)
        
        KSR2 [cytosol] (Caenorhabditis elegans)
        
        activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Caenorhabditis elegans)
        
        RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
        
        Homologues of KSR2 [cytosol] (Caenorhabditis elegans)
        
        KSR2 [cytosol] (Caenorhabditis elegans)
        
        RAF phosphorylates MAP2K dimer (Caenorhabditis elegans)
        
        activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Caenorhabditis elegans)
        
        RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
        
        Homologues of KSR2 [cytosol] (Caenorhabditis elegans)
        
        KSR2 [cytosol] (Caenorhabditis elegans)
        
        activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Caenorhabditis elegans)
        
        activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Caenorhabditis elegans)
        
        RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
        
        Homologues of KSR2 [cytosol] (Caenorhabditis elegans)
        
        KSR2 [cytosol] (Caenorhabditis elegans)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Caenorhabditis elegans)
        
        RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
        
        Homologues of KSR2 [cytosol] (Caenorhabditis elegans)
        
        KSR2 [cytosol] (Caenorhabditis elegans)
        
        Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks (Caenorhabditis elegans)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Caenorhabditis elegans)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Caenorhabditis elegans)
        
        RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
        
        Homologues of KSR2 [cytosol] (Caenorhabditis elegans)
        
        KSR2 [cytosol] (Caenorhabditis elegans)
        
        activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Caenorhabditis elegans)
        
        RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
        
        Homologues of KSR2 [cytosol] (Caenorhabditis elegans)
        
        KSR2 [cytosol] (Caenorhabditis elegans)
        
        Single mechanism MAPK inhibitors bind phosphorylated MAPK (Caenorhabditis elegans)
        
        activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Caenorhabditis elegans)
        
        RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
        
        Homologues of KSR2 [cytosol] (Caenorhabditis elegans)
        
        KSR2 [cytosol] (Caenorhabditis elegans)
        
        activated RAF:scaffold:p-2S MAP2K:p-2T MAPK:single mechanism MAPK inhibitors [plasma membrane] (Caenorhabditis elegans)
        
        activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Caenorhabditis elegans)
        
        RAF/MAPK scaffolds [cytosol] (Caenorhabditis elegans)
        
        Homologues of KSR2 [cytosol] (Caenorhabditis elegans)
        
        KSR2 [cytosol] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:G5EFD2

Reference Genes

BioGPS Gene:181082

ENSEMBL:WBGene00002239

Monarch:181082

NCBI Gene:181082

Wormbase:WBGene00002239

Reference Transcript

RefSeq:NM_076995.6

Other Identifiers

175608_at

181082

18607910

188070_s_at

A_12_P115595

CE25854

CE_WBGene00002239_A

CE_WBGene00002239_B

CGZ0015841

CGZ0015842

F13B9.5

F13B9.5_1947-2006_0.926_9_C

F13B9.5_2215-2274_0.943_5_B

F13B9.5_2289-2348_0.956_1_A

F13B9_5P01001

F13B9_5P01652

F13B9_5P02054

GO:0003824

GO:0004672

GO:0005524

GO:0006468

GO:0016740

GO:0036211

GO:0140096

WBGene00002239

cea2.c.43384

Participates

as a member of

Homologues of KSR2 [cytosol] (Caenorhabditis elegans)

Other forms of this molecule

phospho-p-S311,S406 KSR1 [cytosol]

KSR1 [cytosol]

phospho-p-S311 KSR1 [cytosol]

phospho-p-S311,Y602 KSR1 [plasma membrane]

phospho-p-S311,Y602 KSR1 [cytosol]

Inferred From

KSR2 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_509396.1

PRO

G5EFD2

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