Reactome | EXO1,DNA2:BLM,WRN [nucleoplasm]

EXO1,DNA2:BLM,WRN [nucleoplasm]

Stable Identifier

R-CEL-5685980

Type

Set [DefinedSet]

Species

Caenorhabditis elegans

Compartment

nucleoplasm

Locations in the PathwayBrowser

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DNA Repair (Caenorhabditis elegans)

- DNA Double-Strand Break Repair (Caenorhabditis elegans)
  - Homology Directed Repair (Caenorhabditis elegans)
    - HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) (Caenorhabditis elegans)
      - Processing of DNA double-strand break ends (Caenorhabditis elegans)
        
        ATR phosphorylates RPA2 (Caenorhabditis elegans)
        
        ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Caenorhabditis elegans)
        
        ATR:ATRIP:RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Caenorhabditis elegans)
        
        RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Caenorhabditis elegans)
        
        3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1 [nucleoplasm] (Caenorhabditis elegans)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Caenorhabditis elegans)
        
        ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Caenorhabditis elegans)
        
        EXO1,DNA2:BLM,WRN [nucleoplasm] (Caenorhabditis elegans)

Participants

members

Participates

as a component of

Inferred From

EXO1,DNA2:BLM,WRN [nucleoplasm] (Homo sapiens)

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