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srp-8 [endoplasmic reticulum lumen]
Stable Identifier
R-CEL-5689435-8
Type
Protein [EntityWithAccessionedSequence]
Species
Caenorhabditis elegans
Compartment
endoplasmic reticulum lumen
Synonyms
(Glc)3(GlcNAc)2(Man)9-SERPINA1, Q19651
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Caenorhabditis elegans)
Post-translational protein modification (Caenorhabditis elegans)
Asparagine N-linked glycosylation (Caenorhabditis elegans)
Transport to the Golgi and subsequent modification (Caenorhabditis elegans)
ER to Golgi Anterograde Transport (Caenorhabditis elegans)
COPII-mediated vesicle transport (Caenorhabditis elegans)
Inner coat assembly and cargo binding (Caenorhabditis elegans)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
COPII cargo:receptors [endoplasmic reticulum membrane] (Caenorhabditis elegans)
LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Caenorhabditis elegans)
glycosylated LMAN cargo [endoplasmic reticulum lumen] (Caenorhabditis elegans)
Homologues of (Glc)3(GlcNAc)2(Man)9-SERPINA1 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
srp-8 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
COPII cargo:receptors [endoplasmic reticulum membrane] (Caenorhabditis elegans)
LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Caenorhabditis elegans)
glycosylated LMAN cargo [endoplasmic reticulum lumen] (Caenorhabditis elegans)
Homologues of (Glc)3(GlcNAc)2(Man)9-SERPINA1 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
srp-8 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
Loss of SAR1B GTPase (Caenorhabditis elegans)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
COPII cargo:receptors [endoplasmic reticulum membrane] (Caenorhabditis elegans)
LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Caenorhabditis elegans)
glycosylated LMAN cargo [endoplasmic reticulum lumen] (Caenorhabditis elegans)
Homologues of (Glc)3(GlcNAc)2(Man)9-SERPINA1 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
srp-8 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
COPII cargo:receptors [endoplasmic reticulum membrane] (Caenorhabditis elegans)
LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Caenorhabditis elegans)
glycosylated LMAN cargo [endoplasmic reticulum lumen] (Caenorhabditis elegans)
Homologues of (Glc)3(GlcNAc)2(Man)9-SERPINA1 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
srp-8 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
SEC16 complex binds SAR1B:GTP:SEC23:SEC24 (Caenorhabditis elegans)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
COPII cargo:receptors [endoplasmic reticulum membrane] (Caenorhabditis elegans)
LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Caenorhabditis elegans)
glycosylated LMAN cargo [endoplasmic reticulum lumen] (Caenorhabditis elegans)
Homologues of (Glc)3(GlcNAc)2(Man)9-SERPINA1 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
srp-8 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Caenorhabditis elegans)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
COPII cargo:receptors [endoplasmic reticulum membrane] (Caenorhabditis elegans)
LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Caenorhabditis elegans)
glycosylated LMAN cargo [endoplasmic reticulum lumen] (Caenorhabditis elegans)
Homologues of (Glc)3(GlcNAc)2(Man)9-SERPINA1 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
srp-8 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
Vesicle budding (Caenorhabditis elegans)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Caenorhabditis elegans)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Caenorhabditis elegans)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
COPII cargo:receptors [endoplasmic reticulum membrane] (Caenorhabditis elegans)
LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Caenorhabditis elegans)
glycosylated LMAN cargo [endoplasmic reticulum lumen] (Caenorhabditis elegans)
Homologues of (Glc)3(GlcNAc)2(Man)9-SERPINA1 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
srp-8 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
Cargo concentration in the ER (Caenorhabditis elegans)
Inner coat assembly and cargo binding (Caenorhabditis elegans)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
COPII cargo:receptors [endoplasmic reticulum membrane] (Caenorhabditis elegans)
LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Caenorhabditis elegans)
glycosylated LMAN cargo [endoplasmic reticulum lumen] (Caenorhabditis elegans)
Homologues of (Glc)3(GlcNAc)2(Man)9-SERPINA1 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
srp-8 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
COPII cargo:receptors [endoplasmic reticulum membrane] (Caenorhabditis elegans)
LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Caenorhabditis elegans)
glycosylated LMAN cargo [endoplasmic reticulum lumen] (Caenorhabditis elegans)
Homologues of (Glc)3(GlcNAc)2(Man)9-SERPINA1 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
srp-8 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
LMAN family proteins bind glycosylated cargo (Caenorhabditis elegans)
LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Caenorhabditis elegans)
glycosylated LMAN cargo [endoplasmic reticulum lumen] (Caenorhabditis elegans)
Homologues of (Glc)3(GlcNAc)2(Man)9-SERPINA1 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
srp-8 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
glycosylated LMAN cargo [endoplasmic reticulum lumen] (Caenorhabditis elegans)
Homologues of (Glc)3(GlcNAc)2(Man)9-SERPINA1 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
srp-8 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
Vesicle-mediated transport (Caenorhabditis elegans)
Membrane Trafficking (Caenorhabditis elegans)
ER to Golgi Anterograde Transport (Caenorhabditis elegans)
COPII-mediated vesicle transport (Caenorhabditis elegans)
Inner coat assembly and cargo binding (Caenorhabditis elegans)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
COPII cargo:receptors [endoplasmic reticulum membrane] (Caenorhabditis elegans)
LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Caenorhabditis elegans)
glycosylated LMAN cargo [endoplasmic reticulum lumen] (Caenorhabditis elegans)
Homologues of (Glc)3(GlcNAc)2(Man)9-SERPINA1 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
srp-8 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
COPII cargo:receptors [endoplasmic reticulum membrane] (Caenorhabditis elegans)
LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Caenorhabditis elegans)
glycosylated LMAN cargo [endoplasmic reticulum lumen] (Caenorhabditis elegans)
Homologues of (Glc)3(GlcNAc)2(Man)9-SERPINA1 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
srp-8 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
Loss of SAR1B GTPase (Caenorhabditis elegans)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
COPII cargo:receptors [endoplasmic reticulum membrane] (Caenorhabditis elegans)
LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Caenorhabditis elegans)
glycosylated LMAN cargo [endoplasmic reticulum lumen] (Caenorhabditis elegans)
Homologues of (Glc)3(GlcNAc)2(Man)9-SERPINA1 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
srp-8 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
COPII cargo:receptors [endoplasmic reticulum membrane] (Caenorhabditis elegans)
LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Caenorhabditis elegans)
glycosylated LMAN cargo [endoplasmic reticulum lumen] (Caenorhabditis elegans)
Homologues of (Glc)3(GlcNAc)2(Man)9-SERPINA1 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
srp-8 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
SEC16 complex binds SAR1B:GTP:SEC23:SEC24 (Caenorhabditis elegans)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
COPII cargo:receptors [endoplasmic reticulum membrane] (Caenorhabditis elegans)
LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Caenorhabditis elegans)
glycosylated LMAN cargo [endoplasmic reticulum lumen] (Caenorhabditis elegans)
Homologues of (Glc)3(GlcNAc)2(Man)9-SERPINA1 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
srp-8 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Caenorhabditis elegans)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
COPII cargo:receptors [endoplasmic reticulum membrane] (Caenorhabditis elegans)
LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Caenorhabditis elegans)
glycosylated LMAN cargo [endoplasmic reticulum lumen] (Caenorhabditis elegans)
Homologues of (Glc)3(GlcNAc)2(Man)9-SERPINA1 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
srp-8 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
Vesicle budding (Caenorhabditis elegans)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer:SEC13:SEC31:SEC23IP:v-SNARES [endoplasmic reticulum membrane] (Caenorhabditis elegans)
COPII cargo:receptors:SAR1B:GTP:SEC23:SEC24:SEC16A:SEC16B:TFG hexamer [endoplasmic reticulum membrane] (Caenorhabditis elegans)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
COPII cargo:receptors [endoplasmic reticulum membrane] (Caenorhabditis elegans)
LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Caenorhabditis elegans)
glycosylated LMAN cargo [endoplasmic reticulum lumen] (Caenorhabditis elegans)
Homologues of (Glc)3(GlcNAc)2(Man)9-SERPINA1 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
srp-8 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
Cargo concentration in the ER (Caenorhabditis elegans)
Inner coat assembly and cargo binding (Caenorhabditis elegans)
COPII cargo receptors:SAR1B:GTP:SEC23:SEC24 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
COPII cargo:receptors [endoplasmic reticulum membrane] (Caenorhabditis elegans)
LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Caenorhabditis elegans)
glycosylated LMAN cargo [endoplasmic reticulum lumen] (Caenorhabditis elegans)
Homologues of (Glc)3(GlcNAc)2(Man)9-SERPINA1 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
srp-8 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
COPII cargo:receptors [endoplasmic reticulum membrane] (Caenorhabditis elegans)
LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Caenorhabditis elegans)
glycosylated LMAN cargo [endoplasmic reticulum lumen] (Caenorhabditis elegans)
Homologues of (Glc)3(GlcNAc)2(Man)9-SERPINA1 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
srp-8 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
LMAN family proteins bind glycosylated cargo (Caenorhabditis elegans)
LMAN receptor:glycosylated cargo [endoplasmic reticulum membrane] (Caenorhabditis elegans)
glycosylated LMAN cargo [endoplasmic reticulum lumen] (Caenorhabditis elegans)
Homologues of (Glc)3(GlcNAc)2(Man)9-SERPINA1 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
srp-8 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
glycosylated LMAN cargo [endoplasmic reticulum lumen] (Caenorhabditis elegans)
Homologues of (Glc)3(GlcNAc)2(Man)9-SERPINA1 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
srp-8 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
External Reference Information
External Reference
UniProt:Q19651
Gene Names
srp-8
Reference Genes
BioGPS Gene:191960 srp-8
CTD Gene:191960 srp-8
ENSEMBL:WBGene00005649
Monarch:191960 srp-8
NCBI Gene:191960 srp-8
UCSC:Q19651 srp-8
Wormbase:WBGene00005649
Reference Transcript
RefSeq:NM_001322578.1 srp-8
Other Identifiers
18567534
191960
192846_at
A_12_P110672
A_12_P156695
A_12_P156696
A_12_P156697
CE07108
CE_WBGene00005649_A
CGZ0017188
F20D6.3
F20D6.3_708-767_0.923_1_A
F20D6_3P00109
F20D6_3P00553
F20D6_3P00793
GO:0004867
GO:0005576
GO:0005615
GO:0098772
WBGene00005649
cea2.i.37089
Participates
as a member of
Homologues of (Glc)3(GlcNAc)2(Man)9-SERPINA1 [endoplasmic reticulum lumen] (Caenorhabditis elegans)
Other forms of this molecule
srp-8 [extracellular region]
srp-8 [extracellular region]
srp-8 [extracellular region]
srp-8 [extracellular region]
srp-8 [extracellular region]
srp-8 [extracellular region]
srp-8 [extracellular region]
srp-8 [extracellular region]
srp-8 [extracellular region]
srp-8 [extracellular region]
srp-8 [endoplasmic reticulum lumen]
srp-8 [endoplasmic reticulum lumen]
srp-8 [endoplasmic reticulum lumen]
phospho-srp-8 [endoplasmic reticulum lumen]
phospho-srp-8 [endoplasmic reticulum lumen]
phospho-srp-8 [endoplasmic reticulum lumen]
srp-8 [COPII-coated ER to Golgi transport vesicle]
srp-8 [endoplasmic reticulum-Golgi intermediate compartment membrane]
srp-8 [ficolin-1-rich granule lumen]
srp-8 [extracellular region]
srp-8 [secretory granule lumen]
srp-8 [extracellular region]
srp-8 [ficolin-1-rich granule membrane]
srp-8 [plasma membrane]
srp-8 [azurophil granule lumen]
srp-8 [azurophil granule lumen]
srp-8 [extracellular region]
srp-8 [lysosomal lumen]
srp-8 [endoplasmic reticulum lumen]
srp-8 [extracellular region]
srp-8 [plasma membrane]
srp-8 [extracellular region]
srp-8 [platelet dense granule lumen]
srp-8 [extracellular region]
srp-8 [platelet alpha granule lumen]
srp-8 [platelet alpha granule lumen]
srp-8 [platelet alpha granule lumen]
srp-8 [platelet alpha granule lumen]
Inferred From
(Glc)3(GlcNAc)2(Man)9-SERPINA1 [endoplasmic reticulum lumen]
(Homo sapiens)
Modified Residues
Name
N4-(N-acetylamino)glucosyl-L-asparagine (N-{alpha-Glc-(1->2)-alpha-Glc-(1->3)-alpha-Glc-(1->3)-alpha-Man-(1->2)-alpha-Man-(1->2)-alpha-Man-(1->3)-(alpha-Man-(1->2)-alpha-Man-(1->3)-(alpha-Man-(1->2)-alpha-Man-(1->6))-alpha-Man-(1->6))-beta-Man-(1->4)-beta-GlcNAc-(1->4)-beta-GlcNAc}-L-Asn residue (ChEBI:59084)) at unknown position
Modification
N-{alpha-Glc-(1->2)-alpha-Glc-(1->3)-alpha-Glc-(1->3)-alpha-Man-(1->2)-alpha-Man-(1->2)-alpha-Man-(1->3)-(alpha-Man-(1->2)-alpha-Man-(1->3)-(alpha-Man-(1->2)-alpha-Man-(1->6))-alpha-Man-(1->6))-beta-Man-(1->4)-beta-GlcNAc-(1->4)-beta-GlcNAc}-yl group (ChEBI:59084)
PsiMod Name
N4-(N-acetylamino)glucosyl-L-asparagine
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.
Cross References
RefSeq
NP_001309497.1
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