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AKT1 [cytosol]
Stable Identifier
R-CEL-58252
Type
Protein [EntityWithAccessionedSequence]
Species
Caenorhabditis elegans
Compartment
cytosol
Synonyms
Q17941
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Caenorhabditis elegans)
Cellular responses to stress (Caenorhabditis elegans)
Mitochondrial unfolded protein response (UPRmt) (Caenorhabditis elegans)
Phosphorylation of AKT1 on serine-473 in response to reactive oxygen species (Caenorhabditis elegans)
Homologues of AKT1 [cytosol] (Caenorhabditis elegans)
AKT1 [cytosol] (Caenorhabditis elegans)
Immune System (Caenorhabditis elegans)
Adaptive Immune System (Caenorhabditis elegans)
Regulation of T cell activation by CD28 family (Caenorhabditis elegans)
Co-inhibition by CTLA4 (Caenorhabditis elegans)
Dephosphorylation of AKT by PP2A (Caenorhabditis elegans)
AKT [cytosol] (Caenorhabditis elegans)
Homologues of AKT1 [cytosol] (Caenorhabditis elegans)
AKT1 [cytosol] (Caenorhabditis elegans)
Co-stimulation by CD28 (Caenorhabditis elegans)
CD28 dependent PI3K/Akt signaling (Caenorhabditis elegans)
PIP3 recruits AKT to the membrane (Caenorhabditis elegans)
AKT [cytosol] (Caenorhabditis elegans)
Homologues of AKT1 [cytosol] (Caenorhabditis elegans)
AKT1 [cytosol] (Caenorhabditis elegans)
Signal Transduction (Caenorhabditis elegans)
Intracellular signaling by second messengers (Caenorhabditis elegans)
PIP3 activates AKT signaling (Caenorhabditis elegans)
Negative regulation of the PI3K/AKT network (Caenorhabditis elegans)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Caenorhabditis elegans)
AKT1 dephosphorylation by PP2A-B56-beta,gamma (Caenorhabditis elegans)
Homologues of AKT1 [cytosol] (Caenorhabditis elegans)
AKT1 [cytosol] (Caenorhabditis elegans)
PIP3 recruits AKT to the membrane (Caenorhabditis elegans)
AKT [cytosol] (Caenorhabditis elegans)
Homologues of AKT1 [cytosol] (Caenorhabditis elegans)
AKT1 [cytosol] (Caenorhabditis elegans)
Signaling by GPCR (Caenorhabditis elegans)
GPCR downstream signalling (Caenorhabditis elegans)
G-protein beta:gamma signalling (Caenorhabditis elegans)
G beta:gamma signalling through PI3Kgamma (Caenorhabditis elegans)
PIP3 recruits PDK1 and AKT to the membrane (Caenorhabditis elegans)
AKT [cytosol] (Caenorhabditis elegans)
Homologues of AKT1 [cytosol] (Caenorhabditis elegans)
AKT1 [cytosol] (Caenorhabditis elegans)
Signaling by Non-Receptor Tyrosine Kinases (Caenorhabditis elegans)
Signaling by PTK6 (Caenorhabditis elegans)
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 (Caenorhabditis elegans)
PTK6 binds AKT1 (Caenorhabditis elegans)
Homologues of AKT1 [cytosol] (Caenorhabditis elegans)
AKT1 [cytosol] (Caenorhabditis elegans)
p-Y342-PTK6:AKT1 [cytosol] (Caenorhabditis elegans)
Homologues of AKT1 [cytosol] (Caenorhabditis elegans)
AKT1 [cytosol] (Caenorhabditis elegans)
PTK6 phosphorylates AKT1 (Caenorhabditis elegans)
p-Y342-PTK6:AKT1 [cytosol] (Caenorhabditis elegans)
Homologues of AKT1 [cytosol] (Caenorhabditis elegans)
AKT1 [cytosol] (Caenorhabditis elegans)
External Reference Information
External Reference
UniProt:Q17941
Reference Genes
BioGPS Gene:179424
CTD Gene:179424
ENSEMBL:WBGene00000102
KEGG:cel:CELE_C12D8.10
Monarch:179424
NCBI Gene:179424
UCSC:Q17941
Wormbase:WBGene00000102
Reference Transcript
RefSeq:NM_001028475.2
RefSeq:NM_001028474.4
RefSeq:NM_001028476.3
Other Identifiers
175808_s_at
179424
18562897
194058_s_at
A_12_P115079
A_12_P157140
C12D8.10
C12D8.10a
C12D8.10b
C12D8.10b_1278-1337_0.926_2_B
C12D8.10b_1362-1421_0.912_5_C
C12D8.10b_1511-1570_0.956_1_A
C12D8_10aP00806
C12D8_10aP00853
C12D8_10aP00902
C12D8_10bP00791
C12D8_10bP00855
C12D8_10bP00871
C12D8_10cP00228
C12D8_10cP00432
C12D8_10cP00495
CE05274
CE15612
CE_WBGene00000102_A
CE_WBGene00000102_B
CE_WBGene00000102_C
CGZ0004336
CGZ0004337
GO:0002376
GO:0003824
GO:0004672
GO:0004674
GO:0005515
GO:0005516
GO:0005524
GO:0005547
GO:0006468
GO:0006935
GO:0007635
GO:0008286
GO:0008289
GO:0008340
GO:0008582
GO:0009898
GO:0010468
GO:0016740
GO:0030424
GO:0030425
GO:0035556
GO:0042771
GO:0043025
GO:0045087
GO:0046872
GO:0098542
GO:0106310
GO:0140096
GO:1902074
GO:1902911
WBGene00000102
cea2.d.00613
cea2.d.12476
Participates
as a member of
Homologues of AKT1 [cytosol] (Caenorhabditis elegans)
Other forms of this molecule
phospho-p-T309,S474-AKT2 [nucleoplasm]
phospho-p-T305,S472-AKT3 [nucleoplasm]
phospho-p-T308,S473-AKT1 [nucleoplasm]
phospho-p-T305,S472-AKT3 [cytosol]
phospho-p-T309,S474-AKT2 [cytosol]
phospho-p-T308,S473-AKT1 [cytosol]
phospho-p-S474-AKT2 [plasma membrane]
phospho-p-S472-AKT3 [plasma membrane]
phospho-p-S473-AKT1 [plasma membrane]
AKT2 [plasma membrane]
AKT3 [plasma membrane]
AKT1 [plasma membrane]
AKT2 [cytosol]
AKT3 [cytosol]
phospho-p-T309-AKT2 [cytosol]
phospho-p-T305-AKT3 [cytosol]
phospho-p-T308-AKT1 [cytosol]
phospho-p-Y315,Y326-AKT1 [cytosol]
phospho-p-T308,S473-AKT1 [plasma membrane]
phospho-p-S473-AKT1 [cytosol]
Inferred From
AKT1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001023647.1
,
NP_001023645.1
,
NP_001023646.1
ENSEMBL
C12D8.10a.1
PRO
Q17941
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O16850
19
daf-16 [nucleoplasm]
(R-CEL-199300)
daf-16 [nucleoplasm]
(R-CEL-5690183)
daf-16 [nucleoplasm]
(R-CEL-199305)
daf-16 [nucleoplasm]
(R-CEL-9614396)
phospho-daf-16 [nucleoplasm]
(R-CEL-9614995)
phospho-daf-16 [nucleoplasm]
(R-CEL-199314)
phospho-daf-16 [nucleoplasm]
(R-CEL-199306)
phospho-daf-16 [nucleoplasm]
(R-CEL-199289)
phospho-daf-16 [cytosol]
(R-CEL-9614413)
phospho-daf-16 [cytosol]
(R-CEL-211158)
phospho-daf-16 [cytosol]
(R-CEL-9614415)
daf-16 [nucleoplasm]
(R-CEL-9620514)
daf-16 [mitochondrial matrix]
(R-CEL-9841849)
daf-16 [mitochondrial matrix]
(R-CEL-9841824)
daf-16 [cytosol]
(R-CEL-5687032)
daf-16 [nucleoplasm]
(R-CEL-6782501)
phospho-daf-16 [cytosol]
(R-CEL-5687014)
phospho-daf-16 [nucleoplasm]
(R-CEL-5687010)
phospho-daf-16 [nucleoplasm]
(R-CEL-5692651)
0.676
3
UniProt:Q2PJ68
6
SGK3 [cytosol]
(R-CEL-2682351)
SGK2 [cytosol]
(R-CEL-2682364)
SGK1 [cytosol]
(R-CEL-2682356)
phospho-p-S422-SGK1 [cytosol]
(R-CEL-6795313)
phospho-p-T256,S422-SGK1 [cytosol]
(R-CEL-6795449)
phospho-p-T256,S422-SGK1 [nucleoplasm]
(R-CEL-9612512)
0.567
3
UniProt:Q9XTG7
15
phospho-p-S473-AKT1 [cytosol]
(R-CEL-9841264-2)
phospho-p-T308,S473-AKT1 [plasma membrane]
(R-CEL-199430-2)
phospho-p-Y315,Y326-AKT1 [cytosol]
(R-CEL-8848757-2)
phospho-p-T308-AKT1 [cytosol]
(R-CEL-198634-2)
phospho-p-T309-AKT2 [cytosol]
(R-CEL-202066-2)
AKT1 [cytosol]
(R-CEL-58252-2)
AKT2 [cytosol]
(R-CEL-49859-2)
AKT1 [plasma membrane]
(R-CEL-199416-2)
AKT2 [plasma membrane]
(R-CEL-202053-2)
phospho-p-S473-AKT1 [plasma membrane]
(R-CEL-377265-2)
phospho-p-S474-AKT2 [plasma membrane]
(R-CEL-2317312-2)
phospho-p-T308,S473-AKT1 [cytosol]
(R-CEL-198356-2)
phospho-p-T309,S474-AKT2 [cytosol]
(R-CEL-202062-2)
phospho-p-T308,S473-AKT1 [nucleoplasm]
(R-CEL-198357-2)
phospho-p-T309,S474-AKT2 [nucleoplasm]
(R-CEL-202087-2)
0.508
2
UniProt:O18178
4
phospho-pptr-1 [cytosol]
(R-CEL-9836658)
pptr-1 [cytosol]
(R-CEL-1638770)
pptr-1 [cytosol]
(R-CEL-196235)
pptr-1 [cytosol]
(R-CEL-535469)
0.463
3
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