Reactome | ints-5 [nucleoplasm]

ints-5 [nucleoplasm]

Stable Identifier

R-CEL-6807418

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

nucleoplasm

Synonyms

INTS5, Q9U267

Locations in the PathwayBrowser

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Gene expression (Transcription) (Caenorhabditis elegans)

- RNA Polymerase II Transcription (Caenorhabditis elegans)
  - RNA polymerase II transcribes snRNA genes (Caenorhabditis elegans)
    - CBCAP complex binds 7-methylguanosine cap of snRNA (Caenorhabditis elegans)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Caenorhabditis elegans)
        
        Integrator [nucleoplasm] (Caenorhabditis elegans)
        
        ints-5 [nucleoplasm] (Caenorhabditis elegans)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Caenorhabditis elegans)
        
        Integrator [nucleoplasm] (Caenorhabditis elegans)
        
        ints-5 [nucleoplasm] (Caenorhabditis elegans)
    - Integrator complex processes the 3' end of snRNA (Caenorhabditis elegans)
      - Integrator [nucleoplasm] (Caenorhabditis elegans)
        
        ints-5 [nucleoplasm] (Caenorhabditis elegans)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Caenorhabditis elegans)
        
        Integrator [nucleoplasm] (Caenorhabditis elegans)
        
        ints-5 [nucleoplasm] (Caenorhabditis elegans)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Caenorhabditis elegans)
        
        Integrator [nucleoplasm] (Caenorhabditis elegans)
        
        ints-5 [nucleoplasm] (Caenorhabditis elegans)
    - Pre-snRNA is elongated and capped with 7-methylguanosine (Caenorhabditis elegans)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Caenorhabditis elegans)
        
        Integrator [nucleoplasm] (Caenorhabditis elegans)
        
        ints-5 [nucleoplasm] (Caenorhabditis elegans)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Caenorhabditis elegans)
        
        Integrator [nucleoplasm] (Caenorhabditis elegans)
        
        ints-5 [nucleoplasm] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:Q9U267

Gene Names

ints-5

Reference Genes

BioGPS Gene:180207 ints-5

ENSEMBL:WBGene00013075

KEGG:cel:CELE_Y51A2D.7 ints-5

Monarch:180207 ints-5

NCBI Entrez Gene:180207 ints-5

UCSC:Q9U267 ints-5

Wormbase:WBGene00013075

Wormbase:WBGene00013075 ints-5

Reference Transcript

RefSeq:NM_075224.6 ints-5

Other Identifiers

180207

GO:0016073

GO:0032039

GO:0034472

Participates

as a component of

Integrator [nucleoplasm] (Caenorhabditis elegans)

Inferred From

INTS5 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_507625.2

ENSEMBL

Y51A2D.7b.1, WBGene00013075, Y51A2D.7b.1