Reactome | ints-1 [nucleoplasm]

ints-1 [nucleoplasm]

Stable Identifier

R-CEL-6807446

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

nucleoplasm

Synonyms

INTS1, O01483

Locations in the PathwayBrowser

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Gene expression (Transcription) (Caenorhabditis elegans)

- RNA Polymerase II Transcription (Caenorhabditis elegans)
  - RNA polymerase II transcribes snRNA genes (Caenorhabditis elegans)
    - CBCAP complex binds 7-methylguanosine cap of snRNA (Caenorhabditis elegans)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Caenorhabditis elegans)
        
        Integrator [nucleoplasm] (Caenorhabditis elegans)
        
        ints-1 [nucleoplasm] (Caenorhabditis elegans)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Caenorhabditis elegans)
        
        Integrator [nucleoplasm] (Caenorhabditis elegans)
        
        ints-1 [nucleoplasm] (Caenorhabditis elegans)
    - Integrator complex processes the 3' end of snRNA (Caenorhabditis elegans)
      - Integrator [nucleoplasm] (Caenorhabditis elegans)
        
        ints-1 [nucleoplasm] (Caenorhabditis elegans)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Caenorhabditis elegans)
        
        Integrator [nucleoplasm] (Caenorhabditis elegans)
        
        ints-1 [nucleoplasm] (Caenorhabditis elegans)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Caenorhabditis elegans)
        
        Integrator [nucleoplasm] (Caenorhabditis elegans)
        
        ints-1 [nucleoplasm] (Caenorhabditis elegans)
    - Pre-snRNA is elongated and capped with 7-methylguanosine (Caenorhabditis elegans)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Caenorhabditis elegans)
        
        Integrator [nucleoplasm] (Caenorhabditis elegans)
        
        ints-1 [nucleoplasm] (Caenorhabditis elegans)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Caenorhabditis elegans)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Caenorhabditis elegans)
        
        Integrator [nucleoplasm] (Caenorhabditis elegans)
        
        ints-1 [nucleoplasm] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:O01483

Gene Names

ints-1

Reference Genes

BioGPS Gene:182280 ints-1

ENSEMBL:WBGene00015499

Monarch:182280 ints-1

NCBI Gene:182280 ints-1

UCSC:O01483 ints-1

Wormbase:WBGene00015499

Reference Transcript

RefSeq:NM_059338.2 ints-1

Other Identifiers

182280

183766_at

18451331

A_12_P107504

C06A5.1

C06A5.1_5440-5499_0.935_6_C

C06A5.1_5523-5582_0.939_3_B

C06A5.1_5646-5705_0.935_7_A

C06A5_1P04597

C06A5_1P05385

C06A5_1P05703

CE07948

CE_WBGene00015499_A

CE_WBGene00015499_B

CGZ0002736

GO:0005634

GO:0016073

GO:0032039

GO:0034474

GO:0043226

WBGene00015499

cea2.i.00307

Participates

as a component of

Integrator [nucleoplasm] (Caenorhabditis elegans)

Inferred From

INTS1 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_491739.2

PRO

O01483