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orc-1 [nucleoplasm]
Stable Identifier
R-CEL-68522
Type
Protein [EntityWithAccessionedSequence]
Species
Caenorhabditis elegans
Compartment
nucleoplasm
Synonyms
ORC1, Q9XX17
Locations in the PathwayBrowser
Expand all
Cell Cycle (Caenorhabditis elegans)
Cell Cycle, Mitotic (Caenorhabditis elegans)
Mitotic G1 phase and G1/S transition (Caenorhabditis elegans)
G1/S Transition (Caenorhabditis elegans)
Activation of the pre-replicative complex (Caenorhabditis elegans)
Cdc45 associates with the pre-replicative complex at the origin (Caenorhabditis elegans)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Caenorhabditis elegans)
MCM10:active pre-replicative complex [nucleoplasm] (Caenorhabditis elegans)
active pre-replicative complex [nucleoplasm] (Caenorhabditis elegans)
CDC6:ORC:origin complex [nucleoplasm] (Caenorhabditis elegans)
ORC:origin of replication [nucleoplasm] (Caenorhabditis elegans)
orc-1 [nucleoplasm] (Caenorhabditis elegans)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Caenorhabditis elegans)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Caenorhabditis elegans)
MCM10:active pre-replicative complex [nucleoplasm] (Caenorhabditis elegans)
active pre-replicative complex [nucleoplasm] (Caenorhabditis elegans)
CDC6:ORC:origin complex [nucleoplasm] (Caenorhabditis elegans)
ORC:origin of replication [nucleoplasm] (Caenorhabditis elegans)
orc-1 [nucleoplasm] (Caenorhabditis elegans)
Cdt1 is displaced from the pre-replicative complex (Caenorhabditis elegans)
MCM10:active pre-replicative complex [nucleoplasm] (Caenorhabditis elegans)
active pre-replicative complex [nucleoplasm] (Caenorhabditis elegans)
CDC6:ORC:origin complex [nucleoplasm] (Caenorhabditis elegans)
ORC:origin of replication [nucleoplasm] (Caenorhabditis elegans)
orc-1 [nucleoplasm] (Caenorhabditis elegans)
MCM10:pre-replicative complex [nucleoplasm] (Caenorhabditis elegans)
pre-replicative complex [nucleoplasm] (Caenorhabditis elegans)
CDT1:CDC6:ORC:origin complex [nucleoplasm] (Caenorhabditis elegans)
CDC6:ORC:origin complex [nucleoplasm] (Caenorhabditis elegans)
ORC:origin of replication [nucleoplasm] (Caenorhabditis elegans)
orc-1 [nucleoplasm] (Caenorhabditis elegans)
DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin (Caenorhabditis elegans)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Caenorhabditis elegans)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Caenorhabditis elegans)
MCM10:active pre-replicative complex [nucleoplasm] (Caenorhabditis elegans)
active pre-replicative complex [nucleoplasm] (Caenorhabditis elegans)
CDC6:ORC:origin complex [nucleoplasm] (Caenorhabditis elegans)
ORC:origin of replication [nucleoplasm] (Caenorhabditis elegans)
orc-1 [nucleoplasm] (Caenorhabditis elegans)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Caenorhabditis elegans)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Caenorhabditis elegans)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Caenorhabditis elegans)
MCM10:active pre-replicative complex [nucleoplasm] (Caenorhabditis elegans)
active pre-replicative complex [nucleoplasm] (Caenorhabditis elegans)
CDC6:ORC:origin complex [nucleoplasm] (Caenorhabditis elegans)
ORC:origin of replication [nucleoplasm] (Caenorhabditis elegans)
orc-1 [nucleoplasm] (Caenorhabditis elegans)
DNA polymerase alpha:primase binds at the origin (Caenorhabditis elegans)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Caenorhabditis elegans)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Caenorhabditis elegans)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Caenorhabditis elegans)
MCM10:active pre-replicative complex [nucleoplasm] (Caenorhabditis elegans)
active pre-replicative complex [nucleoplasm] (Caenorhabditis elegans)
CDC6:ORC:origin complex [nucleoplasm] (Caenorhabditis elegans)
ORC:origin of replication [nucleoplasm] (Caenorhabditis elegans)
orc-1 [nucleoplasm] (Caenorhabditis elegans)
DNA polymerase epsilon binds at the origin (Caenorhabditis elegans)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Caenorhabditis elegans)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Caenorhabditis elegans)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Caenorhabditis elegans)
MCM10:active pre-replicative complex [nucleoplasm] (Caenorhabditis elegans)
active pre-replicative complex [nucleoplasm] (Caenorhabditis elegans)
CDC6:ORC:origin complex [nucleoplasm] (Caenorhabditis elegans)
ORC:origin of replication [nucleoplasm] (Caenorhabditis elegans)
orc-1 [nucleoplasm] (Caenorhabditis elegans)
Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7 (Caenorhabditis elegans)
MCM10:pre-replicative complex [nucleoplasm] (Caenorhabditis elegans)
pre-replicative complex [nucleoplasm] (Caenorhabditis elegans)
CDT1:CDC6:ORC:origin complex [nucleoplasm] (Caenorhabditis elegans)
CDC6:ORC:origin complex [nucleoplasm] (Caenorhabditis elegans)
ORC:origin of replication [nucleoplasm] (Caenorhabditis elegans)
orc-1 [nucleoplasm] (Caenorhabditis elegans)
pre-replicative complex [nucleoplasm] (Caenorhabditis elegans)
CDT1:CDC6:ORC:origin complex [nucleoplasm] (Caenorhabditis elegans)
CDC6:ORC:origin complex [nucleoplasm] (Caenorhabditis elegans)
ORC:origin of replication [nucleoplasm] (Caenorhabditis elegans)
orc-1 [nucleoplasm] (Caenorhabditis elegans)
S Phase (Caenorhabditis elegans)
Synthesis of DNA (Caenorhabditis elegans)
Switching of origins to a post-replicative state (Caenorhabditis elegans)
Orc1 removal from chromatin (Caenorhabditis elegans)
Orc1 is phosphorylated by cyclin A/CDK2 (Caenorhabditis elegans)
pre-replicative complex [nucleoplasm] (Caenorhabditis elegans)
CDT1:CDC6:ORC:origin complex [nucleoplasm] (Caenorhabditis elegans)
CDC6:ORC:origin complex [nucleoplasm] (Caenorhabditis elegans)
ORC:origin of replication [nucleoplasm] (Caenorhabditis elegans)
orc-1 [nucleoplasm] (Caenorhabditis elegans)
DNA Replication (Caenorhabditis elegans)
DNA Replication Pre-Initiation (Caenorhabditis elegans)
Activation of the pre-replicative complex (Caenorhabditis elegans)
Cdc45 associates with the pre-replicative complex at the origin (Caenorhabditis elegans)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Caenorhabditis elegans)
MCM10:active pre-replicative complex [nucleoplasm] (Caenorhabditis elegans)
active pre-replicative complex [nucleoplasm] (Caenorhabditis elegans)
CDC6:ORC:origin complex [nucleoplasm] (Caenorhabditis elegans)
ORC:origin of replication [nucleoplasm] (Caenorhabditis elegans)
orc-1 [nucleoplasm] (Caenorhabditis elegans)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Caenorhabditis elegans)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Caenorhabditis elegans)
MCM10:active pre-replicative complex [nucleoplasm] (Caenorhabditis elegans)
active pre-replicative complex [nucleoplasm] (Caenorhabditis elegans)
CDC6:ORC:origin complex [nucleoplasm] (Caenorhabditis elegans)
ORC:origin of replication [nucleoplasm] (Caenorhabditis elegans)
orc-1 [nucleoplasm] (Caenorhabditis elegans)
Cdt1 is displaced from the pre-replicative complex (Caenorhabditis elegans)
MCM10:active pre-replicative complex [nucleoplasm] (Caenorhabditis elegans)
active pre-replicative complex [nucleoplasm] (Caenorhabditis elegans)
CDC6:ORC:origin complex [nucleoplasm] (Caenorhabditis elegans)
ORC:origin of replication [nucleoplasm] (Caenorhabditis elegans)
orc-1 [nucleoplasm] (Caenorhabditis elegans)
MCM10:pre-replicative complex [nucleoplasm] (Caenorhabditis elegans)
pre-replicative complex [nucleoplasm] (Caenorhabditis elegans)
CDT1:CDC6:ORC:origin complex [nucleoplasm] (Caenorhabditis elegans)
CDC6:ORC:origin complex [nucleoplasm] (Caenorhabditis elegans)
ORC:origin of replication [nucleoplasm] (Caenorhabditis elegans)
orc-1 [nucleoplasm] (Caenorhabditis elegans)
DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin (Caenorhabditis elegans)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Caenorhabditis elegans)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Caenorhabditis elegans)
MCM10:active pre-replicative complex [nucleoplasm] (Caenorhabditis elegans)
active pre-replicative complex [nucleoplasm] (Caenorhabditis elegans)
CDC6:ORC:origin complex [nucleoplasm] (Caenorhabditis elegans)
ORC:origin of replication [nucleoplasm] (Caenorhabditis elegans)
orc-1 [nucleoplasm] (Caenorhabditis elegans)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Caenorhabditis elegans)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Caenorhabditis elegans)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Caenorhabditis elegans)
MCM10:active pre-replicative complex [nucleoplasm] (Caenorhabditis elegans)
active pre-replicative complex [nucleoplasm] (Caenorhabditis elegans)
CDC6:ORC:origin complex [nucleoplasm] (Caenorhabditis elegans)
ORC:origin of replication [nucleoplasm] (Caenorhabditis elegans)
orc-1 [nucleoplasm] (Caenorhabditis elegans)
DNA polymerase alpha:primase binds at the origin (Caenorhabditis elegans)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Caenorhabditis elegans)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Caenorhabditis elegans)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Caenorhabditis elegans)
MCM10:active pre-replicative complex [nucleoplasm] (Caenorhabditis elegans)
active pre-replicative complex [nucleoplasm] (Caenorhabditis elegans)
CDC6:ORC:origin complex [nucleoplasm] (Caenorhabditis elegans)
ORC:origin of replication [nucleoplasm] (Caenorhabditis elegans)
orc-1 [nucleoplasm] (Caenorhabditis elegans)
DNA polymerase epsilon binds at the origin (Caenorhabditis elegans)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Caenorhabditis elegans)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Caenorhabditis elegans)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Caenorhabditis elegans)
MCM10:active pre-replicative complex [nucleoplasm] (Caenorhabditis elegans)
active pre-replicative complex [nucleoplasm] (Caenorhabditis elegans)
CDC6:ORC:origin complex [nucleoplasm] (Caenorhabditis elegans)
ORC:origin of replication [nucleoplasm] (Caenorhabditis elegans)
orc-1 [nucleoplasm] (Caenorhabditis elegans)
Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7 (Caenorhabditis elegans)
MCM10:pre-replicative complex [nucleoplasm] (Caenorhabditis elegans)
pre-replicative complex [nucleoplasm] (Caenorhabditis elegans)
CDT1:CDC6:ORC:origin complex [nucleoplasm] (Caenorhabditis elegans)
CDC6:ORC:origin complex [nucleoplasm] (Caenorhabditis elegans)
ORC:origin of replication [nucleoplasm] (Caenorhabditis elegans)
orc-1 [nucleoplasm] (Caenorhabditis elegans)
pre-replicative complex [nucleoplasm] (Caenorhabditis elegans)
CDT1:CDC6:ORC:origin complex [nucleoplasm] (Caenorhabditis elegans)
CDC6:ORC:origin complex [nucleoplasm] (Caenorhabditis elegans)
ORC:origin of replication [nucleoplasm] (Caenorhabditis elegans)
orc-1 [nucleoplasm] (Caenorhabditis elegans)
Assembly of the pre-replicative complex (Caenorhabditis elegans)
Assembly of the ORC complex at the origin of replication (Caenorhabditis elegans)
Formation of ORC(1-5) complex (Caenorhabditis elegans)
ORC(1-5):origin of replication [nucleoplasm] (Caenorhabditis elegans)
ORC(1-5) [nucleoplasm] (Caenorhabditis elegans)
orc-1 [nucleoplasm] (Caenorhabditis elegans)
ORC1:origin of replication [nucleoplasm] (Caenorhabditis elegans)
orc-1 [nucleoplasm] (Caenorhabditis elegans)
ORC1 binds to H4K20me2 (Caenorhabditis elegans)
ORC1:H4K20Me2-nucleosome [nucleoplasm] (Caenorhabditis elegans)
orc-1 [nucleoplasm] (Caenorhabditis elegans)
orc-1 [nucleoplasm] (Caenorhabditis elegans)
ORC1 translocates to the nucleus (Caenorhabditis elegans)
orc-1 [nucleoplasm] (Caenorhabditis elegans)
Synthesis of DNA (Caenorhabditis elegans)
Switching of origins to a post-replicative state (Caenorhabditis elegans)
Orc1 removal from chromatin (Caenorhabditis elegans)
Orc1 is phosphorylated by cyclin A/CDK2 (Caenorhabditis elegans)
pre-replicative complex [nucleoplasm] (Caenorhabditis elegans)
CDT1:CDC6:ORC:origin complex [nucleoplasm] (Caenorhabditis elegans)
CDC6:ORC:origin complex [nucleoplasm] (Caenorhabditis elegans)
ORC:origin of replication [nucleoplasm] (Caenorhabditis elegans)
orc-1 [nucleoplasm] (Caenorhabditis elegans)
External Reference Information
External Reference
UniProt:Q9XX17
Gene Names
orc-1
Reference Genes
BioGPS Gene:176486 orc-1
ENSEMBL:WBGene00012650
KEGG Gene (Caenorhabditis elegans):CELE_Y39A1A.12 orc-1
Monarch:176486 orc-1
NCBI Gene:176486 orc-1
UCSC:Q9XX17 orc-1
Wormbase:WBGene00012650
Reference Transcript
RefSeq:NM_066946.4 orc-1
Other Identifiers
176486
18516786
193941_at
A_12_P102416
CE19131
CE_WBGene00012650_A
CE_WBGene00012650_B
CE_WBGene00012650_C
CGZ0044721
GO:0003824
GO:0005524
GO:0016787
GO:0016887
GO:0140657
WBGene00012650
Y39A1A.12
Y39A1A.12_1209-1268_0.917_15_B
Y39A1A.12_1362-1421_0.918_14_C
Y39A1A.12_1409-1468_0.916_16_A
Y39A1A_12P00874
Y39A1A_12P01557
Y39A1A_12P01707
cea2.p.76221
Participates
as an input of
ORC1 binds to H4K20me2 (Caenorhabditis elegans)
as an output of
ORC1 translocates to the nucleus (Caenorhabditis elegans)
as a component of
ORC1:H4K20Me2-nucleosome [nucleoplasm] (Caenorhabditis elegans)
ORC1:origin of replication [nucleoplasm] (Caenorhabditis elegans)
ORC(1-5) [nucleoplasm] (Caenorhabditis elegans)
ORC:origin of replication [nucleoplasm] (Caenorhabditis elegans)
Other forms of this molecule
phospho-orc-1 [cytosol]
phospho-orc-1 [nucleoplasm]
phospho-orc-1 [nucleoplasm]
orc-1 [cytosol]
Inferred From
ORC1 [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_499347.1
PRO
Q9XX17
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