Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
PSMC1 [cytosol]
Stable Identifier
R-CEL-68768
Type
Protein [EntityWithAccessionedSequence]
Species
Caenorhabditis elegans
Compartment
cytosol
Synonyms
O16368
Locations in the PathwayBrowser
Expand all
Cell Cycle (Caenorhabditis elegans)
Cell Cycle Checkpoints (Caenorhabditis elegans)
G1/S DNA Damage Checkpoints (Caenorhabditis elegans)
p53-Dependent G1/S DNA damage checkpoint (Caenorhabditis elegans)
p53-Dependent G1 DNA Damage Response (Caenorhabditis elegans)
Stabilization of p53 (Caenorhabditis elegans)
Autodegradation of the E3 ubiquitin ligase COP1 (Caenorhabditis elegans)
Proteasome mediated degradation of COP1 (Caenorhabditis elegans)
26S proteasome [cytosol] (Caenorhabditis elegans)
PSMC1 [cytosol] (Caenorhabditis elegans)
p53-Independent G1/S DNA damage checkpoint (Caenorhabditis elegans)
p53-Independent DNA Damage Response (Caenorhabditis elegans)
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A (Caenorhabditis elegans)
Proteolytic degradation of ubiquitinated-Cdc25A (Caenorhabditis elegans)
26S proteasome [cytosol] (Caenorhabditis elegans)
PSMC1 [cytosol] (Caenorhabditis elegans)
Cell Cycle, Mitotic (Caenorhabditis elegans)
Mitotic G2-G2/M phases (Caenorhabditis elegans)
G2/M Transition (Caenorhabditis elegans)
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis (Caenorhabditis elegans)
Proteasome degrades AURKA ubiquitinated by SCF-FBXL7 (Caenorhabditis elegans)
26S proteasome [cytosol] (Caenorhabditis elegans)
PSMC1 [cytosol] (Caenorhabditis elegans)
S Phase (Caenorhabditis elegans)
Synthesis of DNA (Caenorhabditis elegans)
Switching of origins to a post-replicative state (Caenorhabditis elegans)
CDK-mediated phosphorylation and removal of Cdc6 (Caenorhabditis elegans)
Ubiquitinated Cdc6 is degraded by the proteasome (Caenorhabditis elegans)
26S proteasome [cytosol] (Caenorhabditis elegans)
PSMC1 [cytosol] (Caenorhabditis elegans)
Orc1 removal from chromatin (Caenorhabditis elegans)
Ubiquitinated Orc1 is degraded by the proteasome (Caenorhabditis elegans)
26S proteasome [cytosol] (Caenorhabditis elegans)
PSMC1 [cytosol] (Caenorhabditis elegans)
Ubiquitin-dependent degradation of Cyclin D (Caenorhabditis elegans)
Proteasome mediated degradation of Cyclin D1 (Caenorhabditis elegans)
26S proteasome [cytosol] (Caenorhabditis elegans)
PSMC1 [cytosol] (Caenorhabditis elegans)
Cellular responses to stimuli (Caenorhabditis elegans)
Cellular responses to stress (Caenorhabditis elegans)
Cellular response to chemical stress (Caenorhabditis elegans)
KEAP1-NFE2L2 pathway (Caenorhabditis elegans)
26S proteasome degrades Ub-NFE2L2 (Caenorhabditis elegans)
26S proteasome [cytosol] (Caenorhabditis elegans)
PSMC1 [cytosol] (Caenorhabditis elegans)
Cellular response to hypoxia (Caenorhabditis elegans)
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha (Caenorhabditis elegans)
Proteasome proteolyzes ub-HIF-alpha (Caenorhabditis elegans)
26S proteasome [cytosol] (Caenorhabditis elegans)
PSMC1 [cytosol] (Caenorhabditis elegans)
DNA Replication (Caenorhabditis elegans)
Synthesis of DNA (Caenorhabditis elegans)
Switching of origins to a post-replicative state (Caenorhabditis elegans)
CDK-mediated phosphorylation and removal of Cdc6 (Caenorhabditis elegans)
Ubiquitinated Cdc6 is degraded by the proteasome (Caenorhabditis elegans)
26S proteasome [cytosol] (Caenorhabditis elegans)
PSMC1 [cytosol] (Caenorhabditis elegans)
Orc1 removal from chromatin (Caenorhabditis elegans)
Ubiquitinated Orc1 is degraded by the proteasome (Caenorhabditis elegans)
26S proteasome [cytosol] (Caenorhabditis elegans)
PSMC1 [cytosol] (Caenorhabditis elegans)
Immune System (Caenorhabditis elegans)
Adaptive Immune System (Caenorhabditis elegans)
Class I MHC mediated antigen processing & presentation (Caenorhabditis elegans)
Antigen processing-Cross presentation (Caenorhabditis elegans)
Cross-presentation of soluble exogenous antigens (endosomes) (Caenorhabditis elegans)
Proteasomal clevage of exogenous antigen (Caenorhabditis elegans)
26S proteasome [cytosol] (Caenorhabditis elegans)
PSMC1 [cytosol] (Caenorhabditis elegans)
Antigen processing: Ubiquitination & Proteasome degradation (Caenorhabditis elegans)
Proteasomal cleavage of substrate (Caenorhabditis elegans)
26S proteasome [cytosol] (Caenorhabditis elegans)
PSMC1 [cytosol] (Caenorhabditis elegans)
Metabolism (Caenorhabditis elegans)
Metabolism of amino acids and derivatives (Caenorhabditis elegans)
Metabolism of polyamines (Caenorhabditis elegans)
Regulation of ornithine decarboxylase (ODC) (Caenorhabditis elegans)
26S proteosome degrades ODC holoenzyme complex (Caenorhabditis elegans)
26S proteasome [cytosol] (Caenorhabditis elegans)
PSMC1 [cytosol] (Caenorhabditis elegans)
Metabolism of proteins (Caenorhabditis elegans)
Post-translational protein modification (Caenorhabditis elegans)
Asparagine N-linked glycosylation (Caenorhabditis elegans)
N-glycan trimming in the ER and Calnexin/Calreticulin cycle (Caenorhabditis elegans)
Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins (Caenorhabditis elegans)
Deglycosylation complex [endoplasmic reticulum membrane] (Caenorhabditis elegans)
PSMC1 [cytosol] (Caenorhabditis elegans)
Deubiquitination (Caenorhabditis elegans)
UCH proteinases (Caenorhabditis elegans)
ADRM1 binds 26S proteasome (Caenorhabditis elegans)
26S proteasome [cytosol] (Caenorhabditis elegans)
PSMC1 [cytosol] (Caenorhabditis elegans)
ADRM1:26S proteasome [cytosol] (Caenorhabditis elegans)
26S proteasome [cytosol] (Caenorhabditis elegans)
PSMC1 [cytosol] (Caenorhabditis elegans)
ADRM1:26S proteaseome binds UCHL5 (Caenorhabditis elegans)
ADRM1:26S proteasome [cytosol] (Caenorhabditis elegans)
26S proteasome [cytosol] (Caenorhabditis elegans)
PSMC1 [cytosol] (Caenorhabditis elegans)
ADRM1:26S proteasome:UCHL5 [cytosol] (Caenorhabditis elegans)
ADRM1:26S proteasome [cytosol] (Caenorhabditis elegans)
26S proteasome [cytosol] (Caenorhabditis elegans)
PSMC1 [cytosol] (Caenorhabditis elegans)
Ub-specific processing proteases (Caenorhabditis elegans)
ADRM1:26S proteaseome binds USP14 (Caenorhabditis elegans)
ADRM1:26S proteasome [cytosol] (Caenorhabditis elegans)
26S proteasome [cytosol] (Caenorhabditis elegans)
PSMC1 [cytosol] (Caenorhabditis elegans)
ADRM1:26S proteasome:USP14 [cytosol] (Caenorhabditis elegans)
ADRM1:26S proteasome [cytosol] (Caenorhabditis elegans)
26S proteasome [cytosol] (Caenorhabditis elegans)
PSMC1 [cytosol] (Caenorhabditis elegans)
Neddylation (Caenorhabditis elegans)
26S proteasome degrades HIFalpha (Caenorhabditis elegans)
26S proteasome [cytosol] (Caenorhabditis elegans)
PSMC1 [cytosol] (Caenorhabditis elegans)
26S proteasome degrades Ub-NFE2L2 (Caenorhabditis elegans)
26S proteasome [cytosol] (Caenorhabditis elegans)
PSMC1 [cytosol] (Caenorhabditis elegans)
Signal Transduction (Caenorhabditis elegans)
Intracellular signaling by second messengers (Caenorhabditis elegans)
PIP3 activates AKT signaling (Caenorhabditis elegans)
PTEN Regulation (Caenorhabditis elegans)
Regulation of PTEN stability and activity (Caenorhabditis elegans)
Proteasome degrades polyubiquitinated PTEN (Caenorhabditis elegans)
26S proteasome [cytosol] (Caenorhabditis elegans)
PSMC1 [cytosol] (Caenorhabditis elegans)
MAPK family signaling cascades (Caenorhabditis elegans)
MAPK6/MAPK4 signaling (Caenorhabditis elegans)
MAPK6 is degraded by the 26S proteasome (Caenorhabditis elegans)
26S proteasome [cytosol] (Caenorhabditis elegans)
PSMC1 [cytosol] (Caenorhabditis elegans)
Signaling by WNT (Caenorhabditis elegans)
Beta-catenin independent WNT signaling (Caenorhabditis elegans)
PCP/CE pathway (Caenorhabditis elegans)
Asymmetric localization of PCP proteins (Caenorhabditis elegans)
PRICKLE1 is degraded by the proteasome (Caenorhabditis elegans)
26S proteasome [cytosol] (Caenorhabditis elegans)
PSMC1 [cytosol] (Caenorhabditis elegans)
Degradation of beta-catenin by the destruction complex (Caenorhabditis elegans)
Degradation of ubiquitinated beta catenin by the proteasome (Caenorhabditis elegans)
26S proteasome [cytosol] (Caenorhabditis elegans)
PSMC1 [cytosol] (Caenorhabditis elegans)
TCF dependent signaling in response to WNT (Caenorhabditis elegans)
Degradation of DVL (Caenorhabditis elegans)
Ubiquitinated DVL1 is degraded by the proteasome (Caenorhabditis elegans)
26S proteasome [cytosol] (Caenorhabditis elegans)
PSMC1 [cytosol] (Caenorhabditis elegans)
Transport of small molecules (Caenorhabditis elegans)
ABC-family proteins mediated transport (Caenorhabditis elegans)
misfolded CFTR is degraded by the 26S proteasome (Caenorhabditis elegans)
26S proteasome [cytosol] (Caenorhabditis elegans)
PSMC1 [cytosol] (Caenorhabditis elegans)
External Reference Information
External Reference
UniProt:O16368
Reference Genes
BioGPS Gene:178988
ENSEMBL:WBGene00004502
Monarch:178988
NCBI Gene:178988
UCSC:O16368
Wormbase:WBGene00004502
Reference Transcript
RefSeq:NM_072157.6
Other Identifiers
173034_s_at
178988
18588836
190174_s_at
A_12_P100607
CE09799
CE_WBGene00004502_A
CE_WBGene00004502_C
CGZ0018958
F29G9.5
F29G9.5_1049-1108_0.930_6_B
F29G9.5_1161-1220_0.958_1_A
F29G9.5_1247-1306_0.927_8_C
F29G9_5P00117
F29G9_5P00708
F29G9_5P01208
GO:0003824
GO:0005524
GO:0016787
GO:0016887
GO:0140657
WBGene00004502
cea2.p.115523
Participates
as a component of
Deglycosylation complex [endoplasmic reticulum membrane] (Caenorhabditis elegans)
26S proteasome [cytosol] (Caenorhabditis elegans)
Other forms of this molecule
PSMC1 [nucleoplasm]
Inferred From
PSMC1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_504558.1
PRO
O16368
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
