Reactome | tofu-2 [nucleoplasm]

tofu-2 [nucleoplasm]

Stable Identifier

R-CEL-71953-2

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

nucleoplasm

Synonyms

HNRNPU, Q19614

Locations in the PathwayBrowser

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Metabolism of RNA (Caenorhabditis elegans)

- Processing of Capped Intron-Containing Pre-mRNA (Caenorhabditis elegans)
  - Formation of pre-mRNPs (Caenorhabditis elegans)
    - Alternative Splicing Factors [nucleoplasm] (Caenorhabditis elegans)
      - Homologues of HNRNPU [nucleoplasm] (Caenorhabditis elegans)
        
        tofu-2 [nucleoplasm] (Caenorhabditis elegans)
    - capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Caenorhabditis elegans)
      - Alternative Splicing Factors [nucleoplasm] (Caenorhabditis elegans)
        
        Homologues of HNRNPU [nucleoplasm] (Caenorhabditis elegans)
        
        tofu-2 [nucleoplasm] (Caenorhabditis elegans)
  - mRNA 3'-end processing (Caenorhabditis elegans)
    - mRNA Polyadenylation (Caenorhabditis elegans)
      - Core CPA complex binds capped pre-mRNA (Caenorhabditis elegans)
        
        Core CPA complex:Spliceosomal A complex (uncleaved pre-mRNA) [nucleoplasm] (Caenorhabditis elegans)
        
        Spliceosomal A complex (capped, methylated pre-mRNA) [nucleoplasm] (Caenorhabditis elegans)
        
        capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Caenorhabditis elegans)
        
        Alternative Splicing Factors [nucleoplasm] (Caenorhabditis elegans)
        
        Homologues of HNRNPU [nucleoplasm] (Caenorhabditis elegans)
        
        tofu-2 [nucleoplasm] (Caenorhabditis elegans)
        
        Spliceosomal A complex (capped, methylated pre-mRNA) [nucleoplasm] (Caenorhabditis elegans)
        
        capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Caenorhabditis elegans)
        
        Alternative Splicing Factors [nucleoplasm] (Caenorhabditis elegans)
        
        Homologues of HNRNPU [nucleoplasm] (Caenorhabditis elegans)
        
        tofu-2 [nucleoplasm] (Caenorhabditis elegans)
      - PABPN1-stimulated PAPOL synthesizes polyA tail at distal 3'UTR PAS (Caenorhabditis elegans)
        
        Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at distal 3'UTR PAS) [nucleoplasm] (Caenorhabditis elegans)
        
        Spliceosomal A complex (pre-mRNA polyadenylated at distal 3'UTR PAS) [nucleoplasm] (Caenorhabditis elegans)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA polyadenylated at distal 3'UTR PAS) [nucleoplasm] (Caenorhabditis elegans)
        
        Alternative Splicing Factors [nucleoplasm] (Caenorhabditis elegans)
        
        Homologues of HNRNPU [nucleoplasm] (Caenorhabditis elegans)
        
        tofu-2 [nucleoplasm] (Caenorhabditis elegans)
        
        Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at distal 3'UTR PAS) [nucleoplasm] (Caenorhabditis elegans)
        
        Spliceosomal A complex (pre-mRNA cleaved at distal 3'UTR PAS) [nucleoplasm] (Caenorhabditis elegans)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA cleaved at distal 3'UTR PAS) [nucleoplasm] (Caenorhabditis elegans)
        
        Alternative Splicing Factors [nucleoplasm] (Caenorhabditis elegans)
        
        Homologues of HNRNPU [nucleoplasm] (Caenorhabditis elegans)
        
        tofu-2 [nucleoplasm] (Caenorhabditis elegans)
      - PABPN1-stimulated PAPOL synthesizes polyA tail at intronic PAS (Caenorhabditis elegans)
        
        Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at intronic PAS) [nucleoplasm] (Caenorhabditis elegans)
        
        Spliceosomal A complex (pre-mRNA polyadenylated at intronic PAS) [nucleoplasm] (Caenorhabditis elegans)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA polyadenylated at intronic PAS) [nucleoplasm] (Caenorhabditis elegans)
        
        Alternative Splicing Factors [nucleoplasm] (Caenorhabditis elegans)
        
        Homologues of HNRNPU [nucleoplasm] (Caenorhabditis elegans)
        
        tofu-2 [nucleoplasm] (Caenorhabditis elegans)
        
        Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at intronic PAS) [nucleoplasm] (Caenorhabditis elegans)
        
        Spliceosomal A complex (pre-mRNA cleaved at intronal PAS) [nucleoplasm] (Caenorhabditis elegans)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA cleaved at intronic PAS) [nucleoplasm] (Caenorhabditis elegans)
        
        Alternative Splicing Factors [nucleoplasm] (Caenorhabditis elegans)
        
        Homologues of HNRNPU [nucleoplasm] (Caenorhabditis elegans)
        
        tofu-2 [nucleoplasm] (Caenorhabditis elegans)
      - PABPN1-stimulated PAPOL synthesizes polyA tail at proximal 3'UTR PAS (Caenorhabditis elegans)
        
        Ub-K63-CPA:PABPN1:Spliceosomal A complex (pre-mRNA polyadenylated at proximal 3'UTR PAS) [nucleoplasm] (Caenorhabditis elegans)
        
        Spliceosomal A complex (pre-mRNA polyadenylated at proximal 3'UTR PAS) [nucleoplasm] (Caenorhabditis elegans)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA polyadenylated at proximal 3'UTR PAS) [nucleoplasm] (Caenorhabditis elegans)
        
        Alternative Splicing Factors [nucleoplasm] (Caenorhabditis elegans)
        
        Homologues of HNRNPU [nucleoplasm] (Caenorhabditis elegans)
        
        tofu-2 [nucleoplasm] (Caenorhabditis elegans)
        
        Ub-K63-CPA:Spliceosomal A complex (pre-mRNA cleaved at proximal 3'UTR PAS) [nucleoplasm] (Caenorhabditis elegans)
        
        Spliceosomal A complex (pre-mRNA cleaved at proximal 3'UTR PAS) [nucleoplasm] (Caenorhabditis elegans)
        
        capped, methylated pre-mRNP:CBC complex (pre-mRNA cleaved at proximal 3'UTR PAS) [nucleoplasm] (Caenorhabditis elegans)
        
        Alternative Splicing Factors [nucleoplasm] (Caenorhabditis elegans)
        
        Homologues of HNRNPU [nucleoplasm] (Caenorhabditis elegans)
        
        tofu-2 [nucleoplasm] (Caenorhabditis elegans)
      - PP1 dephosphorylates RNA Pol II (Caenorhabditis elegans)
        
        CPA:Spliceosomal A complex (uncleaved pre-mRNA) [nucleoplasm] (Caenorhabditis elegans)
        
        Spliceosomal A complex (capped, methylated pre-mRNA) [nucleoplasm] (Caenorhabditis elegans)
        
        capped, methylated pre-mRNP:CBC complex [nucleoplasm] (Caenorhabditis elegans)
        
        Alternative Splicing Factors [nucleoplasm] (Caenorhabditis elegans)
        
        Homologues of HNRNPU [nucleoplasm] (Caenorhabditis elegans)
        
        tofu-2 [nucleoplasm] (Caenorhabditis elegans)
        
        CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Caenorhabditis elegans)
        
        Spliceosomal A complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Caenorhabditis elegans)
        
        capped, methylated pre-mRNP:CBC complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Caenorhabditis elegans)
        
        Alternative Splicing Factors [nucleoplasm] (Caenorhabditis elegans)
        
        Homologues of HNRNPU [nucleoplasm] (Caenorhabditis elegans)
        
        tofu-2 [nucleoplasm] (Caenorhabditis elegans)
      - RBBP6 activates CPSF complex (Caenorhabditis elegans)
        
        CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Caenorhabditis elegans)
        
        Spliceosomal A complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Caenorhabditis elegans)
        
        capped, methylated pre-mRNP:CBC complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Caenorhabditis elegans)
        
        Alternative Splicing Factors [nucleoplasm] (Caenorhabditis elegans)
        
        Homologues of HNRNPU [nucleoplasm] (Caenorhabditis elegans)
        
        tofu-2 [nucleoplasm] (Caenorhabditis elegans)
        
        Ub-K63-CPA:Spliceosomal A complex (uncleaved pre-mRNA, RNA Pol II Ser2 dephosphorylated) [nucleoplasm] (Caenorhabditis elegans)
        
        Spliceosomal A complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Caenorhabditis elegans)
        
        capped, methylated pre-mRNP:CBC complex (RNA Pol II Ser5 dephosphorylated) [nucleoplasm] (Caenorhabditis elegans)
        
        Alternative Splicing Factors [nucleoplasm] (Caenorhabditis elegans)
        
        Homologues of HNRNPU [nucleoplasm] (Caenorhabditis elegans)
        
        tofu-2 [nucleoplasm] (Caenorhabditis elegans)
  - mRNA Splicing (Caenorhabditis elegans)
    - mRNA Splicing - Major Pathway (Caenorhabditis elegans)
      - Formation of the Spliceosomal Bact complex (Caenorhabditis elegans)
        
        Spliceosomal B complex [nucleoplasm] (Caenorhabditis elegans)
        
        capped, methylated, polyadenylated pre-mRNP:CBC complex [nucleoplasm] (Caenorhabditis elegans)
        
        Alternative Splicing Factors [nucleoplasm] (Caenorhabditis elegans)
        
        Homologues of HNRNPU [nucleoplasm] (Caenorhabditis elegans)
        
        tofu-2 [nucleoplasm] (Caenorhabditis elegans)
        
        Spliceosomal Bact complex [nucleoplasm] (Caenorhabditis elegans)
        
        capped, methylated, polyadenylated pre-mRNP:CBC complex [nucleoplasm] (Caenorhabditis elegans)
        
        Alternative Splicing Factors [nucleoplasm] (Caenorhabditis elegans)
        
        Homologues of HNRNPU [nucleoplasm] (Caenorhabditis elegans)
        
        tofu-2 [nucleoplasm] (Caenorhabditis elegans)
      - Formation of the Spliceosomal C complex containing intron lariat (Caenorhabditis elegans)
        
        Spliceosomal B* complex [nucleoplasm] (Caenorhabditis elegans)
        
        capped, methylated, polyadenylated pre-mRNP:CBC complex [nucleoplasm] (Caenorhabditis elegans)
        
        Alternative Splicing Factors [nucleoplasm] (Caenorhabditis elegans)
        
        Homologues of HNRNPU [nucleoplasm] (Caenorhabditis elegans)
        
        tofu-2 [nucleoplasm] (Caenorhabditis elegans)
        
        Spliceosomal C complex [nucleoplasm] (Caenorhabditis elegans)
        
        Alternative Splicing Factors [nucleoplasm] (Caenorhabditis elegans)
        
        Homologues of HNRNPU [nucleoplasm] (Caenorhabditis elegans)
        
        tofu-2 [nucleoplasm] (Caenorhabditis elegans)
      - Formation of the Spliceosomal C* complex (Caenorhabditis elegans)
        
        Spliceosomal C complex [nucleoplasm] (Caenorhabditis elegans)
        
        Alternative Splicing Factors [nucleoplasm] (Caenorhabditis elegans)
        
        Homologues of HNRNPU [nucleoplasm] (Caenorhabditis elegans)
        
        tofu-2 [nucleoplasm] (Caenorhabditis elegans)
        
        Spliceosomal C* complex [nucleoplasm] (Caenorhabditis elegans)
        
        Alternative Splicing Factors [nucleoplasm] (Caenorhabditis elegans)
        
        Homologues of HNRNPU [nucleoplasm] (Caenorhabditis elegans)
        
        tofu-2 [nucleoplasm] (Caenorhabditis elegans)
      - Formation of the Spliceosomal P complex and exon ligation (Caenorhabditis elegans)
        
        Spliceosomal C* complex [nucleoplasm] (Caenorhabditis elegans)
        
        Alternative Splicing Factors [nucleoplasm] (Caenorhabditis elegans)
        
        Homologues of HNRNPU [nucleoplasm] (Caenorhabditis elegans)
        
        tofu-2 [nucleoplasm] (Caenorhabditis elegans)
        
        Spliceosomal P complex [nucleoplasm] (Caenorhabditis elegans)
        
        spliced mRNA:EJC:CBC complex:Alternative splicing factor [nucleoplasm] (Caenorhabditis elegans)
        
        Alternative Splicing Factors [nucleoplasm] (Caenorhabditis elegans)
        
        Homologues of HNRNPU [nucleoplasm] (Caenorhabditis elegans)
        
        tofu-2 [nucleoplasm] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:Q19614

Gene Names

tofu-2

Reference Genes

BioGPS Gene:179089 tofu-2

CTD Gene:179089 tofu-2

ENSEMBL:WBGene00017620

KEGG:cel:CELE_F20A1.9 tofu-2

Monarch:179089 tofu-2

NCBI Gene:179089 tofu-2

UCSC:Q19614 tofu-2

Wormbase:WBGene00017620

Wormbase:WBGene00017620 tofu-2

Reference Transcript

RefSeq:NM_072385.7 tofu-2

Other Identifiers

179089

GO:0000380

GO:0003723

GO:0003824

GO:0004518

GO:0004519

GO:0004521

GO:0005515

GO:0005634

GO:0005737

GO:0005739

GO:0016787

GO:0140098

GO:0140990

GO:1902555

Participates

as a member of

Homologues of HNRNPU [nucleoplasm] (Caenorhabditis elegans)

Inferred From

HNRNPU [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_504786.2

ENSEMBL

WBGene00017620, F20A1.9.1, F20A1.9.1

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