Reactome | rps-24 [cytosol]

rps-24 [cytosol]

Stable Identifier

R-CEL-72355

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

cytosol

Synonyms

RPS24, Q1XFY9

Locations in the PathwayBrowser

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Metabolism of RNA (Caenorhabditis elegans)

- Nonsense-Mediated Decay (NMD) (Caenorhabditis elegans)
  - Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Caenorhabditis elegans)
    - SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Caenorhabditis elegans)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Caenorhabditis elegans)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
        
        80S ribosome [cytosol] (Caenorhabditis elegans)
        
        40S ribosomal complex [cytosol] (Caenorhabditis elegans)
        
        rps-24 [cytosol] (Caenorhabditis elegans)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Caenorhabditis elegans)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
        
        80S ribosome [cytosol] (Caenorhabditis elegans)
        
        40S ribosomal complex [cytosol] (Caenorhabditis elegans)
        
        rps-24 [cytosol] (Caenorhabditis elegans)
    - SMG6 hydrolyzes mRNA with premature termination codon (Caenorhabditis elegans)
      - Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Caenorhabditis elegans)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
        
        80S ribosome [cytosol] (Caenorhabditis elegans)
        
        40S ribosomal complex [cytosol] (Caenorhabditis elegans)
        
        rps-24 [cytosol] (Caenorhabditis elegans)
    - UPF1 binds an mRNP with a termination codon preceding an Exon Junction Complex (Caenorhabditis elegans)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Caenorhabditis elegans)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
        
        80S ribosome [cytosol] (Caenorhabditis elegans)
        
        40S ribosomal complex [cytosol] (Caenorhabditis elegans)
        
        rps-24 [cytosol] (Caenorhabditis elegans)
      - Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
        
        80S ribosome [cytosol] (Caenorhabditis elegans)
        
        40S ribosomal complex [cytosol] (Caenorhabditis elegans)
        
        rps-24 [cytosol] (Caenorhabditis elegans)
  - Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Caenorhabditis elegans)
    - Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Caenorhabditis elegans)
      - Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
        
        80S ribosome [cytosol] (Caenorhabditis elegans)
        
        40S ribosomal complex [cytosol] (Caenorhabditis elegans)
        
        rps-24 [cytosol] (Caenorhabditis elegans)
      - UPF1:eRF3 Complex on Translated mRNA [cytosol] (Caenorhabditis elegans)
        
        Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Caenorhabditis elegans)
        
        80S ribosome [cytosol] (Caenorhabditis elegans)
        
        40S ribosomal complex [cytosol] (Caenorhabditis elegans)
        
        rps-24 [cytosol] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:Q1XFY9

Gene Names

rps-24

Reference Genes

BioGPS Gene:176858 rps-24

ENSEMBL:WBGene00004493

Monarch:176858 rps-24

NCBI Gene:176858 rps-24

UCSC:Q1XFY9 rps-24

Wormbase:WBGene00004493

Reference Transcript

RefSeq:NM_067514.4 rps-24

Other Identifiers

175100_s_at

176858

18541826

A_12_P139935

CE29465

CE_WBGene00004493_A

CGZ0033849

GO:0003735

GO:0005198

GO:0005840

GO:0006412

GO:0043226

T07A9.11

T07A9.11_128-187_0.960_1_A

T07A9.11_2-61_0.886_8_C

T07A9.11_333-392_0.954_2_B

T07A9_11P00006

T07A9_11P00253

T07A9_11P00278

WBGene00004493

Participates

as a component of

40S ribosomal complex [cytosol] (Caenorhabditis elegans)

Other forms of this molecule

rps-24 [nucleoplasm]

Inferred From

RPS24 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_499915.2

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