Reactome | rnf-5 [endoplasmic reticulum membrane]

rnf-5 [endoplasmic reticulum membrane]

Stable Identifier

R-CEL-8861819

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

endoplasmic reticulum membrane

Synonyms

RNF185, Q09463

Locations in the PathwayBrowser

Expand all

Immune System (Caenorhabditis elegans)

- Adaptive Immune System (Caenorhabditis elegans)
  - Regulation of T cell activation by CD28 family (Caenorhabditis elegans)
    - Co-inhibition by PD-1 (Caenorhabditis elegans)
      - Regulation of PD-L1(CD274) expression (Caenorhabditis elegans)
        
        Regulation of PD-L1(CD274) Post-translational modification (Caenorhabditis elegans)
        
        AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) (Caenorhabditis elegans)
        
        Ubiquitination of CD274 by ERAD complex (Caenorhabditis elegans)
        
        ERAD complex [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        rnf-5 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        Poly-Ub-p-S195-CD274:ERAD complex [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        p-S195-CD274:ERAD complex [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        ERAD complex [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        rnf-5 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        p-S195-CD274:ERAD complex [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        ERAD complex [endoplasmic reticulum membrane] (Caenorhabditis elegans)
        
        rnf-5 [endoplasmic reticulum membrane] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:Q09463

Gene Names

rnf-5

Reference Genes

BioGPS Gene:175532 rnf-5

ENSEMBL:WBGene00004381

KEGG:cel:CELE_C16C10.7 rnf-5

Monarch:175532 rnf-5

NCBI Gene:175532 rnf-5

UCSC:Q09463 rnf-5

Wormbase:WBGene00004381

Wormbase:WBGene00004381 rnf-5

Reference Transcript

RefSeq:NM_065429.4 rnf-5

Other Identifiers

175532

GO:0003824

GO:0004842

GO:0005515

GO:0005634

GO:0005737

GO:0005783

GO:0005886

GO:0005925

GO:0006511

GO:0008270

GO:0012505

GO:0016020

GO:0016567

GO:0016740

GO:0018996

GO:0030054

GO:0030163

GO:0036503

GO:0040039

GO:0044390

GO:0046872

GO:0048856

GO:0048870

GO:0055002

GO:0055120

GO:0061630

GO:0070161

GO:0140096

Participates

as a component of

ERAD complex [endoplasmic reticulum membrane] (Caenorhabditis elegans)

Other forms of this molecule

rnf-5 [endoplasmic reticulum membrane]

Inferred From

RNF5,RNF185 [endoplasmic reticulum membrane] (Homo sapiens)

RNF185 [endoplasmic reticulum membrane] (Homo sapiens)

Cross References

RefSeq

NP_497830.1

ENSEMBL

WBGene00004381, C16C10.7a.1, C16C10.7a.1

PRO

Q09463

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P49023 PXN	4	p-Y31,Y118-PXN [cytosol] (R-HSA-5218693) PXN [cytosol] (R-HSA-210014) p-Y-PXN [plasma membrane] (R-HSA-9031680) PXN [plasma membrane] (R-HSA-180493)	0.524	2