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phospho-hmp-2 [cytosol]
Stable Identifier
R-CEL-8942374
Type
Protein [EntityWithAccessionedSequence]
Species
Caenorhabditis elegans
Compartment
cytosol
Synonyms
p-S33,S37,T41,S45 CTNNB1, O44326
Locations in the PathwayBrowser
Expand all
Signal Transduction (Caenorhabditis elegans)
Signaling by WNT (Caenorhabditis elegans)
Degradation of beta-catenin by the destruction complex (Caenorhabditis elegans)
Association of beta-catenin with the RBX1:SCF(beta-TrCP1) ubiquitin ligase complex (Caenorhabditis elegans)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Caenorhabditis elegans)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Caenorhabditis elegans)
phospho-hmp-2 [cytosol] (Caenorhabditis elegans)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Caenorhabditis elegans)
phospho-hmp-2 [cytosol] (Caenorhabditis elegans)
Beta-catenin phosphorylation cascade (Caenorhabditis elegans)
Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 (Caenorhabditis elegans)
p-S33,S37,T41,S45-beta-catenin:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Caenorhabditis elegans)
phospho-hmp-2 [cytosol] (Caenorhabditis elegans)
Degradation of ubiquitinated beta catenin by the proteasome (Caenorhabditis elegans)
ubiquitinated phospho-beta-catenin:RBX1:SCF(beta-TrCP1) complex [cytosol] (Caenorhabditis elegans)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Caenorhabditis elegans)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Caenorhabditis elegans)
phospho-hmp-2 [cytosol] (Caenorhabditis elegans)
Dissociation of beta-catenin from Axin and association of beta catenin with phospho-(20 aa) APC in the detruction complex (Caenorhabditis elegans)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Caenorhabditis elegans)
phospho-hmp-2 [cytosol] (Caenorhabditis elegans)
Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1) (Caenorhabditis elegans)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Caenorhabditis elegans)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Caenorhabditis elegans)
phospho-hmp-2 [cytosol] (Caenorhabditis elegans)
ubiquitinated phospho-beta-catenin:RBX1:SCF(beta-TrCP1) complex [cytosol] (Caenorhabditis elegans)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Caenorhabditis elegans)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Caenorhabditis elegans)
phospho-hmp-2 [cytosol] (Caenorhabditis elegans)
Phosphorylation of APC component of the destruction complex (Caenorhabditis elegans)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Caenorhabditis elegans)
phospho-hmp-2 [cytosol] (Caenorhabditis elegans)
p-S33,S37,T41,S45-beta-catenin:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Caenorhabditis elegans)
phospho-hmp-2 [cytosol] (Caenorhabditis elegans)
External Reference Information
External Reference
UniProt:O44326
Gene Names
hmp-2
Reference Genes
BioGPS Gene:173338 hmp-2
ENSEMBL:WBGene00001979
Monarch:173338 hmp-2
NCBI Gene:173338 hmp-2
UCSC:O44326 hmp-2
Wormbase:WBGene00001979
Reference Transcript
RefSeq:NM_001265497.1 hmp-2
Other Identifiers
173338
18457881
193907_at
A_12_P105979
CE19974
CE_WBGene00001979_A
CE_WBGene00001979_B
CE_WBGene00001979_C
CGZ0027911
GO:0005515
GO:0007155
GO:0045296
K05C4.6
K05C4.6_1085-1144_0.879_28_B
K05C4.6_1284-1343_0.903_17_A
K05C4.6_1753-1812_0.955_2_C
K05C4_6P00599
K05C4_6P00786
K05C4_6P01752
WBGene00001979
cea2.c.04836
Participates
as a component of
p-S33,S37,T41,S45-beta-catenin:p-AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] (Caenorhabditis elegans)
p-S33,S37,T41,S45 CTNNB1:p-AXIN:CK1alpha:GSK3B:phospho-ub-APC (20 aa repeat region):PP2A:AMER1 complex [cytosol] (Caenorhabditis elegans)
Other forms of this molecule
hmp-2 [cytosol]
hmp-2 [specific granule lumen]
hmp-2 [extracellular region]
hmp-2 [ficolin-1-rich granule lumen]
phospho-hmp-2 [nucleoplasm]
phospho-hmp-2 [cytosol]
hmp-2 [plasma membrane]
hmp-2 [plasma membrane]
phospho-hmp-2 [cytosol]
phospho-hmp-2 [cytosol]
phospho-hmp-2 [cytosol]
hmp-2 [cytosol]
hmp-2 [cytosol]
hmp-2 [cytosol]
hmp-2 [nucleoplasm]
Inferred From
p-S33,S37,T41,S45 CTNNB1 [cytosol]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-serine at 45 (in Homo sapiens)
Coordinate
45
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-threonine at 41 (in Homo sapiens)
Coordinate
41
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-serine at 37 (in Homo sapiens)
Coordinate
37
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 33 (in Homo sapiens)
Coordinate
33
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
NP_001252426.1
PRO
O44326
PDB
4R10
,
5XA5
,
4R0Z
,
4R11
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q967F4 HMR1
0.785
5
UniProt:Q09506
1
txbp-3 [cytosol]
(R-CEL-5666217)
0.553
2
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