Reactome | ASB3 [cytosol]

ASB3 [cytosol]

Stable Identifier

R-CEL-975411

Type

Protein [EntityWithAccessionedSequence]

Species

Caenorhabditis elegans

Compartment

cytosol

Synonyms

O18152

Locations in the PathwayBrowser

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Immune System (Caenorhabditis elegans)

- Adaptive Immune System (Caenorhabditis elegans)
  - Class I MHC mediated antigen processing & presentation (Caenorhabditis elegans)
    - Antigen processing: Ubiquitination & Proteasome degradation (Caenorhabditis elegans)
      - Interaction of E3 with substrate and E2-Ub complex (Caenorhabditis elegans)
        
        Ag-substrate:E3:E2:Ub [cytosol] (Caenorhabditis elegans)
        
        E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
        
        RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Caenorhabditis elegans)
        
        ASB family [cytosol] (Caenorhabditis elegans)
        
        ASB3 [cytosol] (Caenorhabditis elegans)
        
        E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
        
        RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Caenorhabditis elegans)
        
        ASB family [cytosol] (Caenorhabditis elegans)
        
        ASB3 [cytosol] (Caenorhabditis elegans)
      - Polyubiquitination of substrate (Caenorhabditis elegans)
        
        E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
        
        RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Caenorhabditis elegans)
        
        ASB family [cytosol] (Caenorhabditis elegans)
        
        ASB3 [cytosol] (Caenorhabditis elegans)
        
        E3:K48-polyubiquitinated substrate [cytosol] (Caenorhabditis elegans)
        
        E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
        
        RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Caenorhabditis elegans)
        
        ASB family [cytosol] (Caenorhabditis elegans)
        
        ASB3 [cytosol] (Caenorhabditis elegans)
        
        E3:Ub:substrate [cytosol] (Caenorhabditis elegans)
        
        E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
        
        RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Caenorhabditis elegans)
        
        ASB family [cytosol] (Caenorhabditis elegans)
        
        ASB3 [cytosol] (Caenorhabditis elegans)
      - Release of E3 from polyubiquitinated substrate (Caenorhabditis elegans)
        
        E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
        
        RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Caenorhabditis elegans)
        
        ASB family [cytosol] (Caenorhabditis elegans)
        
        ASB3 [cytosol] (Caenorhabditis elegans)
        
        E3:K48-polyubiquitinated substrate [cytosol] (Caenorhabditis elegans)
        
        E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
        
        RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Caenorhabditis elegans)
        
        ASB family [cytosol] (Caenorhabditis elegans)
        
        ASB3 [cytosol] (Caenorhabditis elegans)
      - Transfer of Ub from E2 to substrate and release of E2 (Caenorhabditis elegans)
        
        Ag-substrate:E3:E2:Ub [cytosol] (Caenorhabditis elegans)
        
        E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
        
        RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Caenorhabditis elegans)
        
        ASB family [cytosol] (Caenorhabditis elegans)
        
        ASB3 [cytosol] (Caenorhabditis elegans)
        
        E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
        
        RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Caenorhabditis elegans)
        
        ASB family [cytosol] (Caenorhabditis elegans)
        
        ASB3 [cytosol] (Caenorhabditis elegans)
        
        E3:Ub:substrate [cytosol] (Caenorhabditis elegans)
        
        E3 ligases in proteasomal degradation [cytosol] (Caenorhabditis elegans)
        
        RNF7 (RBX2):CUL5:EloB/C:ASB [cytosol] (Caenorhabditis elegans)
        
        ASB family [cytosol] (Caenorhabditis elegans)
        
        ASB3 [cytosol] (Caenorhabditis elegans)

Metabolism of proteins (Caenorhabditis elegans)

- Post-translational protein modification (Caenorhabditis elegans)
  - Neddylation (Caenorhabditis elegans)
    - CAND1 binds cytosolic CRL E3 ubiquitin ligases (Caenorhabditis elegans)
      - CRL E3 ubiquitin ligase:CAND1 [cytosol] (Caenorhabditis elegans)
        
        CRL E3 ubiquitin ligases [cytosol] (Caenorhabditis elegans)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Caenorhabditis elegans)
        
        CUL5-box protein [cytosol] (Caenorhabditis elegans)
        
        ASB3 [cytosol] (Caenorhabditis elegans)
      - CRL E3 ubiquitin ligases [cytosol] (Caenorhabditis elegans)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Caenorhabditis elegans)
        
        CUL5-box protein [cytosol] (Caenorhabditis elegans)
        
        ASB3 [cytosol] (Caenorhabditis elegans)
    - COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes (Caenorhabditis elegans)
      - CRL E3 ubiquitin ligase complex:COMMDs:CCDC22:DCUN1Ds [cytosol] (Caenorhabditis elegans)
        
        CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Caenorhabditis elegans)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Caenorhabditis elegans)
        
        CUL5-box protein [cytosol] (Caenorhabditis elegans)
        
        ASB3 [cytosol] (Caenorhabditis elegans)
      - NEDD8 CRL E3 ubiquitin ligases:COMMDs:CCDC22:DCUN1Ds [cytosol] (Caenorhabditis elegans)
        
        NEDD8-CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Caenorhabditis elegans)
        
        NEDD8-CRL5 E3 ligase [cytosol] (Caenorhabditis elegans)
        
        CUL5-box protein [cytosol] (Caenorhabditis elegans)
        
        ASB3 [cytosol] (Caenorhabditis elegans)

External Reference Information

External Reference

UniProt:O18152

Reference Genes

BioGPS Gene:176566

CTD Gene:176566

ENSEMBL:WBGene00012124

Monarch:176566

NCBI Gene:176566

UCSC:O18152

Wormbase:WBGene00012124

Reference Transcript

RefSeq:NM_067060.5

Other Identifiers

176566

18516081

190357_at

A_12_P113014

CE16523

CE_WBGene00012124_A

CE_WBGene00012124_B

CGZ0037474

GO:0005515

GO:0005929

GO:0043226

GO:0097543

GO:1904108

T28D6.4

T28D6.4_1611-1670_0.859_36_C

T28D6.4_1963-2022_0.883_19_B

T28D6.4_2547-2606_0.897_11_A

T28D6_4P01940

T28D6_4P02251

T28D6_4P02872

WBGene00012124

cea2.3.25365

cea2.p.75103

Participates

as a member of

Inferred From

ASB3 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_499461.1

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