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BUB1B [cytosol]
Stable Identifier
R-CFA-141436
Type
Protein [EntityWithAccessionedSequence]
Species
Canis familiaris
Compartment
cytosol
Synonyms
BUB1B, F1PLV9
Locations in the PathwayBrowser
Expand all
Cell Cycle (Canis familiaris)
Cell Cycle Checkpoints (Canis familiaris)
Mitotic Spindle Checkpoint (Canis familiaris)
Amplification of signal from the kinetochores (Canis familiaris)
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal (Canis familiaris)
MAD2 associates with the Mad1 kinetochore complex (Canis familiaris)
Kinetochore:Mad1:MAD2 Complex [cytosol] (Canis familiaris)
Mad1:kinetochore complex [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
Mitotic checkpoint complex [cytosol] (Canis familiaris)
BUB1B [cytosol] (Canis familiaris)
Mad1:kinetochore complex [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
Mitotic checkpoint complex [cytosol] (Canis familiaris)
BUB1B [cytosol] (Canis familiaris)
MAD2 converted to an inhibitory state via interaction with Mad1 (Canis familiaris)
Kinetochore:Mad1:MAD2 Complex [cytosol] (Canis familiaris)
Mad1:kinetochore complex [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
Mitotic checkpoint complex [cytosol] (Canis familiaris)
BUB1B [cytosol] (Canis familiaris)
Mad1 binds kinetochore (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
Mitotic checkpoint complex [cytosol] (Canis familiaris)
BUB1B [cytosol] (Canis familiaris)
Mad1:kinetochore complex [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
Mitotic checkpoint complex [cytosol] (Canis familiaris)
BUB1B [cytosol] (Canis familiaris)
Release of activated MAD2 from kinetochores (Canis familiaris)
Kinetochore:Mad1:MAD2 Complex [cytosol] (Canis familiaris)
Mad1:kinetochore complex [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
Mitotic checkpoint complex [cytosol] (Canis familiaris)
BUB1B [cytosol] (Canis familiaris)
Mad1:kinetochore complex [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
Mitotic checkpoint complex [cytosol] (Canis familiaris)
BUB1B [cytosol] (Canis familiaris)
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Canis familiaris)
Inactivation of APC/C via direct inhibition of the APC/C complex (Canis familiaris)
Binding of the MCC complex to the APC/C complex (Canis familiaris)
MCC:APC/C complex [cytosol] (Canis familiaris)
Mitotic checkpoint complex [cytosol] (Canis familiaris)
BUB1B [cytosol] (Canis familiaris)
Mitotic checkpoint complex [cytosol] (Canis familiaris)
BUB1B [cytosol] (Canis familiaris)
Formation of the MCC complex (Canis familiaris)
BUB1B [cytosol] (Canis familiaris)
Mitotic checkpoint complex [cytosol] (Canis familiaris)
BUB1B [cytosol] (Canis familiaris)
Cell Cycle, Mitotic (Canis familiaris)
M Phase (Canis familiaris)
Mitotic Metaphase and Anaphase (Canis familiaris)
Mitotic Anaphase (Canis familiaris)
Separation of Sister Chromatids (Canis familiaris)
ESPL1 (Separase) cleaves centromeric cohesin (Canis familiaris)
Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
Mitotic checkpoint complex [cytosol] (Canis familiaris)
BUB1B [cytosol] (Canis familiaris)
p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
Microtubule-bound kinetochore [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
Mitotic checkpoint complex [cytosol] (Canis familiaris)
BUB1B [cytosol] (Canis familiaris)
Separation of sister chromatids (Canis familiaris)
Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
Mitotic checkpoint complex [cytosol] (Canis familiaris)
BUB1B [cytosol] (Canis familiaris)
Sister Centromere:Kinetochore:Microtubules [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
Mitotic checkpoint complex [cytosol] (Canis familiaris)
BUB1B [cytosol] (Canis familiaris)
Mitotic Prometaphase (Canis familiaris)
EML4 and NUDC in mitotic spindle formation (Canis familiaris)
EML4 recruits NUDC to mitotic spindle (Canis familiaris)
Microtubule-bound kinetochore [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
Mitotic checkpoint complex [cytosol] (Canis familiaris)
BUB1B [cytosol] (Canis familiaris)
p-S274,S326-NUDC:EML4 homotrimer:Microtubule-bound kinetochore [spindle] (Canis familiaris)
Microtubule-bound kinetochore [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
Mitotic checkpoint complex [cytosol] (Canis familiaris)
BUB1B [cytosol] (Canis familiaris)
Resolution of Sister Chromatid Cohesion (Canis familiaris)
CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Canis familiaris)
Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
Ac-Cohesin:PDS5:WAPAL:Centromere:Kinetochore [chromosome, centromeric region] (Canis familiaris)
Sister Centromere:Kinetochore [chromosome, centromeric region] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
Mitotic checkpoint complex [cytosol] (Canis familiaris)
BUB1B [cytosol] (Canis familiaris)
Sister Centromere:Kinetochore [chromosome, centromeric region] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
Mitotic checkpoint complex [cytosol] (Canis familiaris)
BUB1B [cytosol] (Canis familiaris)
Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
Microtubule-bound kinetochore [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
Mitotic checkpoint complex [cytosol] (Canis familiaris)
BUB1B [cytosol] (Canis familiaris)
Kinetochore assembly (Canis familiaris)
Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
Ac-Cohesin:PDS5:WAPAL:Centromere:Kinetochore [chromosome, centromeric region] (Canis familiaris)
Sister Centromere:Kinetochore [chromosome, centromeric region] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
Mitotic checkpoint complex [cytosol] (Canis familiaris)
BUB1B [cytosol] (Canis familiaris)
Sister Centromere:Kinetochore [chromosome, centromeric region] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
Mitotic checkpoint complex [cytosol] (Canis familiaris)
BUB1B [cytosol] (Canis familiaris)
Microtubule-bound kinetochore [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
Mitotic checkpoint complex [cytosol] (Canis familiaris)
BUB1B [cytosol] (Canis familiaris)
PP2A-B56 dephosphorylates centromeric cohesin (Canis familiaris)
p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
Microtubule-bound kinetochore [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
Mitotic checkpoint complex [cytosol] (Canis familiaris)
BUB1B [cytosol] (Canis familiaris)
p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
Microtubule-bound kinetochore [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
Mitotic checkpoint complex [cytosol] (Canis familiaris)
BUB1B [cytosol] (Canis familiaris)
Phosphorylation of cohesin by PLK1 at centromeres (Canis familiaris)
Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
Microtubule-bound kinetochore [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
Mitotic checkpoint complex [cytosol] (Canis familiaris)
BUB1B [cytosol] (Canis familiaris)
p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Canis familiaris)
Microtubule-bound kinetochore [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
Mitotic checkpoint complex [cytosol] (Canis familiaris)
BUB1B [cytosol] (Canis familiaris)
Regulation of mitotic cell cycle (Canis familiaris)
APC/C-mediated degradation of cell cycle proteins (Canis familiaris)
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins (Canis familiaris)
APC/C:Cdc20 mediated degradation of mitotic proteins (Canis familiaris)
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint (Canis familiaris)
APC-Cdc20 mediated degradation of Nek2A (Canis familiaris)
Association of Nek2A with MCC:APC/C (Canis familiaris)
MCC:APC/C complex [cytosol] (Canis familiaris)
Mitotic checkpoint complex [cytosol] (Canis familiaris)
BUB1B [cytosol] (Canis familiaris)
Nek2A:MCC:APC/C complex [cytosol] (Canis familiaris)
MCC:APC/C complex [cytosol] (Canis familiaris)
Mitotic checkpoint complex [cytosol] (Canis familiaris)
BUB1B [cytosol] (Canis familiaris)
Degradation of multiubiquitinated Nek2A (Canis familiaris)
MCC:APC/C complex [cytosol] (Canis familiaris)
Mitotic checkpoint complex [cytosol] (Canis familiaris)
BUB1B [cytosol] (Canis familiaris)
Multiubiquitinated Nek2A [cytosol] (Canis familiaris)
Nek2A:MCC:APC/C complex [cytosol] (Canis familiaris)
MCC:APC/C complex [cytosol] (Canis familiaris)
Mitotic checkpoint complex [cytosol] (Canis familiaris)
BUB1B [cytosol] (Canis familiaris)
Multiubiquitination of Nek2A (Canis familiaris)
Multiubiquitinated Nek2A [cytosol] (Canis familiaris)
Nek2A:MCC:APC/C complex [cytosol] (Canis familiaris)
MCC:APC/C complex [cytosol] (Canis familiaris)
Mitotic checkpoint complex [cytosol] (Canis familiaris)
BUB1B [cytosol] (Canis familiaris)
Nek2A:MCC:APC/C complex [cytosol] (Canis familiaris)
MCC:APC/C complex [cytosol] (Canis familiaris)
Mitotic checkpoint complex [cytosol] (Canis familiaris)
BUB1B [cytosol] (Canis familiaris)
Cdc20:Phospho-APC/C mediated degradation of Cyclin A (Canis familiaris)
Association of Cyclin A with the APC/C (Canis familiaris)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Canis familiaris)
MCC:APC/C complex [cytosol] (Canis familiaris)
Mitotic checkpoint complex [cytosol] (Canis familiaris)
BUB1B [cytosol] (Canis familiaris)
MCC:APC/C complex [cytosol] (Canis familiaris)
Mitotic checkpoint complex [cytosol] (Canis familiaris)
BUB1B [cytosol] (Canis familiaris)
Degradation multiubiquitinated Cyclin A (Canis familiaris)
MCC:APC/C complex [cytosol] (Canis familiaris)
Mitotic checkpoint complex [cytosol] (Canis familiaris)
BUB1B [cytosol] (Canis familiaris)
multiubiquitinated Cyclin A associated with MCC:APC/C complex [cytosol] (Canis familiaris)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Canis familiaris)
MCC:APC/C complex [cytosol] (Canis familiaris)
Mitotic checkpoint complex [cytosol] (Canis familiaris)
BUB1B [cytosol] (Canis familiaris)
Ubiquitination of Cyclin A by APC/C:Cdc20 complex (Canis familiaris)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Canis familiaris)
MCC:APC/C complex [cytosol] (Canis familiaris)
Mitotic checkpoint complex [cytosol] (Canis familiaris)
BUB1B [cytosol] (Canis familiaris)
MCC:APC/C complex [cytosol] (Canis familiaris)
Mitotic checkpoint complex [cytosol] (Canis familiaris)
BUB1B [cytosol] (Canis familiaris)
multiubiquitinated Cyclin A associated with MCC:APC/C complex [cytosol] (Canis familiaris)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Canis familiaris)
MCC:APC/C complex [cytosol] (Canis familiaris)
Mitotic checkpoint complex [cytosol] (Canis familiaris)
BUB1B [cytosol] (Canis familiaris)
Activation of APC/C:Cdc20 by dissociation of Cdc20:phospho-APC/C from Cdc20:phospho-APC/C:Mad2:Bub3:BubR1 (Canis familiaris)
MCC:APC/C complex [cytosol] (Canis familiaris)
Mitotic checkpoint complex [cytosol] (Canis familiaris)
BUB1B [cytosol] (Canis familiaris)
hBUBR1:hBUB3:MAD2* complex [cytosol] (Canis familiaris)
BUB1B [cytosol] (Canis familiaris)
Regulation of APC/C activators between G1/S and early anaphase (Canis familiaris)
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Canis familiaris)
Inactivation of APC/C via direct inhibition of the APC/C complex (Canis familiaris)
Binding of the MCC complex to the APC/C complex (Canis familiaris)
MCC:APC/C complex [cytosol] (Canis familiaris)
Mitotic checkpoint complex [cytosol] (Canis familiaris)
BUB1B [cytosol] (Canis familiaris)
Mitotic checkpoint complex [cytosol] (Canis familiaris)
BUB1B [cytosol] (Canis familiaris)
Formation of the MCC complex (Canis familiaris)
BUB1B [cytosol] (Canis familiaris)
Mitotic checkpoint complex [cytosol] (Canis familiaris)
BUB1B [cytosol] (Canis familiaris)
Signal Transduction (Canis familiaris)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Canis familiaris)
Signaling by Rho GTPases (Canis familiaris)
RHO GTPase Effectors (Canis familiaris)
RHO GTPases Activate Formins (Canis familiaris)
AURKB phosphorylates DIAPH2-2 at kinetochores (Canis familiaris)
Kinetochore:CDC42:GTP:DIAPH2-2 [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
Mitotic checkpoint complex [cytosol] (Canis familiaris)
BUB1B [cytosol] (Canis familiaris)
Kinetochore:CDC42:GTP:p-S196-DIAPH2-2 [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
Mitotic checkpoint complex [cytosol] (Canis familiaris)
BUB1B [cytosol] (Canis familiaris)
CDC42:GTP recruits DIAPH2-2 to kinetochores (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
Mitotic checkpoint complex [cytosol] (Canis familiaris)
BUB1B [cytosol] (Canis familiaris)
Kinetochore:CDC42:GTP:DIAPH2-2 [cytosol] (Canis familiaris)
Kinetochore [cytosol] (Canis familiaris)
Mitotic checkpoint complex [cytosol] (Canis familiaris)
BUB1B [cytosol] (Canis familiaris)
External Reference Information
External Reference
UniProt:F1PLV9
Gene Names
BUB1B
Reference Genes
BioGPS Gene:608350 BUB1B
ENSEMBL:ENSCAFG00000008877
ENSEMBL_canis_lupus_familiaris_GENE:ENSCAFG00000008877 BUB1B
KEGG Gene (Canis lupus familiaris):608350 BUB1B
Monarch:608350 BUB1B
NCBI Gene:608350 BUB1B
Reference Transcript
RefSeq:XM_005638239.2 BUB1B
Other Identifiers
608350
CfaAffx.14101.1.S1_s_at
GO:0000003
GO:0000228
GO:0000278
GO:0000776
GO:0000777
GO:0000778
GO:0000940
GO:0003674
GO:0004672
GO:0005575
GO:0005622
GO:0005634
GO:0005694
GO:0005737
GO:0005819
GO:0005829
GO:0005856
GO:0006464
GO:0006468
GO:0007049
GO:0007059
GO:0007091
GO:0007094
GO:0008150
GO:0016301
GO:0032991
GO:0043226
GO:0048471
GO:0051276
GO:0051754
GO:0071459
GO:0140014
Participates
as a component of
hBUBR1:hBUB3:MAD2* complex [cytosol] (Canis familiaris)
Mitotic checkpoint complex [cytosol] (Canis familiaris)
as an input of
Formation of the MCC complex (Canis familiaris)
Inferred From
BUB1B [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_005638296.1
OpenTargets
ENSG00000156970
Ensembl
ENSCAFG00000008877
,
ENSCAFT00000014186
,
ENSCAFP00000013122
VGNC
38566
© 2022
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